... [39,40]. The E a values of BLXI inactivation were calculated for the apoenzyme in the presence and absence of metals(Table 3). The nature of the metal present clearly affected the E a of BLXI inactivation. ... relates to the enzyme’s functional temperature rangeand that BLXI thermostability is also directly related to the binding of specific metals as cofactors. At the same time, the simple relationship ... cytochrome c confer the stability of a thermophilic counterpart. J. Biol. Chem. 275, 37824 –37828.4. Numata, K., Hayashi-Iwasaki, Y. , Kawaguchi, J., Sakurai, M.,Moriyama, H., Tanaka, N. &...