Báo cáo y học: "Retinoid X receptor and peroxisome proliferator-activated receptor-gamma agonists cooperate to inhibit matrix metalloproteinase gene expression" potx

... article Retinoid X receptor and peroxisome proliferator-activated receptor- gamma agonists cooperate to inhibit matrix metalloproteinase gene expression Peter S Burrage 1 *, Adam C Schmucker 1 *, Yanqing ... retin- oic acid receptors, thyroid receptor, vitamin D receptor, PPARs, liver X receptors (LXRs), and farnesoid X receptor (FXR) [22], the ligand LG268...

Ngày tải lên: 09/08/2014, 13:22

... of allergic rhinitis, respiratory symptoms and asthma treatment by population group and sports category Variable N (%) General population Top athletes Endurance Motor Skills Team Sports Others N ... 291 German candidates for participation (65%) completed a questionnaire on respiratory and allergic symptoms. Results were compared to those of a general population study in Germany (n = 2...

Ngày tải lên: 08/08/2014, 21:20

... cross-linking additionally stimulates antigen-dependent cellular cytotoxicity by natural killer cells and macrophages. Conversely, FcγRIIb contains an inhibitory motif in the cytoplasmic tail that ... containing immune complexes/IgG autoantibodies, have been shown to play important roles in the initiation and regulation of many immunological and inflamma- tory processes and to amp...

Ngày tải lên: 09/08/2014, 08:22

... Research and Therapy by Hak and Choi’s study [1]. Menopause and hormone replacement therapies, possibly mediated by steroid hormones inducing a more efficient renal uric acid excretion, are thought to ... menopause, and aging has not been clearly defined by scientific evidence. In the present issue of Arthritis Research and Therapy, Hak and Choi present a cross- sectional analys...

Ngày tải lên: 09/08/2014, 13:22

... 2008, 14:818-829. 16. Yokoyama K, Kamata N, Fujimoto , Tsutsumi S, Tomonari M, Taki M, Hosokawa H, Nagayama M: Increased invasion and matrix metalloproteinase- 2 expression by Snail-induced mesenchymal transition ... different EMT regulators, Snail induces matrix * Correspondence: kjwu2@ym.edu.tw † Contributed equally 2 Institutes of Biochemistry and Molecular Biology, National Yang-...

Ngày tải lên: 10/08/2014, 05:21

... 1 and 3 days, and expression of GPVI at the surface detected by flow cytometry using convulxin (filled histogram). Back- ground fluorescence was obtained in the absence of convulxin (empty histograms). ... were fixed. GPVI–GFP was visualized by incubation with convulxin or an antibody to convulxin, and indirectly labelled with R-phycoerythin-conjugated anti-rabbit IgG. Fluorescent GFP is...

Ngày tải lên: 22/02/2014, 07:20

... MT-15624 to BHS; and National Institutes of Health grants EY06225, EY06226, and EY08571 to PAH and a departmental award from Research to Prevent Blindness. PAH is a recipient of a Senior Investigator ... R175Q was expressed from yeast cells and purified as previously described [12]. In both cases, the arrestin yielded a single band when analysed by SDS/ PAGE. Protein preparations...

Ngày tải lên: 22/02/2014, 07:20

... a-toxin II from the venom of the scorpion Androctonus australis hector; d-ACTX-Ar1, d-atraco- toxin-Ar1 ( formerly robustoxin) from Atrax robustus; d-ACTX-Hv1a, d-atracotoxin-Hv1a (formerly versutoxin) ... kinetics of toxin binding to receptor site-3 The binding properties o f the spider toxin, d-ACTX-Hv1a, to rat brain synaptosomes resemble those of scorpion a-toxins, thereby suggestin...

Ngày tải lên: 08/03/2014, 16:20

... NZB lymphocytes, NZW lymphocytes and (NZB × NZW)F 1 lymphocytes to P 2X 7 stimulation. NZB and NZW parental strains express the distinct P 2X 7 -L and P 2X 7 -P alleles of P2RX 7 , respectively, while lymphocytes ... the proinflammatory receptor P 2X 7 , and furthermore that NZW lymphocytes are markedly more responsive to P 2X 7 stimu- lation than those from NZB mice. Lym...

Ngày tải lên: 09/08/2014, 06:22

... Zhang Y, LaValley M, Chaisson CE, Aliabadi P, Felson DT: Symmetry and clustering of symptomatic hand osteoarthritis in elderly men and women: the Framingham Study. Rheuma- tology (Oxford) 2003, ... Occupational Health and Safety approved the study proposal. Hand radiography and image analysis Both hands of the participants were radiographed. Kodak X- ray films were exposed with Sie...

Ngày tải lên: 09/08/2014, 07:20