Báo cáo y học: "Therapeutic efficacy of intra-articular adrenomedullin injection in antigen-induced arthritis in rabbits" ppt

... the induction of arthritis in both knee joints by ovalbumin injection into the joint spaces of pre-immunized rabbits, increasing daily doses of adrenomedullin were injected into the knee joint ... concentrations of plasma adrenomedullin following intra-articular adrenomedullin injection in rabbits with antigen-induced arthritisSequential concentrations of plasma...

Ngày tải lên: 09/08/2014, 13:22

... we investigated the effects of leptin deficiency on zymosan-induced arthritis (ZIA), which is independent of adaptive immunity. Arthritis was induced by injection of zymosan into the knee joint. ... shown). Circulating levels of SAA increased in all animals during the first 3 days after intra-articular zymosan A injection (Table 1). Early after zymosan A injection the in...

Ngày tải lên: 09/08/2014, 01:23

... peptide ligand is its ability to alter the cytokine profile of responding T cells. We therefore determined the cytokine profile induced by analog peptides containing substitutions at residue ... individually by enzyme-linked immunosorbent assay to determine antibody levels against bovine CII. Results are means ± SD for each group of animals and are expressed in units of activity....

Ngày tải lên: 09/08/2014, 08:22

... Laboratories). Fluorescent staining of lymphoid cells in spleens and kidneys Frozen sections were used for examination of lymphoid cell subsets in spleen and cell infiltration in kidneys. For determina- tion of CD3 + ... Yang MS: Involvement of NF-kappaB and c-myc signaling pathways in the apoptosis of HL-60 cells induced by alkaloids of Tripterygium hypoglaucum (levl.) H...

Ngày tải lên: 09/08/2014, 07:20

... also pathologically crucial in the early effector phase in arthritis. Role of various inflammatory cytokines in GPI-induced arthritis To determine the effects of inflammatory cytokines during the effector ... production during this phase of GPI-induced arthritis. Figure 4 Concentration of inflammatory cytokines in serum of mice with GPI-induced arthritisConcentration...

Ngày tải lên: 09/08/2014, 10:23

... (Figure 2b). In contrast, STA-5326-treated mice exhibited some inflammatory cell infiltration into the vitreous cavity, but only a few infiltrating cells in the retina with retinal layers remaining intact ... likely that STA-5326 blocks c-Rel translocation in ocular tissues and infiltrating inflamma- tory cells, including ocular antigen presenting cells, resulting in inhibition of g...

Ngày tải lên: 09/08/2014, 13:22

... immunoglobulin chains were also found to be significantly increased in aged thymocytes. Understanding the changes in gene expression in thymocytes with age may hold the key in determining thymocyte ... thymus, involution, aging, microarray, AGEMAP, thymocytes, caloric restriction Introduction The aging immune system is often characterized by a general decline in the ability to...

Ngày tải lên: 03/11/2012, 11:35

... recombinant protein containing the C-myc epitope followed by six histidines at the C-terminus. A plasmid containing the wild type version of CCR5 was constructed by introducing the coding sequence ... the C-terminus of CCR5 would interfere with the protein’s ability to function as a chemokine receptor or HIV coreceptor, we first determined the binding of MIP-1a to the CCR5-myc-his expres...

Ngày tải lên: 08/03/2014, 09:20

... access [14]. In contrast to all Fe-hydrogenases including HydA of S. obliquus,the enzyme of C. reinhardtii has an interesting additional protein domain. A small insertion of 45 amino acids between ... synthesis of s ome enzymes involved in glycolysis or sugar-phosphate metabolism [54]. HydA belongs to a new class of Fe-hydrogenases HydA of C. reinhardtii, the first isolated gen...

Ngày tải lên: 08/03/2014, 22:20

... expression of a variety of single mitochondrial-type AACs in E. coli. After IPTG-induction we were able to obtain functional integration of the various mitochondrial-type AACs into the cytoplasmic ... trans- ferredtonewreactionvesselsandheatedto95°Cfor 10 min to prevent any further reaction. An aliquot of the exported radioactive solution was used for separation by thin-layer chroma...

Ngày tải lên: 18/03/2014, 01:20