... implicated in synaptic plasticity, and play a role in repair of the nervous system following injury [30-32]. Cancer Eph receptor and ephrin ligand signaling is known to play a role in many types of ... preaxial polydactyly was still present. Despite evidence for the involvement of the sonic hedgehog pathway in polydactyly, no evidence was found for a role for this pathway in the p...
Ngày tải lên: 08/08/2014, 17:20
... FRCPath, and Solomon O. Odemuyiwa, DVM, PhD A recent review in Allergy, Asthma, and Clinical Immunology suggested that eosinophils play a minor role, if any, in the inflammatory spectrum of asthma and ... understanding the potential func- tions of various cells and molecules but may not necessarily generate the best therapeutic options in a disease character- ized by complex cellular...
Ngày tải lên: 08/08/2014, 21:20
Báo cáo y học: "Differential Constitutive and Cytokine-Modulated Expression of Human Toll-like Receptors in Primary Neutrophils, Monocytes, and Macrophages" docx
... Constitutive and Cytokine-Modulated Expression of Human Toll-like Receptors in Primary Neutrophils, Monocytes, and Macrophages D. Shane O’Mahony 1 , Uyenvy Pham 1 , Ramesh Iyer 1 , Thomas ... TLR2 and TLR4 in neutrophils and monocytes. GM-CSF up-regulated expression of TLR2 and TLR4 in neutrophils and TLR2 in monocytes. TLR5 was down-regulated by inflammatory cytokines in...
Ngày tải lên: 08/08/2014, 16:23
Báo cáo y học: "The relationship between inflammation and new bone formation in patients with ankylosing spondylitis" docx
... Similarly, for assessment and quantification of inflamma- tory spinal changes, the AS-spinal-MRI scoring system [13] has shown good discriminatory capacity, validity, and sensitiv- ity to change ... inhibited by TNF blockers. Figure 1 Formation of new syndesmophytes in the upper and lower edges of L1/L2 and L2/L3Formation of new syndesmophytes in the upper and lower edges of L1/L2...
Ngày tải lên: 09/08/2014, 13:21
Báo cáo y học: " mGluR5 positive modulators both potentiate activation and restore inhibition in NMDA receptors by PKC dependent pathway" docx
... mGluR5 agonist (RS)-2-chloro-5-hydroxyphenylglycine (CHPG), as well as the positive allosteric modulators 3-cya no- N-(1,3-diphenyl-1H-pyrazol-5-yl) benzamide (CDPPB) and 3,3’- difluorobenzaldazine ... (GPCR) and influence a variety of intracellular second messenger systems that modulate neuronal excitability, synaptic p lasticity, and neurodegeneration. mGluRs are involved in physiolog...
Ngày tải lên: 10/08/2014, 05:21
Báo cáo y học: "Granulocyte-CSF induced inflammation-associated cardiac thrombosis in iron loading mouse heart and can be attenuated by statin therapy" pptx
... PE-conjugated rat anti-mouse CD11b antibody and FITC-conjugated Ly-6G monoclonal antibody separately, then flow cytommetry was performed on a BD FACScan flow cytometry system. Experiments were performed ... I+G+St mice (Table 2). Flow cytometry analysis of CD11b and Ly6G proteins (myeloid cells surface markers expressed mainly on the monocytes, macrophages and granulocytes) showed incre...
Ngày tải lên: 10/08/2014, 05:21
Báo cáo y học: "Teaching child and adolescent psychiatry to undergraduate medical students - A survey in German-speaking countries"
... medical students - A survey in German- speaking countries. Child and Adolescent Psychiatry and Mental Health 2010 4:21. Frank and Frank Child and Adolescent Psychiatry and Mental Health 2010, 4:21 http://www.capmh.com/content/4/1/21 Page ... schools and building networks among the different departments of child and adult psychiatry nationally and also internation- ally will co...
Ngày tải lên: 25/10/2012, 10:06
Báo cáo y học: "Translational Medicine and Reliability of Single-Nucleotide Polymorphism Studies: Can We Believe in SNP Reports or Not"
... [3,5] and may be cited more often than negative studies [6,7]; 3) null papers are typically given low publication priority scores and may not be accepted for publication [2], we hypothesized ... and lung malig- nancy) SNPs for GST polymorphisms were used as a substrate for analyses. Materials and Methods Search strategy and eligibility criteria We electronically searched the...
Ngày tải lên: 25/10/2012, 10:51
Báo cáo y học: "Ozone Therapy and Hyperbaric Oxygen Treatment in Lung Injury in Septic Rats"
... initially, and sepsis leads to severe injury in lung tissue [5]. It has been shown that pericytes in lung tissue produce proinflammatory cytokines in response to lipopolysaccharide (LPS) [6]. Hyperbaric ... comprising ozone and oxygen to body fluids and cavities. The ozone/oxygen mixture was reported to exhibit various effects on the immune system, such as the modulation of phago...
Ngày tải lên: 25/10/2012, 11:18