Weekly intra-articular injections of bone morphogenetic protein-7 inhibits osteoarthritis progression pot

... http://arthritis-research.com/content/10/5/R118 Page 1 of 9 (page number not for citation purposes) Vol 10 No 5 Research article Weekly intra-articular injections of bone morphogenetic protein-7 inhibits osteoarthritis progression Masaya ... forma- Figure 1 Evaluation of dose effect of BMP-7 for prevention of osteoarthritis progression in rabbit ACLTEvaluation...

Ngày tải lên: 09/08/2014, 13:22

... time of 8 h at 37 °C. For glycosylation trimming, a mixture of 1 mU of PNGase F3 and 1 mU of PNGase H was used per microgram of hBMP-6, with a reaction time of 24 h at 37 °C. The completeness of ... important role in type I receptor specificity of BMP-6. Abbreviations ActR, activin receptor; ALP, alkaline phosphatase; BMP, bone morphogenetic protein; BMPR, bone morphogen...

Ngày tải lên: 23/03/2014, 07:20

... most studied member of the family and has been used in many studies for augmentation of bone and bone- ten- don junction regeneration [3,4]. Because of the role of BMP-2 in bone formation, it is ... citation purposes) Journal of Orthopaedic Surgery and Research Open Access Research article Expression of Bone Morphogenetic Protein-2 in the Chondrogenic and Ossifying Site...

Ngày tải lên: 20/06/2014, 04:20

... pro- tein-1 (bone morphogenetic protein-7) in the treatment of tib- ial nonunions. J Bone Joint Surg Am 2001, 83-A(Suppl 1):S151-S158. 8. Lories RJ, Derese I, Luyten FP: Modulation of bone morphoge- netic ... TG, Mackillop N, Dougados M: Synovitis: a potential predictive factor of structural progres- sion of medial tibiofemoral knee osteoarthritis – results of a 1 year lon...

Ngày tải lên: 09/08/2014, 07:20

... the problem of inadequate bone healing. In addition, high concentrations - at high cost - of single growth factors with a range of questionable carriers is the current paradigm for bone induction ... osteo- genic differentiation of MSCs, but their effects are markedly different. The suppression of chordin led to increased availability of BMP-2 and subsequently differentiation...

Ngày tải lên: 09/08/2014, 10:23

... g) and 25 μm (b, d, f, h). Figure 5 Presence of bone morphogenetic protein-7 (BMP7) during collagen-induced arthritisPresence of bone morphogenetic protein-7 (BMP7) during collagen- induced arthritis. ... effect of blocking TNFα on expression of BMPs in synovium and carti- Figure 1 Activation of bone morphogenetic protein signaling in the mouse knee during collagen-i...

Ngày tải lên: 09/08/2014, 13:22

... T-score of 2.3 and a body mass index of 28 kg/m 2 , which was revised to a THA at two months post-operatively; the other case was in a female patient with a T-score of -2.1 and body mass index of ... divided into the two groups of Osteoarthritis and Not Osteoarthritis; femoral implant fixation type was included as a categorical variable and divided into the groups of Cemente...

Ngày tải lên: 20/06/2014, 07:20

... 2963 MINIREVIEW Bone morphogenetic proteins in the early development of zebrafish Mariko Kondo* Department of Biological Sciences, The University of Tokyo, Japan Introduction Bone morphogenetic ... only one report of a mutant strain of the BMP receptor. The dorsalized mutant lost-a-fin (laf) (C2 phenotype) is a mutant of the alk8, the gene cod- ing a member of the ALK1 sub...

Ngày tải lên: 19/02/2014, 00:20

... portion (Figure 4). Expression of mRNA for bone morphogenetic protein, matrix proteins, and cytokines Figures 5 and 6 show the results of expression profiles obtained from areas of the bursa that are ... 1 of 9 (page number not for citation purposes) Vol 8 No 4 Research article Expression of bioactive bone morphogenetic proteins in the subacromial bursa of patients with...

Ngày tải lên: 09/08/2014, 08:22

... calcifying zone of cartilage could be clearly separated by the proximity of the cells to the joint space and the bone respectively, alignment of the chondrocytes along the arcades of Benninghoff [29] ... cartilage, and CS4, one of the monomers of the polysaccharide portion of proteoglycan, showed significantly enhanced production of these cartilage matrix proteins at days 10...

Ngày tải lên: 09/08/2014, 14:22