Báo cáo y học: "Role of STAT4 polymorphisms in systemic lupus erythematosus in a Japanese population: a case-control association study of the STAT1-STAT4 region" pot

... transplant-related mortality. Autoimmune Disease and Lymphoma Working Parties of the European Group for Blood and Marrow Trans- plantation, the European League Against Rheumatism and the International Stem ... support. Competing interests None declared. References 1. Marmont AM, van Lint MT, Gualandi F, Bacigalupo A: Autologous marrow stem cell transplantation for severe systemic...

Ngày tải lên: 09/08/2014, 01:23

... systemic lupus erythematosus in a Japanese population: a case-control association study of the STAT1 -STAT4 region Aya Kawasaki 1 , Ikue Ito 1 , Koki Hikami 1 , Jun Ohashi 1 , Taichi Hayashi 2 , Daisuke ... Tsukahara S, Kawaguchi Y, Terai C, Hara M, Tomatsu T, Yamanaka H, Horiuchi T, Tao K, Yas- utomo K, Hamada D, Yasui N, Inoue H, Itakura M, Okamoto H, Kamatani...

Ngày tải lên: 09/08/2014, 13:22

... significant potential clinical consequences. In a study by Martinez and colleagues, 269 children who were b2 naive, participating in a longitudinal asthma study, had their bronchodilator response measured ... response. Tantisira and colleagues investigated the genetic contribution to the variation in response to ICS therapy in asthma by assessing the association of ch...

Ngày tải lên: 08/08/2014, 21:20

... fatty acid synthesis in the liver. ACC, the rate-limiting en- zyme that catalyzes the carboxylation of acetyl-Co A to form malonyl-CoA, is the pivotal enzyme in the biosynthesis of long-chain ... manipulation of the amount and nature dietary energy and fat intakes. In recent years, increased at- tention has shifted toward the role of dietary protein intake...

Ngày tải lên: 31/10/2012, 14:59

... among plants and cyanobacteria, the surface charge pattern varies greatly [1]. Comparing cyanobacterial data with the wealth of information available for the higher plant reaction [2–5] reveals ... previously [1] that in vitro the plant and cyanobacterial systems reach similar rates in different ways: the plant system uses mainly electrostatic interactions, as indicated by th...

Ngày tải lên: 21/02/2014, 01:21

... 2355 Role of sulfoquinovosyl diacylglycerol for the maintenance of photosystem II in Chlamydomonas reinhardtii Ayumi Minoda 1 , Norihiro Sato 1 , Hisayoshi Nozaki 2 , Katsuhiko Okada 1 , Haruko Takahashi 1 , Kintake ... that SQDG participate in PSII activity in C. reinhardtii. MATERIALS AND METHODS Algal culture SQDG-deficient mutant of C. reinhardtii,whichwasdesig- nated as hf-2...

Ngày tải lên: 22/02/2014, 04:20

... shown). AA interacts extracellularly In order to assess whether AA acts extracellularly during Ca 2+ in ux, we used the fatty acid free BSA at a final concentration of 0.2% (w/v) as this concentration ... report in which docosahexaenoic acid, a polyunsaturated fatty acid, affects the calcium channels in an albumin reversible manner [42]. The present study demonstrates that...

Ngày tải lên: 08/03/2014, 09:20

... not involved in any intraprotein interaction, but is situated at the entrance of a water cavity, at the bottom of which are the pyrophosphate and the ribose from the FAD. Therefore, K75 cannot ... experimentally either the K d or the binding energies for the apoFNR:FAD complexes in any redox state. However, as the reduction potentials of free and bound FAD are li...

Ngày tải lên: 08/03/2014, 23:20

... between a serine hydroxyl and an aspartic acid, these experiments argue strongly against an acidic function of the serine hydroxyl; (d) upon replacing serine by alanine the enzyme remains reasonably ... member of the sodium ion transport decarboxylase family of enzymes, which also includes methylmalonyl-CoA decarboxylase, malonate decarboxylase and glutaconyl-CoA decarboxylase f...

Ngày tải lên: 08/03/2014, 23:20

... residue interacting with the a- amino group of the substrate and with a buried water molecule). Y2 24 in pkDAAO and Y2 38 in RgDAAO share the characteristics of being flexible and adapting their conformation ... to the N(5) flavin position is also marginally altered by the substitution of Y2 38 (Table 2). Steady-state and rapid reaction kinetics with D -alanine The a...

Ngày tải lên: 17/03/2014, 17:20