... measure significant rates of amylose synthesis and we can only state that the latter certainly does not exceed the rate of amylopectin synthesis. The increase in crystallinity wit- nessed during these first 12 ... displays the length and position of the six introns within the GBSSI sequence compared with those of rice and potato. The number and position of t...
Ngày tải lên: 22/02/2014, 07:20
Báo cáo y học: "Reduced proportions of natural killer T cells are present in the relatives of lupus patients and are associated with autoimmunity" ppt
... correlation between the proportion of total NKT cells and disease activity or drug therapy in our lupus patients, which suggests that the reduction in NKT cells in these patients does not arise ... cytokines that are secreted by the NKT cells in the different lupus mouse models, with interleukin-4-secreting NKT cells inhibiting lupus and interferon-γ...
Ngày tải lên: 09/08/2014, 13:21
... respectively) to the proteins enco- ded by ORFs in the clusters responsible for synthesizing the SPAs in other serotypes of A. actinomycetemcomitans. The biosynthetic pathway for GDP-6-deoxy- D -talose, Fig. ... regardless of the addition of the proteins. The peak that appeared at 24.0 min was in agreement with that of authentic NADP + . The reason why the NA...
Ngày tải lên: 17/03/2014, 10:20
Báo cáo Y học: Cytochrome c from a thermophilic bacterium has provided insights into the mechanisms of protein maturation, folding, and stability potx
... isolated from thermophilic bacteria are usually stable to heat and chemical denaturants, indicating that they must have most of the determinants of protein stability. Initial clues to the relationship ... character of HT c-552 may depend on a few strong noncovalent interactions. We further found that the increase in the stability of the quintuple mutant is almost the...
Ngày tải lên: 24/03/2014, 03:21
Báo cáo Y học: Mistletoe viscotoxins increase natural killer cell-mediated cytotoxicity pptx
... cytolytic activity against the activating target, nor does it weaken the latter in such a way as to increase their lysis in the assay. Besides the lack of viscotoxin toxicity for the various targets cells ... bioactive in NK lysis are VTA1-3 On the one hand, proteins were unexpected for the unusual thermostability and protease-insensitivity of the bioactive ext...
Ngày tải lên: 31/03/2014, 15:20
Báo cáo y học: "THR0921, a novel peroxisome proliferator-activated receptor gamma agonist, reduces the severity of collagen-induced arthritis" pps
... As the involvement of each of these cytokines in the pathogenesis of arthritis is well Figure 5 Steady state mRNA levels of the inflammatory cytokines IL-1β, mono-cyte chemotactic protein (MCP)-1, ... this may be a primary mechanism by which THR0921 provides clinical benefit. The effect of THR0921 and other PPARγ ligands may be due to their ability to inhibit the activ...
Ngày tải lên: 09/08/2014, 07:20
Báo cáo y học: " High-mobility group box protein 1 (HMGB1): an alarmin mediating the pathogenesis of rheumatic disease." docx
... construct on the function of HMGB1, the important issue is not the contribution of any possible ‘contamination’ of purified HMGB1 in in vitro experiments but rather the actual function of the ... Down-regulation of the aberrant expression of the inflammation mediator high mobility group box chromosomal protein 1 in muscle tissue of patients with polymyositi...
Ngày tải lên: 09/08/2014, 10:23
Báo cáo y học: "Genomic transcriptional profiling identifies a candidate blood biomarker signature for the diagnosis of septicemic melioidosis" ppsx
... collected from patients with septicemic melio- idosis and patients with sepsis and isolation of other organ- isms in the training and the two test sets concerning the total leukocyte, platelet, ... constituting an excellent tool in the dis- covery phase, are currently inadequate for routine testing. Indeed, the data that are generated are not quantitative...
Ngày tải lên: 09/08/2014, 20:20
Báo cáo y học: " Protein kinase A-dependent Neuronal Nitric Oxide Synthase Activation Mediates the Enhancement of Baroreflex Response by Adrenomedullin in the Nucleus Tractus Solitarii of Rats" pps
... conceived of the study, designed and coordinated the experiments, and drafted the manuscript. All authors read and approved the final manuscript. Competing interests The authors declare that they have ... neuron. The enzyme activity of nNOS has been demonstrated to be intimately associated with the state of phosphorylation at the amino acid residues Ser847 and...
Ngày tải lên: 10/08/2014, 05:21
Báo cáo y học: " Non infective severe aortic paravalvular leakage 7 years after surgery: the role of suture technique" pot
... a partial prosthesis detachment at the level of the non coronary aortic sinus, due to the semicontinuous suture breaking (Figure 2). The other two sutures of the left and right coronary sinuses ... the aortic annulus and sew- ing ring of the artificial valve prior to lower the prosthe- sis. Then a gentle alternate traction on the three semicontinuous sutures, usual...
Ngày tải lên: 10/08/2014, 09:21