Báo cáo y học: "Upregulated miR-146a expression in peripheral blood mononuclear cells from rheumatoid arthritis patients" doc

... 2.6-fold increase in miR-146a expression and a 1.8-fold increase in miR-155 expression. Because of the invasiveness involved in collecting samples, monitoring miRNA expression in RA synovial tissue ... prednisone, mycophenolate mofetil SjS1 Female 30 Hydroxychloroquine, mycophenolate mofetil SjS2 Male 21 Hydroxychloroquine SSc1 Female 57 Cyclosporine, hydroxychloroquine, predni...

Ngày tải lên: 09/08/2014, 13:21

... of reaching the immune system and peripheral blood stream. Therefore, we hypothesized that the percent of peripheral blood mononuclear cells (PBMCs) displaying p-STAT-3 may be increased in malignant ... necrosis factor alpha, and interleukin-6 in activated peripheral blood lymphocytes from glioma patients. J Interferon Cytokine Res 1995, 15:421-429. 25. Hussain SF, Kong...

Ngày tải lên: 18/06/2014, 15:20

... Rodan GA, Rosenblatt M: Inhibition of osteoclastic bone resorption in vivo by echistatin, an "arginyl-glycyl-aspartyl" (RGD)-containing protein. Endocrinology 1993, 132:1411-1413. 34. ... monocytes may be an important source of inflammatory cytokines. In mice, peripheral blood Ly-6C high monocytes, which are thought to correspond to human CD16 - monocytes, increase in i...

Ngày tải lên: 09/08/2014, 08:22

... subtypes including one characterized by host inflammatory response. Blood 2005; 105:1851- 1861. 23. Heckman CA, Mehew JW, Ying GG, et al. A-Myb up-regulates Bcl-2 through a Cdx binding site in ... monkey lymphomas and monkey B-lymphocytes. Those cDNAs whose hybridization signals were markedly stronger with lymphoma cDNA than with cDNA of B- lymphocytes were further analyzed by North...

Ngày tải lên: 02/11/2012, 11:08

... and CXC chemokines, with a single amino acid separating the first two cysteines. Cys–X–Cys ligand (CXCL)9 and CXCL10 are members of the small cytokine (intercrine/chemokine) CXC subfamily and represent ... CXCR3 expression was originally shown to be restricted to activated T lympho- cytes [5,22,23] and could be observed in resting T lym- phocytes, B lymphocytes, monocytes or granulocytes...

Ngày tải lên: 09/08/2014, 01:23

... analyzed individually. Flow cytometry analysis The cell type composition and level of protein expression for some genes in the inguinal lymph nodes were analyzed by flow cytometry. Single cell ... respectively). Discussion By using microarray and real-time PCR, we investigated differential gene expression in the draining inguinal lymph nodes between the arthritis- susceptible DA and...

Ngày tải lên: 09/08/2014, 01:23

... incu- bated with Tris-buffered saline containing isotype-matched antibodies instead of the primary antibody; they were invar- iably negative (data not shown). The intensity of antibody staining ... these molecules in synovial inflammatory responses, offering new insights into elements controlling the immune response within joints. Competing interests The author(s) declare that they have no...

Ngày tải lên: 09/08/2014, 06:22

... of rheumatoid arthritis. Int J Clin Pract 2003, 57:231-234. 33. Le Maitre CL, Freemont AJ, Hoyland JA: A preliminary in vitro study into the use of IL-1Ra gene therapy for the inhibition of intervertebral ... Cho YW, Ahn MW, Jang SH, Sohn YK, Kim HS: mRNAexpression of cytokines and chemokines in herniated lumbar intervertebral discs. Spine 2002, 27:911-917. 9. Kang JD, Georgescu HI, Mc...

Ngày tải lên: 09/08/2014, 10:20

... protein expression in PBMCs from patients with BD. (a) Effect of lipopolysaccharide (LPS) stimulation on heme oxygenase (HO)-1 and actin protein expression in peripheral blood mononuclear cells ... elevated soluble CD14 in plasma of BD patients may further facilitate LPS binding to TLR4 [36]. Inter- estingly, LPS-induced lung injury in a mouse model was res- cued by adm...

Ngày tải lên: 09/08/2014, 10:22

... For instance, a patient giving into this dependence shouldn't discontinue their medication, possibly developing symptom clusters inducing polypharmacy [18]. Alternatively, a patient having ... the experienced pain. Again, looking back to Ancient Greek mythology, it is easy to find many explanations for this kind of mentality, prej- udice and concern against the 'doctor and his drugs...

Ngày tải lên: 08/08/2014, 23:21