Báo cáo y học: "Lipooxygenase inhibition in osteoarthritis: a potential symptomatic and disease modifying effect" ppsx

... levels. Editorial Lipooxygenase inhibition in osteoarthritis: a potential symptomatic and disease modifying effect? Maxime Dougados Paris-Descartes University, Medicine Faculty; UPRES-EA 4058; AP-HP, Cochin Hospital, ... considered as a potent lipooxygenase inhibitor. The results observed in a preliminary trial suggest a highly intriguing clinically relevant symptom...

Ngày tải lên: 09/08/2014, 11:20

... respectively; inter- and intraassay coefficient of variation for all assays: <10%. Presentation of data and statistical analysis Data in the table are given as means ± SEM and data in figures are ... for histology: samples intended for hematoxylin-eosin (HE) staining and alkaline phosphatase-anti-alkaline phosphatase (APAAP) staining were immediately placed in protective free...

Ngày tải lên: 09/08/2014, 06:23

... observed at increased rate in RA. Very few studies have addressed the role of MMP2 in RA. It has been assumed that MMP2 promotes RA by participating in cartilage degradation and by activating pro-inflammatory mediators ... Konttinen YT, Ainola M, Valleala H, Ma J, Ida H, Mandelin J, Kinne RW, Santavirta S, Sorsa T, Lopez-Otin C, Takagi M: Analysis of 16 different matrix metalloprotein...

Ngày tải lên: 09/08/2014, 07:20

... T2DM, hypertension, and coronary artery disease. In the ensuing years, the concept of insulin resistance and associated metabolic abnormalities leading to increased risk of CVD became known as insulin ... impaired glucose tolerance, and impaired fasting glycemia), and hypertension [3]. Features like a systemic pro-inflammatory state, accelerated hemostasis, and impaired fibrino...

Ngày tải lên: 09/08/2014, 10:23

... Presence of anti-kinectin and anti-PMS1 antibodies in Japanese aplastic anaemia patients. Br J Haematol 2005, 128:221-223. 39. Imai H, Nakano Y, Kiyosawa K, Tan EM: Increasing titers and changing specificities ... vasculitic disease involv- ing pathophysiology of endothelial cells, and antibody to endothelial cell antigen (AECA) has been reported. Reports on the prevalence of AECA...

Ngày tải lên: 09/08/2014, 07:20

... combat HIV infection and disease. TPCK (N -a- p-tosyl-L- phenylalanine chloromethyl ketone) and TLCK (N -a- p-tosyl-L-lysine chloromethyl ketone) are alkylation reagents that chemically modify the ... this article as: Jin et al.: Alkylating HIV-1 Nef - a potential way of HIV intervention. AIDS Research and Therapy 2010 7:26. Submit your next manuscript to BioMed Central and take...

Ngày tải lên: 10/08/2014, 05:21

... Carney RM, Kenneth KE, Stein PK, Skala JA, Hoffman P, Jaffe AS: Change in heart rate and heart rate variability during treatment for depression in patients with coronary artery disease. Psychosom ... PM, Vaschillo E, Vaschillo B: Resonant frequency biofeedback training to increase cardiac variability: rational and manual training. Appl Psychophys Biof 2000, 25:177-191. 32. Nahsho...

Ngày tải lên: 10/08/2014, 09:22

... & lower lobectomy 5 years ago. CP: carinal plasty with reinplantation of the right main bronchus to the trachea for Tracheal Sarcoma (TS) or carcinoid tumor A: Alive D:Dead Parissis and Young ... 121:465-71. 9. Macchiarini P, Altmayer M, Go T, Walles T, Schulze K, Wildfang I, Haverich A, Hardin M: Hannover Interdisciplinary Intrathoracic Tumor Task Force Group. Technical innovations...

Ngày tải lên: 10/08/2014, 09:22

... tenocytes. 23. Wakisaka S, Suzuki N, Takeba Y, Shimoyama Y, Nagafuchi H, Takeno M, Saito N, Yokoe T, Kaneko A, Asai T, Sakane T: Modu- lation by proinflammatory cytokines of Fas/Fas ligand-medi- ated ... TNF-α in triggering and modu- lating apoptosis is less clearly defined. This is because, in addition to signalling through the death domain of TNFRI, TNF-α activates mainly signallin...

Ngày tải lên: 09/08/2014, 01:23

... Tsuruha J, Masuko-Hongo K, Kato T, Sakata M, Nakamura H, Nishioka K: Implication of cartilage intermediate layer protein in cartilage destruction in subsets of patients with osteoarthritis and ... immunomodulative agent. Competing interests None declared. References 1. Nakamura H, Yoshino S, Kato T, Tsuruha J, Nishioka K: T-cell mediated inflammatory pathway in osteoarthritis. Osteoar...

Ngày tải lên: 09/08/2014, 01:23