Báo cáo y học: "Identification of intra-group, inter-individual, and gene-specific variances in mRNA expression profiles in the rheumatoid arthritis synovial membrane" pot

... liverF X X X X X X X X X XXX X XX X X X X X X X X X X XXX X X X X X X X X XXXX X X X X X X X X XX X X XX X X X X X X X X X X X X XXX X XXX X X XX X X X XXXX X X X X X X X X X X X X X X X X X X X X X X X X XX X X XX X XXX X X X X X X X X X X X X X X X X X X XX X X X X X X XXXX X X X X X X X X XX X X X XX X X X X X X X X X X X X X X X X X X X X XXX X X X X X X XX X X X XXX X X X X X X XXXX X XX...

Ngày tải lên: 09/08/2014, 20:22

... suppression of MM12.10 labeling after UIC2 binding) may be intrinsic to the normal catalytic cycle, or, alternatively, the CsA-type drugs may induce a special conformation adopted by Pgp only in the ... These findings may be interpreted suggesting that changes in the UIC2 reactivity of Pgp are brought about by nucleotide binding and release [18,30], or assuming that the hyd...

Ngày tải lên: 08/03/2014, 23:20

... none of them could name it. Interestingly, while the interviewees could not name the disease that was infecting the crabs in the region, all of them could identify the major clinical symptoms of ... the period just prior to the arrival of the disease. Interestingly, none of the crab harvesters knew the official name of this disease. According to most of...

Ngày tải lên: 10/08/2014, 09:22

... this study. The presence of dyspeptic com- plaint and its severity calculated by presence of ab - dominal pain, abdominal pain with hungry and an - xiety, abdominal distension, nausea, vomiting, ... history, and certain laboratory data may guide the choice of which endoscopic in - vestigation to perform first in patients with IDA, the- reby, potentially reducing the f...

Ngày tải lên: 25/10/2012, 11:18

... determine the identity of the interacting proteins. 3. Results and Discussion 3.1 Principle of Split-Ubiquitin Screening System Studies have shown that the use of yeast two hybrid system, which is ... Construction of cDNA Library in S. cerevisiae DSY-2 Strain The cDNA library was prepared by transforming the yeast S. cerevisiae DSY-2 strain, in which the cDNA m...

Ngày tải lên: 02/11/2012, 11:08

... isobutyl-methylxanthine and indomethacin. About 10–30% of the OC cells were reproducibly induced toward the adipogenic lineage as early as 2 weeks after induction (Fig. 5g,5h). Using PCR, the expression of peroxisome ... and analyzed the kinet- ics of cultivation and the potential for differentiation. The data analysis after sorting is exemplarily shown for one patie...

Ngày tải lên: 09/08/2014, 01:23

... summa- rized in Fig. 2, including intra-assay and interassay variability (Fig. 2a), linearity (Fig. 2b), and ROC analysis, PPV, NPV and efficiency (Fig. 2c). To determine the cutoff, the focus was ... shown). The absence of inhibition can be explained by the variety of different anti-Sm antibody sub- populations and by the variety of corresponding epitopes. Recently,...

Ngày tải lên: 09/08/2014, 06:22

... integrins to the cytoskeleton and recruit sig- naling molecules [33]. A new study reported that a kinectin isoform lacking a major portion of the kinesin-binding domain is very probably the most ... throughout the study. SLC and EMT con- ceived the study, participated in the design and helped in the analysis of the data. EKLC participated in the design of...

Ngày tải lên: 09/08/2014, 07:20

... 6 Localisation of citrullinated proteins in synovial membranesLocalisation of citrullinated proteins in synovial membranes. (a) Immunostaining of citrullinated proteins by the anti-modified citrulline kit ... confirming the identity of the autoantigen. Conversion of arginine to citrulline results in a mass increase of 0.984 Da and a loss of the positive charg...

Ngày tải lên: 09/08/2014, 07:20

... RNA and poly (A) + RNA from joints After removal of the skin and muscle, portions of the leg con- taining the knee, ankle, and finger joints were rapidly frozen in liquid nitrogen. Frozen joints ... synovial lining and fluid of the periarticular spaces [2]. The infiltrating cells express adhesion molecules and produce a variety of inflammatory cytokines and...

Ngày tải lên: 09/08/2014, 08:22