Báo cáo y học: "Circulating immune complexes contain citrullinated fibrinogen in rheumatoid arthritis" ppt

... purposes) Figure 1 Fibrinogen- containing circulating immune complexes (ICs) in rheumatoid arthritis (RA )Fibrinogen- containing circulating immune complexes (ICs) in rheumatoid arthritis (RA). Circulating (a) ... 2 Citrullinated fibrinogen- containing immune complexes (ICs) are separated from rheumatoid arthritis (RA) plasmaCitrullinated fibrinogen- containing imm...

Ngày tải lên: 09/08/2014, 10:23

... strategy for RA, involving early Commentary The value of sensitive imaging modalities in rheumatoid arthritis Peter C Taylor The Kennedy Institute of Rheumatology Division, Faculty of Medicine, ... ultrasonography. Arthritis Research & Therapy Vol 5 No 5 Taylor Introduction Evaluation of disease activity and structural damage to joints in rheumatoid arthritis (RA) is essential in...

Ngày tải lên: 09/08/2014, 01:23

... Combination Therapy Trial Group: Delay to institution of therapy and induc- tion of remission using single-drug or combination-disease- modifying antirheumatic drug therapy in early rheumatoid arthritis. ... 9-month RCT of hydrox- ychloroquine versus placebo in early RA. Three years after the study ended, early DMARD therapy still resulted in less pain and disability. The report by Ve...

Ngày tải lên: 09/08/2014, 01:23

... 277:22959-22965. 21. Pushkarsky T, Zybarth G, Dubrovsky L, Yurchenko V, Tang H, Guo H, Toole B, Sherry B, Bukrinsky M: CD147 facilitates HIV-1 infec- tion by interacting with virus-associated cyclophilin A. Proc Natl ... metalloproteinases-1 (RA TIMP-1) and blank contrast (RA blank) in the lining and sublining layers in RA synovium (× 400). The bottom two images show the expression of C...

Ngày tải lên: 09/08/2014, 06:23

... arthritis (RA). RA is an inflammatory disease involving joints and other systems including salivary glands. To assess NO production in RA patients, we compared levels of serum, urine, and salivary nitrite and ... nitrotyrosines in serum and synovial fluid from patients with active RA, but not in serum from controls. In the present study, we assessed NO production in vivo by measurin...

Ngày tải lên: 09/08/2014, 08:22

... metalloproteinases and suppressed extracellular matrix synthesis, induction of catabolic cytokines/chemokines and proinflammatory inducible enzymes, and activation of NF-κB signaling pathway. Thus, ... to the study of chondrocyte biology on proinflammatory stimulus [19]. Contemporary studies on alginate culture showed that expanded chondrocytes cultured in alginate retain chondro- cyte gen...

Ngày tải lên: 09/08/2014, 10:22

... 58:371-383. 23. Kochi Y, Yamada R, Kobayashi K, Takahashi A, Suzuki A, Sekine A, Mabuchi A, Akiyama F, Tsunoda T, Nakamura Y, Yamamoto K: Analysis of single-nucleotide polymorphisms in Japanese rheumatoid ... 2004, 5:151-157. 3. Stastny P: Mixed lymphocyte cultures in rheumatoid arthritis. J Clin Invest 1976, 57:1148-1157. 4. Korendowych E, Dixey J, Cox B, Jones S, McHugh N: The Inf...

Ngày tải lên: 09/08/2014, 10:23

... however, and in the event they suffered a RA worsen- ing or a flare up they were probably switched to another DMARD, instead of using gold as an add-on therapy. Regarding cyclosporin A treatment, ... were used in combination clearly changed during follow-up. In 2000, the drugs most fre- quently combined with MTX were antimalarials and gold salts, followed by sulfasalazine and cyclospori...

Ngày tải lên: 09/08/2014, 13:22

... in arthritis as well. Interestingly, the wnt proteins, which have been described as regulating neurotrophin expression [29], have recently also Figure 4 NGF staining by flow cytometryNGF staining ... enhancing chemotaxis and production of superoxide by neutrophils [22]. NGF is also involved in humoral immune responses by acting as an autocrine survival factor maintaining the viability o...

Ngày tải lên: 09/08/2014, 14:21

... [Fig 1 (4)]. In some instances, there were remodeling lines which were deeply stained with hematoxylin. Immunohistochemically, S-100 protein-positive products were detected in the cytoplasm of ... reversal line indicated by deeply-stained hematoxylin structure with osteoclasts and osteoblasts. This finding suggests that bone formation occurred over a long period of time. In conc...

Ngày tải lên: 08/08/2014, 16:23