Báo cáo y học: "Lack of association or interactions between the IL-4, IL-4Rα and IL-13 genes, and rheumatoid arthritis" pptx

... marker association analysis of IL-4, IL-13 and IL- 4R SNPs with RA susceptibility We successfully genotyped SNPs in IL-4, IL-13 and IL-4R genes, tagging one block for IL-4 and one block for IL-13. ... SNPs, the haplotypes of the markers of the two genes were analyzed separately. Haplotype analysis of IL-13 predicted four haplotypes, all of which had a freq...

Ngày tải lên: 09/08/2014, 10:23

... to the acquisition of data. HRG contributed to the revision of the draft of the manuscript. GDK contributed substantially to the conception and design of the project and to the revision of the ... anti-inflammatory drugs/cyclooxygenase II inhibitors; RA, rheumatoid arthritis; RF, rheumatoid factor; Table 1 (Continued) Demographics and clinical and labora...

Ngày tải lên: 09/08/2014, 01:22

... evaluated the patients, and AG coordinated the study and participated in its design and analysis. Acknowledgements The authors thank sample donors for their collaboration. They thank also Yolanda ... Spain). JR-L is the recipient of a scholar- ship of the National Program for the Training of University Professors of the Spanish Ministry of Education. AG was supp...

Ngày tải lên: 09/08/2014, 07:20

... University of Science and Technology in Wuhan City, Hubei province, China. Participa- tion was voluntary. Detection of mannose-binding lectin gene polymorphisms Polymorphisms in codons 54 and 57 of the ... HS and XFH contributed to the acquisi- tion of clinical data. ZDY contributed to the statistical analyses. Acknowledgements We are indebted to the staff in HWW's...

Ngày tải lên: 09/08/2014, 08:22

... anti-inflammatory drugs/cyclooxygenase II inhibitors; RA, rheumatoid arthritis; RF, rheumatoid factor; Table 1 (Continued) Demographics and clinical and laboratory characteristics of the glucocorticoid ... Resistance [36], in order to ensure that the definition used would not affect the outcome of this study. The lack of any association between GC expo- sure and...

Ngày tải lên: 09/08/2014, 13:22

... Carmen Delport (study coordinator) and her team, for the help with collecting blood samples; Ms Alicia Evans and pharmacology laboratory team for the sample preparation and analysis; and to the patients ... al.: Lack of association between stavudine exposure and lipoatrophy, dysglycaemia, hyperlactataemia and hypertriglyceridaemia: a prospective cross sectional study....

Ngày tải lên: 10/08/2014, 05:21

... study examined this relationship for inhalant allergens and found a correlation between the severity of clinical symptoms and the degree of skin test reactivity (assessed by the size of the Original ... Nittner-Marszalska and col- leagues found that for patients with allergy to the venom of insects of the order Hymenoptera, there was no correlation between the...

Ngày tải lên: 08/08/2014, 21:20

... sequences of the variable regions of the cloned heavy and light chains of a human anti- cytomegalovirus antibody reveal a striking similarity to human monoclonal rheumatoid factors of the Wa idiotypic ... frequency of these antibodies in normal populations, those published reports all find a frequency of between 0 and 3%, similar to those reported in the present st...

Ngày tải lên: 09/08/2014, 06:22

... 2), as well as their history and geography. The Spanish population in particular is distinct from the others; for example, the frequency of the common allele, Asp13 (D13), in the Spanish control ... ratios exceed 1. Given that the deviation of the odds ratio is random, the probability for its Letter Replication of association of the D-repeat polymorphism in aspor...

Ngày tải lên: 09/08/2014, 08:22

... circumvent the rapid inactivation and renal clearance of GLP-1 is therefore an important step toward applying them therapeutically [5, 6]. Type 2 diabetes is characterized by insulin re- sistance and ... inactivation and renal clearance of GLP-1. Studies have reported N-terminus is very important for the biological activity of GLP-1, and for globular adi- ponectin, th...

Ngày tải lên: 25/10/2012, 11:10