Báo cáo y học: "Cartilage degradation is fully reversible in the presence of aggrecanase but not matrix metalloproteinase activity" pdf

... measuring sulphated glycosaminoglycans (S-GAGs) are available, these assays do not distinguish between synthesis and degradation of the pro- teoglycans [19]. Furthermore, they do not distinguish ... level of IGF-induced collagen II synthesis after 11 days of cytokine treatment and no IGF-induced colla- gen II synthesis after 17 days of cytokine treatment (Figure 2b). Interesti...

Ngày tải lên: 09/08/2014, 10:23

... lineages. Keywords: a s1 -casein gene; allelic recombination; genetic polymorphism; g oat milk. Caseins comprise the main protein fraction of ruminant milk. They are encoded by four tightly linked ... chain, as compared with the F variant; (c) the deoxycytidyl phosphate residue at position 2 3 in the 9th exon of the A alle le, which is deleted in the F allele, is mutat...

Ngày tải lên: 22/02/2014, 04:20

... selectively [20]. In that study a highly specific neutralizing antibody against IL-8 was administered in several types of acute inflammatory disease, including lipopolysaccharide/IL-1 induced arthritis. ... homeostatic chemokines are involved in maintaining normal leucocyte traffic and cell compartmentalization in lymphoid tissues under non-inflammatory conditions [2]. Most chemokin...

Ngày tải lên: 09/08/2014, 01:23

... Ltd 128 Arthritis Research & Therapy June 2005 Vol 7 No 3 Hall ushers of true disease-modifying therapy in this intractable disease. Competing interests FCH is supported by the Arthritis Research ... processes underlying RP and PAH contribute to the familiar pattern of skin, renal and gastrointestinal pathology. The emergence of effective and conveniently administered ther...

Ngày tải lên: 09/08/2014, 06:23

... pathogenesis of RA. Introduction Synovial tissue from healthy individuals consists of a single layer of synovial cells without infiltration of inflammatory cells. In rheumatoid synovial tissue, lymphocytes ... biology. Role of synovial fibroblasts in the pathogenesis of rheumatoid arthritis. Arthritis Res 2000, 2:361-367. 29. Yamanishi Y, Firestein GS: Pathogenesis of rhe...

Ngày tải lên: 09/08/2014, 08:23

... quality control program run by the Korean Society of Laboratory Medicine [3]. In 1999 and 2007, reports of antinuclear antibody test using the IT-1 cell line on 208 and 588 systemic lupus erythematosus (SLE) ... passed inspection by the Korea Food and Drug Administration in South Korea. Currently, IT-1 is being used under the name of the autoimmune target (AIT) test and...

Ngày tải lên: 09/08/2014, 14:21

... Despite the clearance of the AIT test by the South Korea Food and Drug Administration, to the best of our knowledge this test is not widely used as a screening method – neither is it approved by the ... assay, and then used these sera to determine the positivity and staining patterns in the AIT test. This method raises concerns because it is generally known that im...

Ngày tải lên: 09/08/2014, 14:22

... for the first time. The outcomes of this trial are therefore likely t o strongly influence practice guidelines and clinical care in this area. This trial will be limited by its inability to blind ... apophysis [1-3]. This condition is characterised by pain exp erienced near the lower poster- ior aspect of the calca neus in cl ose proximity to the attachment of the Achi...

Ngày tải lên: 10/08/2014, 21:24

... covariance matrix of the interference. Unfortunately, the statistics of the interference may fluctuate rapidly over a short distance, limiting the availability of homogeneous secondary data. The resulting errors ... techniques [13–16]. The approach is to adaptively minimize the interference power while maintaining the array gain in the direction of the signal....

Ngày tải lên: 21/06/2014, 05:20

... chaperonin- containing t-complex polypeptide 1 (CCT), also called TriC, assists in the folding of actin and tubulin in the presence of ATP in vitro and binds newly synthesized actin and tubulin in ... Kubota, H., Hynes, G. & Willison, K. (1995) The chaperonin containing T-complex polypeptide 1 (TCP-1). Multisubunit machinery assisting in protein folding and assembly...

Ngày tải lên: 08/03/2014, 09:20