Báo cáo y học: "Expression of novel extracellular sulfatases Sulf-1 and Sulf-2 in normal and osteoarthritic articular cartilage" pdf
... immunohistochemistry, and Western blotting. Aging and OA are closely linked. To address Figure 2 Localization of Sulf-1 and Sulf-2 in normal cartilageLocalization of Sulf-1 and Sulf-2 in normal cartilage. ... protein extracts from normal and OA cartilage. Figure 6 Sulf-1 and Sulf-2 expression in murine temporomandibular jointsSulf-1 and Sulf-2 expr...
Ngày tải lên: 09/08/2014, 10:23
... Heparin-binding, highly basic regions within the thyroglobulin type-1 repeat of insulin-like growth factor (IGF)-binding proteins (IGFBPs)-3–5, and -6 inhibit IGFBP-4 degradation. Endocrinology ... metalloproteinase; metzincin; insulin-like growth factors; IGF binding proteins; pregnancy proteins. Insulin-like growth factors (IGF)-I and -II are established regulators of growth in ma...
Ngày tải lên: 31/03/2014, 21:21
... N-terminus of globular adiponectin and the C- terminus of GLP-1-A through the linker, which could make the N-terminus of GLP-1-A and the C-terminus of gAdiponectin be free and interact productively ... and may be a promising agent that can treat type 2 daibetes by improving both insulin resistance and insulin secretion deficiency. However, we only ob- served the glucose...
Ngày tải lên: 25/10/2012, 11:10
Báo cáo y học: "Expression of hMSH2 protein of the human DNA mismatch repair system in oral lichen planus"
... epithelial layers of reticular subtype of oral lichen planus patient (streptavidin-biotin amplified system, x 400). Figure 2. Increased labelling of hMSH2 protein in basal and intermediate ... omission of the primary or the secondary antibody or primary incubation in the presence of non-immunized rabbit serum instead of the primary antibody. Cell quantification and...
Ngày tải lên: 03/11/2012, 09:54
Báo cáo Y học: Expression of the V-ATPase proteolipid subunit of Acetabularia acetabulum in a VMA3-deficient strain of Saccharomyces cerevisiae and study of its complementation pdf
... [10]. The YN11 strain was derived from YPH499 strain, and YN45 strain was prepared by the use of YN11 and BJ5458 strains. Preparation of AACEVAPD1 –6 5 0 RACE and 3 0 RACE products of the respective ... complementability of the group 2 proteins for the yeast vma3-mutant. A comparison of the structures, especially in the four hydrophobic domains (underlined sequences in Fig...
Ngày tải lên: 08/03/2014, 23:20
Báo cáo Y học: Expression of uncoupling protein-3 in subsarcolemmal and intermyofibrillar mitochondria of various mouse muscle types and its modulation by fasting docx
... Kuhne, Pierre Flandin, Jean-Paul Giacobino and Patrick Muzzin Department of Medical Biochemistry, Faculty of Medicine, University of Geneva, Switzerland Uncoupling protein-3 (UCP3) is a mitochondrial inner- membrane ... density of UCP3 protein (i.e. the intensity of the signal expressed per mg of proteins) was similar in the SS mitochondria of the two glycolytic muscles, tib...
Ngày tải lên: 24/03/2014, 04:21
Báo cáo Y học: Expression of the aspartate/glutamate mitochondrial carriers aralar1 and citrin during development and in adult rat tissues docx
... by a liver-specific deficiency in argininosuccinate synthetase (ASS). In the liver, the AGC plays an important role in the urea cycle by providing aspartate for incorporation into argininosuccinate ... values, in atria and ventricles, respectively). (D) Immunoblotting of increasing amounts of recombinant citrin and aralar1. Known amounts (as indicated) of bacterially expressed...
Ngày tải lên: 24/03/2014, 04:21
Báo cáo Y học: Expression of glucose transporter-2, glucokinase and mitochondrial glycerolphosphate dehydrogenase in pancreatic islets during rat ontogenesis potx
... secretion of insulin. Bearing this in mind, we determined the activities of citrate synthase (an enzyme of the Krebs cycle re¯ecting the number of mitochondria [10]), succi- nate dehydrogenase and cytochrome ... groups, whereas in liver it was only present in adults and 20-day-old suckling rats. In fetal islets, GLUT-2 and glucokinase pro- tein and their mRNA increased...
Ngày tải lên: 31/03/2014, 15:20
Báo cáo Y học: Expression of the uncoupling protein 1 from the aP2 gene promoter stimulates mitochondrial biogenesis in unilocular adipocytes in vivo potx
... Hora  kova  1 , Ivo Syrovy  1 , Saverio Cinti 2 and Jan Kopecky  1 1 Department of Adipose Tissue Biology and Center for Integrated Genomics, Institute of Physiology, Academy of Sciences of the Czech ... development of obesity by both, increasing energy expenditure and d ecreasing in situ lipogenesis. In order to further analyse consequences of respiratory uncoupling...
Ngày tải lên: 31/03/2014, 15:20
Báo cáo Y học: Toxicity of novel C-terminal prion protein fragments and peptides harbouring disease-related C-terminal mutations pdf
... PrP c . This interaction via binding to the hydrophobic domain of PrP c then inhibits the toxicity of the C-terminus. The normal N-terminal domain of the C-terminal cleavage product of PrP c is ... fragment of this protein can be detected nor- mally in brain [15] and the N-terminal fragment, retaining the copper binding region can be purified by metal affinity chromatography fro...
Ngày tải lên: 31/03/2014, 23:20