Báo cáo y học: "High mobility group box-1 protein as a tumor

Báo cáo y học: " High-mobility group box protein 1 (HMGB1): an alarmin mediating the pathogenesis of rheumatic disease." docx

... and systemic infection. Crit Care 2007, 11:R122. 70. Abeyama K, Stern DM, Ito Y, Kawahara K, Yoshimoto Y, Tanaka M, Uchimura T, Ida N, Yamazaki Y, Yamada S, Yamamoto Y, Yamamoto H, Iino S, Taniguchi ... is a highly con- served nuclear protein that is a prototype for a unique class of proinflammatory mediators called alarmins. As a group, alarmins display distinct intracellu...

Ngày tải lên : 09/08/2014, 10:23

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Báo cáo y học: "High mobility group box-1 protein as a tumor necrosis factor-independent therapeutic target in rheumatoid arthritis." ppsx

... Kawahara K, Yone K, Hashiguchi T, Yamakuchi M, Goto M, Inoue K, Yamada S, Ijiri K, Matsunaga S, Nakajima T, Komiya S, Maruyama I: High mobility group box chromosomal protein 1 plays a role in ... Qureshi AR, Gallowitsch- Puerta M, Patel NB, Huston BJ, Chavan S, Rosas-Ballina M, Gregersen PK, Czura CJ, Sloan RP, Sama AE, Tracey KJ: Cholin- ergic anti-inflammatory pathway activity and...

Ngày tải lên : 09/08/2014, 10:23

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Báo cáo y học: " Monocytes are essential for inhibition of synovial T-cell glucocorticoid-mediated apoptosis in rheumatoid arthritis" docx

... gated as CD3 + cells, and apoptosis was quantified as the mean percentage of Annexin V and 7- AAD + cells from the total number of gated cells. Statistical analysis Statistical analysis was ... and incubated with Annexin V and 7-amino-actinomycin D (7-AAD) as specified by the manufacturer (559763; BD Biosciences) and analyzed by flow cytometry. T cells were gated as CD3 + cells, an...

Ngày tải lên : 09/08/2014, 01:22

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Báo cáo y học: "Decreased response to IL-12 and IL-18 of peripheral blood cells in rheumatoid arthritis" doc

... Morita Y, Yamamura M, Kawashima M, Harada S, Tsuji K, Shibuya K, Maruyama K, Makino H: Flow cytometric single-cell analysis of cytokine production by CD4+ T cells in synovial tissue and peripheral ... (data not shown). The finding was similar for patients receiving methotrexate. Preliminary results appear to indicate that PBMCs from RA patients taking Available online http:/ /arthritis- re...

Ngày tải lên : 09/08/2014, 01:23

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Báo cáo y học: "Expression and functional properties of antibodies to tissue inhibitors of metalloproteinases (TIMPs) in rheumatoid arthritis" docx

... Yoshihara Y, Nakamura H, Obata K, Yamada H, Hayakawa T, Fujikawa K, Okada Y: Matrix metalloproteinases and tissue inhibitors of metalloproteinases in synovial fluids from patients with rheumatoid ... metalloproteinases and their inhibitors to cartilage proteoglycan and collagen turnover and inflammation as revealed by analyses of synovial fluids from patients with rheumatoid arthri...

Ngày tải lên : 09/08/2014, 06:23

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Báo cáo y học: "Monocytes are essential for inhibition of synovial T-cell glucocorticoid-mediated apoptosis in rheumatoid arthritis" pdf

... 2005, 52:61-72. 18. Makrygiannakis D, af Klint E, Catrina SB, Botusan IR, Klareskog E, Klareskog L, Ulfgren AK, Catrina AI: Intraarticular corticosteroids decrease synovial RANKL expression in inflammatory arthritis. Arthritis ... Makrygiannakis, Shankar Revu, Petra Neregård, Erik af Klint, Omri Snir, Cecilia Grundtman and Anca Irinel Catrina Department of Rheumatology, Karolinska Unive...

Ngày tải lên : 09/08/2014, 13:22

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Báo cáo y học: "The Ras guanine nucleotide exchange factor RasGRF1 promotes matrix metalloproteinase-3 production in rheumatoid arthritis synovial tissue" doc

... displays in vitro and in vivo exchange activity against H-Ras [28], as well as against the Rho family GTPase Rac [29,30]. RasGRF1 activity can also be regulated by protease-dependent post-translational ... expressed as a truncated protein in fibroblast-like synoviocytes. (a) Immunoblot analysis of Ras guanine nucleotide-releasing factor 1 (RasGRF1) in rheumatoid arthriti...

Ngày tải lên : 09/08/2014, 14:22

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Báo cáo y học: " High sensitivity C-reactive protein is associated with lower tibial cartilage volume but not lower patella cartilage volume in healthy women at mid-life" pdf

... Central and Eastern Clinical School, Monash University, Alfred Hospital, Prahran, Victoria Australia 2 The Jean Hailes Foundation, Clayton, Victoria Australia 3 Department of Epidemiology and ... immunoturbidimetric assay performed on a Hitachi 917 analyzer (Boehringer Mannheim, Friedrich-Ebert-Str. 10068167 Mannheim, Germany). The assay range was 0.1 to 20 mg/l, with intra-assay coefficie...

Ngày tải lên : 09/08/2014, 10:23

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Báo cáo y học: " High avidity autoreactive T cells with a low signalling capacity through the T-cell receptor: central to rheumatoid arthritis pathogenesis" pot

... SR, Chida AS, Bauter MR, Shafiq N, Seweryniak K, Maggir- war SB, Kilty I, Rahman I: Cigarette smoke induces proinflammatory cytokine release by activation of NF-kappaB and posttranslational modifications ... NF-kappa B as a therapeutic target in autoimmune disease. Curr Opin Ther Targets 2007, 11:111-122. 51. O’Sullivan B, Thomas HE, Pai S, Santamaria P, Iwakura Y, Steptoe RJ,...

Ngày tải lên : 09/08/2014, 10:23

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Báo cáo y học: "Differential expression of chemokine receptors on peripheral blood B cells from patients with rheumatoid arthritis and systemic lupus erythematosus" ppsx

... Most strikingly, an increase in the percentage of CXCR3 hi naive B cells, a finding characteristic for patients with RA, was observed. This increase was seen also under anti-TNF-α therapy and to ... cells within the analyzed group were com- pared in a hierarchic statistic analysis, using Kruskal–Wallis and the nonparametric Mann–Whitney U test. Correlations were determined by Spear...

Ngày tải lên : 09/08/2014, 06:23

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Báo cáo y học: "High mobility group box-1 protein as a tumor necrosis factor-independent therapeutic target in rheumatoid arthritis " ppsx

Báo cáo y học: " High-mobility group box protein 1 (HMGB1): an alarmin mediating the pathogenesis of rheumatic disease." docx

Báo cáo y học: "High mobility group box-1 protein as a tumor necrosis factor-independent therapeutic target in rheumatoid arthritis." ppsx