Báo cáo y học: "Discontinuation rates in clinical trials in musculoskeletal pain: meta-analysis from etoricoxib clinical trial reports" ppt

... discontinuations from being a useful measure, perhaps as much or more so in clinical practice as in clinical trials, although discontinuations have been mentioned previously in clinical trials in ... trialsGastrointestinal discontinuations with etoricoxib and placebo in individ- ual trials. Yellow symbols are trials lasting 4 to 12 weeks; red symbols are trials of...

Ngày tải lên: 09/08/2014, 10:23

... increased resistance to musculoskeletal micro-injury, psychologically based increase in pain threshold, innately high pain threshold influencing decision to exercise vigorously, or other psycho- logical ... pain in women over 65 years of age and observed wide- spread musculoskeletal pain. Conclusion The primary finding from this investigation is that while pain does increase with ag...

Ngày tải lên: 09/08/2014, 07:20

Ngày tải lên: 13/08/2014, 18:21

... cyst. It is likely that lack of adequate intracranial cushioning in the presence of an intracranial arachnoid cyst may result in injury not only to ipsilateral but also to contralateral bridging ... may result from inadequate intracranial cushion- ing provided by the arachnoid cyst, which makes both ipsilateral and contralateral bridging veins prone to injury. It is important to identif...

Ngày tải lên: 11/08/2014, 20:20

... very real chance of the chest x-ray being completely normal, serial films may also be of use to identify any evolving pathology [13]. Findings may include: cardiac silhouette may be unu- sually ... accompanying images. A copy of the written consent is available for review by the Editor -in- Chief of this journal. Acknowledgements This paper did not receive any grant or funding from any agen...

Ngày tải lên: 13/08/2014, 23:21

... 'When everything is confused, I feel that way inside', which was originally a Reality Testing item, showed higher factor loading for the first factor in this study, which was interpreted ... Identity Diffusion than of Reality Testing. The present study employed only students. They tended to be young and may be well functioning and different from a population of patients with per...

Ngày tải lên: 08/08/2014, 23:21

... poor clinical response, suggesting that their RA was not much driven by TNF-α activity alone but probably by other cytokines or mechanisms. The heterogeneity in these patterns may be explained by higher ... functional assay for TNF-α activity was designed using the ability of RA synoviocytes to produce IL-6 and OPG in response to TNF-α [5]. To isolate synoviocytes, RA synovial tissues w...

Ngày tải lên: 09/08/2014, 06:22

... that in patients with IPEX (immune dysregulation, polyendocrinopathy, enteropathy, X- linked syndrome) [4] or scurfy mice [5] or by means of depletion with anti-CD25 monoclonal antibodies in animal models, ... the paper by Frey and colleagues represents only a minor blink of an eye in the vast Treg literature, but Frey and colleagues introduce a provocative ‘spin’ to their results as th...

Ngày tải lên: 09/08/2014, 06:23

Ngày tải lên: 09/08/2014, 07:20

... BD (according to the International Study Group criteria [12]), were referred to the vascular laboratory within 3 to 5 days after they had their last clinical evaluation to determine clinical disease ... percentage increase in diameter from baseline. After 10 min, a second scan at rest was performed and then nitroglycerin was administered (400 μg sublingual); 5 min later a final scan w...

Ngày tải lên: 09/08/2014, 10:21