Báo cáo y học: "The need for prognosticators in rheumatoid arthritis Biological and clinical markers: where are we now" potx

... underlying disease process. In rheumatology, this variable may be joint Review The need for prognosticators in rheumatoid arthritis. Biological and clinical markers: where are we now? Josef S Smolen 1,2 , ... Pre-analytical and biological variability in circu- lating interleukin 6 in healthy subjects and patients with rheumatoid arthritis. Biomarkers 20...

Ngày tải lên: 09/08/2014, 10:23

... difficulties in weaning from CPB and also a rather high threshold for intraoperati ve IABP insertion. Ninety patients had intraaortic balloon inserted intrao- peratively with a mortality of 33.3%. We attempt ... surg ery in patients having sustained mechanical complications following myocardial infarction, as well as in patients with refractory angina [5-7]. The hospital and als...

Ngày tải lên: 10/08/2014, 10:20

... Sandberg G, Crayton H: Demyelination occurring during anti TNF therapy for inflammatory arthritides. Arthritis Rheum 2001, 44:2862- 2869. 65. Robinson WH, Genovese MC, Moreland LW: Demyelinating ... changes in HAQ-DI (from baseline to 6 and 12 months) were –0.54 in patients who received combination therapy for the entire trial compared with –0.30 in those receiving combination t...

Ngày tải lên: 09/08/2014, 01:22

... recruitment of inflammatory cells, including monocytes and lymphocytes [1]. It has been proposed that the first cells to infiltrate syn- ovial tissue are T lymphocytes, suggesting that they have an ... water for 1 minute, and incubated in PBS for 5 minutes, followed by the addition of 3,3'-diaminobenzidine (Sigma) for 12 minutes. The chromogenic reaction was stopped by imme...

Ngày tải lên: 09/08/2014, 01:24

... media were collected and analyzed for matrix metalloproteinase (MMP) activity by gelatin zymography. (a) Secretion and activation of MMPs in FLS from rheumatoid arthritis (RA) and osteoarthritis ... were analyzed by agarose gel electrophoresis using 1% gel, followed by ethidium bromide staining. Gelatin zymography Gelatin zymography was performed for detection of MMP activity...

Ngày tải lên: 09/08/2014, 07:20

... only extremely rarely present in the Japanese population [8]. Our data are in line with these observations and together implicate that asso- ciation findings should be carefully analyzed in different ... 40 nor cytosine at position 1,400) were detected in any of the individuals tested. This was sur- prising because both positions were highly polymorphic in the original publicati...

Ngày tải lên: 09/08/2014, 07:20

... (ever/never), body mass index at age 20 years and 10 years before interview, level of physical activity at work and during leisure time 10 years before interview, pets in childhood and in adulthood, ... obese 10 years before interview was marginally associated with increased RA risk. Furthermore, having a physically demanding job 10 years before interview was asso- ciated with signi...

Ngày tải lên: 09/08/2014, 08:22

... involved in the disease. Joints are usually assessed for tenderness and swelling, and joint counts are predictive of radiographic changes as well as of long-term morbidity and mortality in RA 28-JC ... disease activ- ity assessment in RA. In this study, we showed that the assessment of joint activity in the feet, beyond assessment of joint activity by the 28-joint coun...

Ngày tải lên: 09/08/2014, 10:20

... H, Hyldstrup L; the TIRA group: Bone loss in unclassified polyarthritis and early rheumatoid arthritis is better detected by digital X-ray radiogrammetry than dual energy X-ray absorptiometry: ... Emery P: Generalized bone loss in patients with early rheumatoid arthritis. Lancet 1994, 344:23-27. 4. Deodhar AA, Brabyn J, Pande I, Scott DL, Woolf AD: Hand bone densitometry in rh...

Ngày tải lên: 09/08/2014, 10:22

... of value for detecting and monitoring bone erosions in RA. The sensitivity to change is not yet established, however, and CT is disfavored by using ionising radiation and by the inability to visualise ... erosions difficult, and nutri- tive foramina may also resemble erosions [28]. This may, at least partly, explain the lower sensitivity and accuracy in this wrist joint study...

Ngày tải lên: 09/08/2014, 10:23