Báo cáo y học: "Mechanisms of oral tolerance revisited" pps

... induction of oral tolerance [1,7,8]. However, although the combined effects of tryptophan starvation and tryptophan catabolites may contribute to the induction of CD4 + CD25 + Treg cells by IDO [9], ... mice. Functionally, they inhibit collagen type II-specific T cell proliferation and pro-inflammatory Th1 cytokine production, and more importantly, induce the generation of collage...

Ngày tải lên: 09/08/2014, 10:23

... domain of receptors (receptor tyrosine kinases) or as cytosolic enzymes (nonreceptor tyrosine kinases). The src family of nonreceptor tyrosine kinases has been implicated in the control of exocytosis ... primary, secondary, and tertiary granule release. 54 Inhibition of VAMP- 7 by low concentrations of specific anti-VAMP-7 antibody prevented the release of myeloperoxi- dase, lac...

Ngày tải lên: 08/08/2014, 21:20

... Chemistry, Physiology, Phar- macology, Pathology, Experimental and Clinical Investiga- tions. The University of Chicago Press; 1939. 36. Urist RM: Induced systemic hypersensitivity: Selye's ... context. The purpose of this study is to compare the prevalence of rickets, vitamin D supply, and allergy prevalence at 50-year intervals by means of a retrospective analysis of the lit...

Ngày tải lên: 08/08/2014, 21:20

... formation, presenting as ankylosing enthesopathy and leading to bony spurs, syndesmophytes, enthesophytes and eventually joint or spine ankylosis, are hallmark signs of these diseases. This process of ankylosis contributes ... in patients with ankylosing spondylitis. Arthritis Rheum 2008, 58: S945-S946. 46. Fukui N, Zhu Y, Maloney WJ, Clohisy J, Sandell LJ: Stimulation of BMP-2 express...

Ngày tải lên: 09/08/2014, 13:22

... localized in the mammalian eye including the human eye [5]. In fact, melatonin is produced by many structures of the eye including the lens [6], the iris, the ciliary body [7] and the lacrimal glands ... study by Emser and colleagues [24] showed that oral administration of 10 mg of melatonin induces a cone response ERG decline in human. Because the latter study used only a single inte...

Ngày tải lên: 10/08/2014, 09:20

... for the setting of the length of periods of activity and inactivity within cells. Many years of research by a dedicated team of scientists culminated in the discovery of this protein [2]. It is ... in the physiology and behaviour of animals. Some of these neuroendocrine pathways are necessary for the regulation of particular overt seasonal responses, though they may not be d...

Ngày tải lên: 10/08/2014, 09:20

... of oral diseases. Her current work is in radiographic analysis of odontogenic tumors. Ricardo Santiago Gomez, DDS MS PhD, is Professor in Oral Pathology and Director of School of Dentistry, ... controls consisted of omission of the primary or the secondary antibody or primary incubation in the presence of non-immunized rabbit serum instead of the primary antibody. Ce...

Ngày tải lên: 03/11/2012, 09:54

... IFN- γγ by lymphocytes of orally tolerized mice To examine the effect of oral CII administration on the activity of immune cells, we measured the production of IL-10 and TGF-β by mononuclear lymphocytes ... of peripheral tolerance in an orally tolerized mouse model of arthritis. Our findings indicate that the serum levels of pro- inflammatory and anti-inflammatory IgG subtyp...

Ngày tải lên: 09/08/2014, 01:23

... contributing data having quality scores of 3 or more out of the maximum of 5. For efficacy analysis, this level of reporting quality is not likely to suffer bias associated with lack of randomisation or ... non-malignant pain: systematic review of randomised trials of oral opioids R Andrew Moore and Henry J McQuay Pain Research and Nuffield Department of Anaesthetics, Unive...

Ngày tải lên: 09/08/2014, 06:23

... erythematosus (SLE) consistently show an ordered appearance of typical auto-antibodies in the serum of individuals [1-4]. With time the fine specificity of the antibody response initially focused against ... assays To study the natural T-cell reactivity occurring in unprimed lupus-prone mice, MRL/lpr mice were bled at weeks 8, 10, 12 and 14, and lymphocytes were purified by density sepa...

Ngày tải lên: 09/08/2014, 10:21