Báo cáo y học: "Characterisation of the cannabinoid receptor system in synovial tissue and fluid in patients with osteoarthritis and rheumatoid arthritis" pdf
... simply reflect the level of synthesis/release and
catabolism of endocannabinoids and entourage compounds
in the synovium. The source of the endocannabinoids present
in the synovium and synovial fluid ... Representative
micrographs of this grading system are presented in Figure 1.
Quantification of inflammatory cytokines in synovial
fluid
Cytokine pr...
... detected interferon (IFN)-γ staining but no interleukin (IL)-4 staining. Mul-
tiplex cytokine assay was used to analyse the cytokine profile of three T-cell line supernatants. (b) An excess of Th1 ... al.
Page 6 of 9
(page number not for citation purposes)
Cell line cytokine profile
We were interested in comparing the Th1 and Th2 cytokine
secretion profile of CI-specific cell...
... member of the Hsp70 family
and promotes the folding and assembly of protein by
recognizing unfolded polypeptides and inhibiting intra-
and intermolecular aggregation [17]. To investigate the
role of ... CRT
have been described as being necessary to the folding and
oligomeric assembly of various glycoproteins [17].
To study the role of CNX and CRT in the fol...
... RA.
Introduction
Rheumatoid arthritis (RA) is a chronic inflammatory disease
characterized by synovial lining hyperplasia and sublining infil-
tration of inflammatory cells [1]. Fibroblast-like synoviocytes
(FLSs) ... in
rheumatoid arthritis synoviocytes
Deepa R Hammaker
1
, David L Boyle
1
, Tomoyuki Inoue
2
and Gary S Firestein
1
1
Division of Rheumatology, Allergy and Im...
... study was to deter-
mine the reliability of the TekScan MatScan
®
system in
assessing plantar forces and pressures during level bare-
foot walking using a test-retest analysis of thirty healthy
asymptomatic ... Zammit G, Landorf K, Handley C, Elzarka A, Deluca J:
Efficacy of intra-articular hyaluronan (Synvisc(R)) for the treatment of
osteoarthritis affecting the firs...
... correlating with the findings of the SF-36 [1].
Based on this and the observational findings of this
study, the MYMOP2 has potential as a clinically useful
tool to assess chiropractic care in terms of ... objective was to investigate the
validity of the MyMOP2 instrument to detect a change
in well-being of patients attending the RMIT chiroprac-
tic teaching c...
... huge
risks and acted with great bravery to return to the clinic
and to obtain their medication refills.
▪ Patients really surprised us. They walked distances, they
ran away, they tried again, they came ... University School of Medi-
cine and Moi Teaching and Referral Hospital (Eldoret,
Kenya) and the Institutional Review Board of the Indiana
University School of Medi...
... of idiopathic cyclic edema was based on a clinical
history and fluid retention throughout the day, in particular difficulty in removing rings
on waking in the morning which improves later in ... The lack of specific clinical and
laboratory studies hinders research on cyclic edema
and the dissemination of information on this disease.
The fact that it is idiop...
... the cor-
responding tetrazine 6, which in turn reacts with a mixture of the dansyl derivative and the N-ethyl-diisoproylamine
and the dansyl sulfamidoethylamine to the tetrazine product 7 linked ... glycine’s
N-terminus, as originally described by Nielsen in the
protocols for the synthesis of the peptide nucleic acid
(PNA) backbone [29, 30].
We synthesized a...
... obtund pain
of needle insertion including infiltration analgesia and
EMLA patch. Local anesthetics themselves may pro-
duce pain on injection and many anesthetists are un-
sure that infiltration ... venous canulation could decrease
the incidence and severity of pain associated with
venipuncture in adult patients.
7
In another study by Gupta et al the efficacy of
....