Báo cáo y học: "Systemic TNF blockade does not modulate synovial expression of the pro-inflammatory mediator HMGB1 in rheumatoid arthritis patients – a prospective clinical study" ppt
Báo cáo y học: "Systemic TNF blockade does not modulate synovial expression of the pro-inflammatory mediator HMGB1 in rheumatoid arthritis patients – a prospective clinical study" ppt
... No 2 Research article Systemic TNF blockade does not modulate synovial expression of the pro-inflammatory mediator HMGB1 in rheumatoid arthritis patients – a prospective clinical study Erik Sundberg 1,2 , ... 3 Change of HMGB1 synovial mRNA expression before and after inflixi-mab therapyChange of HMGB1 synovial mRNA expression before a...
Ngày tải lên: 09/08/2014, 10:23
Báo cáo y học: "High synovial expression of the inhibitory FcγRIIb in rheumatoid arthritis" ppsx
... synovial biopsies. FcγRIIb staining was observed in the synovial lin- ing and sub-lining layers, perivasculary and inside lymphocyte infiltrates (e). (d) No staining of the RA synovium was observed ... were then washed in 1% BSA in PBS and a phycoeryth- Table 1 Characteristics of patients Patient Category Diagnosis RF Sex/age Duration of disease Therapy 1 Early RA RA...
Ngày tải lên: 09/08/2014, 10:20
Báo cáo y học: " Extracellular heat shock protein 70 inhibits tumour necrosis factor-α induced proinflammatory mediator production in fibroblast-like synoviocytes" doc
... suppres- sion of MAPK pathways. Apart from the MAPKs, NF-κB is another key regulator of proinflammatory mediator expression and plays an important role in the induction of inflammatory cytokines in primordial mesenchymal ... Miyazawa K, Mori A, Miyata H, Akahane M, Ajisawa Y, Okudaira H: Regulation of interleukin-1beta-induced interleukin-6 gene expression in human f...
Ngày tải lên: 09/08/2014, 10:23
Báo cáo y học: "T cell Activation does not drive CD4 decline in longitudinally followed HIV-infected Elite Controllers" docx
... University Health Centre, Montréal, Québec, Canada Full list of author information is available at the end of the article Kamya et al. AIDS Research and Therapy 2011, 8:20 http://www.aidsrestherapy.com/content/8/1/20 © ... assay (bDNA) (Bayer Diagnostics, Tarrytown, NY) with a detection limit of 50 HIV-1 RNA copies/ml of plasma. Cells Blood was obtained by either venipuncture in...
Ngày tải lên: 10/08/2014, 05:22
Tài liệu Báo cáo Y học: CK2btes gene encodes a testis-specific isoform of the regulatory subunit of casein kinase 2 in Drosophila melanogaster potx
... catalytic activity of a subunit toward calmodulin and for the activation by polybasic compounds. The examination of amino-acid alignment in the acidic region of three Drosophila CK2 regulatory ... protein -A Sepharose, washed and separated by SDS/PAGE. The immunostaining of Western blot was performed by commercially available, high affinity anti-(b-galactosidase) Ig. Anti-(...
Ngày tải lên: 21/02/2014, 15:20
Tài liệu Báo cáo Y học: Electrochemical, FT-IR and UV/VIS spectroscopic properties of the caa3 oxidase from T. thermophilus docx
... oxidases. The heme types incorporated belong to the caa 3 -andba 3 -type cytochrome c oxidases, respectively. The caa 3 -oxidase contains analogous central subunits and catalytic entity to the ... formyl side chain from cytochrome c oxidase from bovine heart [2 7–2 9] reportedtobesensitivetoCN – binding in a characteristic way [27]. In Fig. 4A the spectra in the pre...
Ngày tải lên: 21/02/2014, 15:20
Báo cáo y học: "NF-κB inhibitor dehydroxymethylepoxyquinomicin suppresses osteoclastogenesis and expression of NFATc1 in mouse arthritis without affecting expression of RANKL, osteoprotegerin or macrophage colony-stimulating factor" docx
... emulsion intrader- mally at the base of the tail. After 21 days (day 0), the same amount of the antigen emulsified in the same adjuvant was intradermally injected at the base of the tail as a booster ... translocation and activation of NF-κB by dehydroxymethylepoxyquinomicin. J Biol Chem 2002, 277:24625-24630. 15. Miyajima A, Kosaka T, Seta K, Asano T, Umezawa K, Ha...
Ngày tải lên: 09/08/2014, 10:21
Báo cáo y học: "Differential expression of the FAK family kinases in rheumatoid arthritis and osteoarthritis synovial tissues" doc
... probably as a result of inflammation in RA ST. Focal adhesion kinase (FAK) and proline-rich tyrosine kinase (Pyk)2 are two members of a family of nonreceptor protein tyrosine kinases that are acti- vated ... pFAK reactivity in normal ST lining (arrow) and subsynovial macrophages (arrowhead). (d) The quantification of data obtained from a, b and c. Bars represent the mean...
Ngày tải lên: 09/08/2014, 10:21
Báo cáo y học: "Ultrasonography, magnetic resonance imaging, radiography, and clinical assessment of inflammatory and destructive changes in fingers and toes of patients with psoriatic arthritis" pot
... projection radiography (x-ray), and clinical examination. DIP, distal interphalangeal; MCP, metacarpophalangeal; NA, not applicable; PIP, proximal interphalangeal. Available online http:/ /arthritis- research.com/content/9/6/R119 Page ... the metacarpophalangeal and proximal interphalangeal joints in rheumatoid arthritis: a comparison with magnetic res- onance imaging, conventio...
Ngày tải lên: 09/08/2014, 10:21
Báo cáo y học: "Blood autoantibody and cytokine profiles predict response to anti-tumor necrosis factor therapy in rheumatoid arthriti" pps
... measurements from the single-antigen ELISAs were combined with the measurements from the bead-array cytokine assay for integrated analysis of cytokine and autoan- tibody profiles in baseline samples derived ... read and approved the final manuscript. Additional files The following Additional files are available online: Additional data file 1 Excel file containing a table that...
Ngày tải lên: 09/08/2014, 14:21