Báo cáo y học: "New classification of HLA-DRB1 alleles in rheumatoid arthritis susceptibility: a combined analysis of worldwide samples" docx

... USA) and the help of technical and clinical collaborators from the rheumatoid arthritis international working group, for clinical data management and laboratory typings. The authors are indebted ... summary meta -analysis of allele carrier fre- quencies according to HLA-DRB1 allele classification, in selected samples among the data available from the 13th International Histoc...

Ngày tải lên: 09/08/2014, 10:23

... Kimura Y, Sakata M, Naganawa M, Oda K, Miyatake R, Fujisaki M, Shimizu E, Shirayama Y, Iyo M, Hashimoto K: High occupancy of sigma-1 receptors in the human brain after single oral administration of ... human brain at therapeutic doses, * Correspondence: furuse@asahikawa-rch.gr.jp 1 Department of Psychiatry, Asahikawa Red Cross Hospital, Asah ikawa, Japan Furuse and Hashimoto Annals...

Ngày tải lên: 08/08/2014, 23:21

... instructions. Statistical analysis Statistical analysis was performed using the Statview soft- ware (Abacus Concept Inc., Cary, NC, USA). Means were Table 1 Patient characteristics Characteristic All RA patients ... necrosis factor (TNF) bioactivity in rheuma-toid arthritis (RA) patients and healthy individualsPattern of plasma tumour necrosis factor (TNF) bioactivity in rheuma- t...

Ngày tải lên: 09/08/2014, 06:22

... from a patient with a 1 year history of RA is shown in Figure 1. Finally, animal studies are emerging to clarify the role of the bone marrow as a site of pathology in RA. Marinova- Mutafchieva and ... remain normal. Arthritis Rheum 2004, 50:2094-2102. 21. Tamai M, Kawakami A, Takao S, Uetani M, Arima K, Tanaka F, Fujikawa K, Aramaki T, Iwanaga N, Izumi Y, et al.: Bone marr...

Ngày tải lên: 09/08/2014, 08:23

... fellow phagocytic cells of the monocyte/ macrophage lineage. Their rapid secretion of many factors that are also released by macrophages, lymphocytes and fibroblasts indicates that they can play similar ... Nakagawa I, Kawabata S, Amano A, Ooshima T, Hamada S: Streptococcus pyogenes infection induces septic arthritis with increased production of the receptor activator of the NF-ka...

Ngày tải lên: 09/08/2014, 10:20

... JA: A shift in the balance of inhibitory and activating Fcgamma receptors on monocytes toward the inhibitory Fcgamma receptor IIb is associated with prevention of monocyte activation in rheumatoid ... opportunity to study surface expression of inhibitory and activating FcγRs will lead to enhanced understanding of FcγR-mediated immunopathology in RA. Apart from nonspecific mo...

Ngày tải lên: 09/08/2014, 10:20

... carbohydrate-specific anti- bodies have not yet been systematically investigated in RA, in spite of the fact that hyaline cartilage and synovial fluid contain large amounts of GAGs including HA, ... cartilageDetection of anti-glycosaminoglycan (GAG) antibody binding to the extracellular matrix of hyaline cartilage. Microphotograph (a) shows the binding of rheumatoid arthrit...

Ngày tải lên: 09/08/2014, 13:22

... were admitted to Stavanger University Hospital. We defined severe trauma as a primary diagnosis of traumatic injury and a National Committee on Aeronautics severity of injury or illness index (NACA) ... active as pre-hospital emer- gency physicians regard pre-hospital airway management as challenging and recognise that such procedures likely warrant special training beyond the experie...

Ngày tải lên: 25/10/2012, 09:56

... in analytical scale. The four oligosaccharide fractions were separately pyridylaminated and designated endoH-PA, PNGaseF-PA, PNGaseA-PA and Hyd(HFA)-PA, respect- ively. Analytical anion-exchange ... analysis revealed that the KLH preparation investigated in this study contained about 3.3% (by weight) neutral carbohydrates. N-Acetylglucosamine, N-acetylgalactosamine, galactose, mannose,...

Ngày tải lên: 31/03/2014, 08:20

... suggest that a bacterial ligand of integrin α5β1 may contribute to the aggressive behavior of RA FLSs by inducing the release of pro-inflammatory cytokines and a cartilage-degrading enzyme, such as ... T, Yli-Jama T, Jal- ava J, Vainio O, Toivanen P: Bacterial components in the syno- vial tissue of patients with advanced rheumatoid arthritis or osteoarthritis: analysis wit...

Ngày tải lên: 09/08/2014, 06:22