Báo cáo y học: "Anti-inflammatory effect of antidiabetic thiazolidinediones prevents bone resorption rather than cartilage changes in experimental polyarthritis" pps

... increase in intra-LV dyssynchrony was also demonstrated during pharmacological stress in systolic heart failure patients with normal QRS dura- tion. The prevalence of dyssynchrony was low in ... test, interventricular dyssynchrony Introduction The introduction of cardiac resynchronization therapy has recently renewed the clinical interest in the analysis of...

Ngày tải lên: 05/11/2012, 11:32

... as independent modification of CYP11B2 reaction steps. The combination of functional data and computer modelling of CYP11B2 suggests an indirect involvement of r esidue 147 in the regulation of ... [17–19,41,42]. These stuc tures are mainly located in the C-terminal regions of CYP11B1 and CYP11B2. So far, the role of distinct amino acids of the N-terminal...

Ngày tải lên: 24/03/2014, 03:21

... double-blind, placebo-controlled efficacy and safety study of quetiapine or lithium as monotherapy for mania in bipolar disorder. J Clin Psychiatry 2005, 66:111-121. 66. McElroy SL, Martens BE, Winstanley ... double-blind, randomized comparison of the efficacy and safety of intramuscular injections of olanzapine, lorazepam, or placebo in treating acutely agitated patients di...

Ngày tải lên: 09/08/2014, 01:21

... RT-PCR of the enzymes involved in the synthesis of these mediators (cyclooxygenase-2 (COX-2) and inducible Figure 1 Cytokine circulating levels in mice at the end of treatment in the collagen-induced ... transcriptionally Figure 4 Effect of vasoactive intestinal peptide (VIP) on NFκB binding and IκB degradation in synovial cells from mice with collagen-ind...

Ngày tải lên: 09/08/2014, 06:23

... NH, Kwak JY, Lee YC, Cho YS, Kim HC, Chae YM, et al.: Inhibitory effects of novel E2F decoy oligodeoxynucleotides on mesangial cell proliferation by coexpression of E2F/DP. Biochem Biophys Res Commun 2003, ... stability and binding activity of RNODN and PNODN. (a) Stability of phosphorothionate double-stranded NF-κB decoy oligodeoxynucle- otide (PNODN) and ribbon-type NF-...

Ngày tải lên: 09/08/2014, 08:22

... as changes in plasma osteocalcin concentration (ng/ml) over the study duration (day 21 minus day -1), each animal being used as its own control. Deoxypyridinoline urinary level Urinary deoxypyridinoline ... 10 mg/kg/day of rosiglitazone nor 30 mg/kg/day of pioglitazone (Table 6). In contrast, the deoxypyridinoline/creatinine urinary level remained stable in normal controls but inc...

Ngày tải lên: 09/08/2014, 10:22

... STA-5326 may be merely delaying the onset of EAU rather than decreasing the overall severity of inflamma- tion. However, STA-5326 also decreased inflammation when administered only during the effector ... EAU. Discussion In the present study, we showed that oral administration of the potent IL-12/IL-23 inhibitor, STA-5326, reduces the severity of EAU by clinical...

Ngày tải lên: 09/08/2014, 13:22

... inhibitory peptide on interleukin-1β-induced matrix metalloproteinase production in rheumatoid synovial fibroblasts, and its antiarthritic activity in hTNFtg mice Maung-Maung Thwin 1 , Eleni ... AA, Gopalakrishnakone P: Secretory phospholipase A2 activity in the normal and kainate injected rat brain, and inhibition by a peptide derived from py...

Ngày tải lên: 09/08/2014, 14:22

... based on very small sample sizes and generally conducted within carefully controlled labora- tory type environments. There is currently little under- standing of the effect of lighting conditions ... aim of this study was to quantify the effects of newly developed high correlated colour temperature fluorescent lighting on functioning, well-being and work perfor...

Ngày tải lên: 10/08/2014, 09:20

... during and after cardiac surgery, on patient mortality and morbidity: A systematic review and meta-analysis Kristin K Haga 1* , Katie L McClymont 1 , Scott Clarke 1 , Rebecca S Grounds 1 , Ka Ying ... control, during and after cardiac surgery, on patient mortality and morbidity: A systematic review and meta-analysis. Journal of Cardi...

Ngày tải lên: 10/08/2014, 09:23

... COMM E N TAR Y Open Access Detrimental effect of cardiopulmonary bypass (CPB) on malignant disease Ahmad K Darwazah * , Saleh Shehata Abstract Patients with coronary artery disease associated ... revascularization of the myocardium among patients with malignant disease, may have an effect on dissimination of malignant cells. This was observed among two of our...

Ngày tải lên: 10/08/2014, 09:23

... c-phycocyanin through modulation of tyrosinase expression by upregulation of ERK and downregulation of p38 MAPK signaling pathways Li-Chen Wu 1,2* , Yu-Yun Lin 2 , Szu-Yen Yang 2 , Yu-Ting Weng 2 and Yi-Ting ... activation of ERK. Cell Cycle 2007, 6:3078-3085. doi:10.1186/1423-0127-18-74 Cite this article as: Wu et al.: Antimelanogenic effect of c-phy...

Ngày tải lên: 10/08/2014, 10:20

... Group's intensive care unit physi- cian staffing standard. J Crit Care 2007, 22:89-96. 13. Lipschik GY, Kelley MA: Models of critical care delivery: physi- cian staffing in the ICU. Semin Respir ... variation in organisa- tional characteristics among ICUs reporting compliance with the high intensity physician staffing model [45]. We assigned ICU model structur...

Ngày tải lên: 13/08/2014, 11:23

... may play a role in the reduction in glutamine levels during inflammation. The aim of the present study was to investigate whether glutamine infusion had an effect on the cytokine and WBC response ... cited. Abstract Introduction Glutamine supplementation has beneficial effects on morbidity and mortality in critically ill patients, possibly in part through an at...

Ngày tải lên: 13/08/2014, 11:23

... purpose of this study was to evaluate whether adding low-dose ketamine to a standard morphine sulphate dose improves the pain/nausea scores and hemodynamic parameters compared to morphine sulphate alone ... median and quartiles. Demographic data were ana- lysed using parametric t-test. Pain and nausea scores were analysed using non-parametric test (Mann-Witney) and sed...

Ngày tải lên: 13/08/2014, 23:21