Báo cáo y học: "The role of aldosterone blockade in murine lupus nephritis" pdf

... therapeutic strategies of chronic renal injury: renoprotective effects of aldosterone blockade. J Pharmacol Sci 2006, 100:9-16. 23. Teplitsky V, Shoenfeld Y, Tanay A: The renin-angiotensin system in lupus: physiology, ... [10-12]). Aldosterone also exerts proinflammatory effects in the kidney and other tissues [13,14], such as leuko- cyte infiltration and increased expression...

Ngày tải lên: 09/08/2014, 10:22

... carboxyl group of the a-aminoadipoyl- side-chain of penicillin N (1), with arginines 74 and 75 apparently playing a less important role in side-chain binding. Taken together, the results of this ... ternary com- plex to oxygen binding, thereby initiating catalysis and ensuring coupling of 2-oxoglutarate conversion to prime substrate oxidation. In the case of DAOCS it has been...

Ngày tải lên: 18/03/2014, 01:20

... activity of a glucocorticoid-regulated inflammatory cyclooxygenase. Proc Natl Acad Sci USA 1992, 89:4888-4892. 7. Raskin JB: Gastrointestinal effects of nonsteroidal anti-inflam- matory therapy. ... their role in bone metabolism and repair remains unclear. Review of the evidence To determine the role of COX-2 in bone repair, investiga- tors have studied fracture healing in a...

Ngày tải lên: 09/08/2014, 01:21

... mild dysplasia Spondyloepiphyseal dysplasia, congenital type Spondyloepiphyseal dysplasia, Namaqualand type Spondyloepiphyseal dysplasia, Strudwick type Spondyloepiphyseal dysplasia, various types Spondyloepiphyseal ... Familial spondyloepiphyseal dys- plasia tarda, brachydactyly, and precocious osteoarthritis associated with an arginine 75 →→ cysteine mutation in the pro- collagen type II...

Ngày tải lên: 09/08/2014, 06:22

... Taylor F: Induction of matrix metal- loproteinase-2 and -3 activity in ovine nucleus pulposus cells grown in three-dimensional agarose gel culture by interleukin- 1beta: a potential pathway of ... Immunohistologic study of the ruptured intervertebral disc of the lumbar spine. Spine 1996, 21:235-241. 30. Takahashi H, Suguro T, Okazima Y, Motegi M, Okada Y, Kakiuchi T: Inflammator...

Ngày tải lên: 09/08/2014, 06:22

... cell death induced by pro-inflammatory cytokines. Finally, Yudoh and colleagues showed that HIF-1α is necessary for anaerobic energy generation and proteoglycan synthesis by articular chondrocytes, ... functional inactivation of HIF-1α in the presence of interleukin-1β resulted in a significantly increased number of apoptotic chondrocytes. These in vitro data are in accordance w...

Ngày tải lên: 09/08/2014, 07:20

... declared expectation of only slight knee pain after surgery. In reality, only 43% of the group reported being pain-free at 2 years post operation. The patients were similarly overly optimistic about ... the importance of decreasing pain and increasing function; and expectations of surgery in relation to expected time until full recovery (open answer, in months), expected pain af...

Ngày tải lên: 09/08/2014, 14:22

... redundancy. The analysis of the TE content was done using RepeatMasker software and repbase [56,57]. In the case of C. intestinalis, the analysis of 34,328 intronic sequences was done using the GALAXY ... Transposable elements in Ciona intestinalis TE Total Intronic TEs in introns within RefSeq TEs in introns of non-RefSeq Exons within RefSeq alignments* Exons in non-RefSeq...

Ngày tải lên: 09/08/2014, 20:22

... ‘His-tags’, chains of histidine resi- dues at carboxyl termini of genes in heterologous expression systems [20]. When using carboxy-terminal His-tags in bacterial expression systems it would ... efficiency is affected by a diversity of parameters, including secondary structure of the transcript and its codon usage. Here we examine the effects of codon usage on translation effici...

Ngày tải lên: 09/08/2014, 22:23

... history of dental mutilation in the form of dental chipping and of intentional removal of anterior teeth [ 3]. Early evidence from many archaeolo- gical sites in the Southern Africa was found in ... practice of ebinyo (although carried out ear ly in the life of the child) can impact on the occlusal status in the permanent dentition years later [43]. Patients In the pre...

Ngày tải lên: 10/08/2014, 09:21