Báo cáo y học: " Regulation of Sox9 activity by crosstalk with nuclear factor-κB and retinoic acid receptors" pptx
Báo cáo y học: " Regulation of Sox9 activity by crosstalk with nuclear factor-κB and retinoic acid receptors" pptx
... reduction of Sox9 activity by atRA is inde-
pendent of NF-κB activation.
Binding of protein complexes to the Col2a1 48-bp
minimal enhancer and nuclear Sox9 levels
Since Sox9 activity was decreased by ... NF-κB
nuclear localization by promoting the degradation of IκB [32].
Figure 2
Effects of TNF-α and atRA on Sox9 activityEffects of TNF-α and atRA on...
Báo cáo y học: " Regulation of cardiac microRNAs by serum response factor" potx
... expression of a number of microRNAs. Interestingly, downregulation
of miR-1, miR-133a and upregulation of miR-21 occurred by 7 days of age in these mice, long before the onset of
cardiac hypertrophy, ... no.
GSE23044. Briefly, each pair of wild-type and transgenic
heart samples were labeled with Hy 3 and Hy5 fluores-
cent dyes respectively and hybridized to a miRCURY...
Tài liệu Báo cáo Y học: Regulation of transcription of the Dnmt1 gene by Sp1 and Sp3 zinc finger proteins doc
... E2F and
p53 also bind [10]. Thus, regulation by Sp1 and Sp3 of target
genes might be involved in the cell cycle. Furthermore, the
activity of p300 is dependent on gene dosage during early
embryogenesis. ... reagents
and valuable discussions. This work was supported by the Special
Coordination Funds of RIKEN, by grants from the Ministry of
Education, Science, Sports, Cu...
Báo cáo Y học: Regulation of a1,3galactosyltransferase expression in pig endothelial cells Implications for xenotransplantation doc
... the
Prime-a-gene labeling system (Promega). Double-positive
clones were purified by secondary and tertiary r ounds of
screening and genomic DNA inserts were purified using
poly(ethylene glycol) precipitation ... van den Berg
1
and David H. Joziasse
1
1
Department of Molecular Cell Biology, Research Institute of Immunology and Inflammatory Diseases and
2
Department of Medical...
Báo cáo Y học: Regulation of RAS in human platelets Evidence that activation of RAS is not sufficient to lead to ERK1-2 phosphorylation pot
... secondary
responses, aggregation mediated by t he integrin GPIIb-IIIa
was inhibited by EGTA and the activation m ediated by
thromboxane A
2
and ADP were blocked by indomethacin
and apyrase, respectively. ... study
down -regulation of the RAS–ERK signalling p athway and
other functions of RAS. Down -regulation of the RAS–
ERK pathway may be a critical step in the proces...
Báo cáo Y học: Regulation of stress-activated protein kinase signaling pathways by protein phosphatases pot
... phosphorylation of
conserved tyrosine and threonine residues within the
catalytic domain. This phosphorylation is mediated by dual
specificity protein kinases, members of the MAPK kinase
(MKK) family. ... pharmacological inhibition of protein phospha-
tase 1 by 1 ,2-dioleoyl- sn-glycero-3-phosphate (PA); the
activation of PP2A by high doses of PA, however, d ecreased
JNK act...
Báo cáo Y học: Regulation of glypican-1, syndecan-1 and syndecan-4 mRNAs expression by follicle-stimulating hormone, cAMP increase and calcium influx during rat Sertoli cell development pptx
... syndecan-1
and syndecan-4 mRNA expression in 30-days-old rat Sertoli
cells (Tables 2 and 3). Indeed, FSH increased syndecan-1
and syndecan-4 mRNAs expression by +40 and +53%,
respectively, and ... induced by activation of signaling processes. It was
shown that glypican-1 is downregulated by the presence of
both bFGF and TGF-b1 in fibroblasts [11] and by bFGF in
mature...
Báo cáo Y học: Regulation of peptide-chain elongation in mammalian cells pptx
... ADP-ribosylated by diphtheria toxin
[25]. ADP-ribosylation inhibits the activity of eEF2.
Phosphorylation of eEF2 inhibits its activity, in translo-
cation and in poly(U)-directed polyphenylalanine synthesis
[26,27], ... also
increase the phosphorylation of the valyl-tRNA synthetase
that associates with eEF1A/B. The available evidence
suggests that phosphorylation of eEF1A/B...
Báo cáo Y học: Regulation of mammalian translation factors by nutrients pot
... sites most profoundly
affected by rapamycin, may be regulated by nutrients
through the mTOR pathway.
REGULATION OF 4E-BP1 BY AMINO
ACIDS
In a number of kinds of mammalian cells, amino acids exert
marked ... intracellular pool of amino acids whose size is
determined by the rates of protein degradation and
synthesis, and by the availability of extracellular amino
aci...
Báo cáo y học: "κ Regulation of NFκB signalling during inflammation: the role of hydroxylases" potx
... under-
standing of the mechanism of hypoxia-induced NFκB activity.
The fact that the inhibitory action of hydroxylases is at the
level of the IKK complex through suppression of catalytic
activity means ... prolyl hydroxylase (PHD)-1 controlling
activity of NFκB. IKKβ expression and activity were found to
be increased by hypoxia [11]. Interestingly, IKKβ (and IKKα)
con...
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