Báo cáo y học: "Methionine aminopeptidase-2 blockade reduces chronic collagen-induced arthritis: potential role for angiogenesis inhibition" docx

... 13 (page number not for citation purposes) Vol 9 No 6 Research article Methionine aminopeptidase-2 blockade reduces chronic collagen-induced arthritis: potential role for angiogenesis inhibition John ... Diego, CA, USA). For CIA experiments, analy- sis of different treatments was carried out with a two-way anal- ysis of variance. Histology data were analysed by χ 2 t...

Ngày tải lên: 09/08/2014, 10:22

... Martel-Pelletier J: The new collagenase, collagenase-3, is expressed and synthesized by human chondrocytes but not by synoviocytes: A role in osteoarthritis. J Clin Invest 1996, 97:2011-2019. 38. Guévremont ... (PReboul). References 1. Loeser RF, Yammani RR, Carlson CS, Chen H, Cole A, Im HJ, Bur- sch LS, Yan SD: Articular chondrocytes express the receptor for advanced glycation end produ...

Ngày tải lên: 09/08/2014, 10:20

... valve dysfunct ion resulting from valve calcification. In all patients a chest radiography and coronary angiography was performed before reoperation. A 64 Multidetector Computed Tomography (MDCT) with ... chest radiography and coronary angio- graphy was performed before reoperation. A 64 Multidetector Computed Tomography (MDCT) with retrospective ECG gating study was performed in four patient...

Ngày tải lên: 10/08/2014, 09:22

... re- weighed 18 . The wet to dry weight ratio was calculated by dividing the wet by the dry weight. Myeloperoxidase assay Myeloperoxidase (MPO), a marker of pulmonary neutrophil accumulation ... artery for blood gas analysis with a blood-gas analyzer (GEM Premier 3000, Instrumentation Laboratory, USA). Histology The middle lobe of the right lung was excised for histopathology. Sam...

Ngày tải lên: 25/10/2012, 11:00

... expression before and during infliximab ther-apy as detected by immunohistochemistryHMGB1 synovial protein expression before and during infliximab ther- apy as detected by immunohistochemistry. Nuclear, ... RL, Fink MP: HMGB1 is secreted by immunostimu- lated enterocytes and contributes to cytomix-induced hyper- permeability of Caco-2 monolayers. Am J Physiol Cell Physiol 2006, 290:C990-999....

Ngày tải lên: 09/08/2014, 10:23

... R, Melief CJ: Syner- gism of cytotoxic T lymphocyte-associated antigen 4 block- ade and depletion of CD25(+) regulatory T cells in antitumor therapy reveals alternative pathways for suppression ... of autoreactive cytotoxic T lymphocyte responses. J Exp Med 2001, 194:823-32. 15. Phan GQ, Yang JC, Sherry RM, Hwu P, Topalian SL, Schwartzentruber D: Cancer regression and autoimmunity induced b...

Ngày tải lên: 11/08/2014, 10:23

... chemical synthesized [13, 14]. The most commonly used is known as T-1095 (3-(benzofuran-5-yl)-2',6'-dihydroxy-4'-methylpropio- phenone 2'-O-(6-O-methoxycarbonyl-β-D-glyco- pyranoside) ... they are not hydrolysed by β-glucosidases in the intestine and can be adminis- tered orally [27]. Therefore, the aim of the present study was to evaluate the inhibitory effect of so...

Ngày tải lên: 26/10/2012, 10:04

... (4-hydroxy- 3-methoxyphenyl-b-hydroxypropionyl-CoA) into vanillin [28]. An other well known example is trans-o-hydroxy- benzylidenepyruvate hydratase/aldolase [29,30] (also known as is 2¢-hydroxybenzalpyruvate ... enoyl-CoA hydratase/ aldolase [26]; (B2) trans-o-hydroxybenzylidenepyruvate hydratase/al- dolase [29]; (B3) trans-2-carboxybenzalpyruvate hydratase/aldolase [32]; (C) 6-hydroxy-2-ke...

Ngày tải lên: 21/02/2014, 01:21

... proinflammatory cytokine, tumour necrosis factor a, and with various psychosocial measures [15]. In the mammalian cytoplasm, HSP60 may play important roles including chaperone activity, immunophi- lin, ... cytoplasmic HSP60. These results suggest that HSP60 is not quickly imported into the mitochondria after being synthesized in the cytoplasm. Recently, it has been shown that cytoplasmic HSP60...

Ngày tải lên: 08/03/2014, 09:20

... shown to inhibit de-glycosylation of g lycopeptides or glycoproteins by N-glycosidase F [27], N-glycosidase A was used for de-glycosylation. The molecular mass of de-glycosylated DUP99B was determined ... glycosyl group reduces the critical concentration in a bioassay The biolo gical activity of t he peptide lacking the glycosyl group was d emonstrated by injecting synthetic DUP99B (sDUP9...

Ngày tải lên: 08/03/2014, 22:20