... otypic analysis (at the p rotein level), the f ew animals yielding in their milk the a s1 -CasM variant were exclusively heterozygous M/F a t the a s1 -Cas locus. There- fore, analysis o f their ... variant, given the intensity of the isoelectrofocusing bands and the surface of the relevant peak in RP-HPLC. Fig. 6. Nucleotide sequence of the expected a s1 -CasM cDNA...
Ngày tải lên: 22/02/2014, 04:20
... antero-posterior view) and at the right femoral neck, by dual-energy X ray absorptiometry using a QDR 4500 device (Hologic, Waltham, MA, USA). Quality control for the device was performed by daily assessment of ... Concomitant Therapy] protocol [7]). All of these patients were included in the study and followed over 1 year. RA activity was evaluated using the Disease Act...
Ngày tải lên: 09/08/2014, 10:20
Báo cáo y học: " A scalable, fully automated process for construction of sequence-ready barcoded libraries for 454" pps
... which the optical plate can sit and be defined on the deck of any automation. Settings used for plate-based shearing of DNA are: Duty Cycle of 5; Intensity of 5; Cycle per Burst of 500; Seconds of ... sequences are added to the end of the 454 A adapter via DNA synthesis (Integrated DNA Tech- nology). The lengths of each portion of the adapter and the appr...
Ngày tải lên: 09/08/2014, 20:21
Báo cáo y học: "A scalable, fully automated process for construction of sequence-ready human exome targeted capture libraries" pot
... development of critical quality control assays, both in terms of their sensitivity to the samples at the point at which they are assayed, as well as their utility as a predictor of sequen- cing quality. ... 4329001). Robot performance quality control by dye handling Precision performance of the liquid handling robot is maintained by regular quality control. A dummy run is perf...
Ngày tải lên: 09/08/2014, 22:23
Báo cáo y học: "A case-series study to explore the efficacy of foot orthoses in treating first metatarsophalangeal joint pain" pot
... agreement with other authors who have explored the efficacy of variously produced foot o rthoses for other indications [45,46]. Contrary to the hypothesised mode of action [16], the exploratory analysis ... Microsoft Excel™ and SPSS version 15 for Windows. The analysis strategy was divided into two phases, an efficacy phase and an explorato ry phase. For the efficacy a...
Ngày tải lên: 10/08/2014, 21:24
Tài liệu Báo cáo Y học: Interallelic complementation provides genetic evidence for the multimeric organization of the Phycomyces blakesleeanus phytoene dehydrogenase doc
... 2002 understanding of the function and organization of the enzyme complex, the analysis of mutant a lleles of the ge nes involved in the biosynthetic pathway c an certainly provide valuable information. In ... been described for both Zygomycetes. In Phycomyces they complement neither the carR nor the carA mutants, and i n Mucor they complement neither the carP no...
Ngày tải lên: 22/02/2014, 04:20
Báo cáo y học: "Cold hands — strained heart? Advances in the management of Raynaud’s phenomenon and pulmonary hypertension" ppt
... at 1 year and 2 years of 96% and 89% compared with Viewpoint Cold hands — strained heart? Advances in the management of Raynaud’s phenomenon and pulmonary hypertension Frances C Hall University of ... processes underlying RP and PAH contribute to the familiar pattern of skin, renal and gastrointestinal pathology. The emergence of effective and conveniently admini...
Ngày tải lên: 09/08/2014, 06:23
Báo cáo y học: "A cell-cycle independent role for p21 in regulating synovial fibroblast migration in rheumatoid arthritis" pps
... occurring in the presence of MMC, we deter- mined the number of WT and p21 (-/-) FLS in the presence and absence of MMC at the end of the assay and compared it with the number of cells plated at the ... phases of the cell cycle is dependent on the activities of cyclin dependent kinases (cdks) bound to their cognate cyclins [1,2]. Another level of cell...
Ngày tải lên: 09/08/2014, 08:22
Báo cáo y học: "Pro-apoptotic Bid is required for the resolution of the effector phase of inflammatory arthritis" pdf
... prevented by the overexpression of Bcl- 2/Bcl-x L or by the complete ablation of Bax and Bak [22]. The induction of apoptosis mediated by the extrinsic pathway is initiated by binding of death ligands ... macrophages. Figure 4 Loss of Bid does not alter the cytokine and chemokine milieu of the jointLoss of Bid does not alter the cytokine and chemokine milieu...
Ngày tải lên: 09/08/2014, 10:20
Báo cáo y học: "Adherence with urate-lowering therapies for the treatment of gout" pps
... is solely the responsibility of the authors and does not necessarily rep- resent the official views of the National Institute of Arthritis and Muscu- loskeletal and Skin Diseases or the National ... interpretation of the data, and critiquing of drafts of this article. BB was involved in the design of this project, analysis and interpreta- tion of the...
Ngày tải lên: 09/08/2014, 14:20