Báo cáo y học: "The proinflammatory cytokines IL-2, IL-15 and IL-21 modulate the repertoire of mature human natural killer cell receptors" pot

... in the repertoire of murine NK cells [18]. In the present study we assessed the effects of IL-2, IL-15 and IL-21 on the human NK cell repertoire, and our findings indicate that addition of IL-21 to ... proinflammatory cytokines IL-2, IL-15 and IL-21 modulate the repertoire of mature human natural killer cell receptors Casimir de R...

Ngày tải lên: 09/08/2014, 10:22

... other cytokines (e.g. IL-8, IL-6, and leukotriene inhibitory factor), proteases, and prostaglandin E 2 (PGE 2 ) [30]. Synthesis of the inflammatory cytokines IL-1 and TNF-α and expression of their ... by the proinflammatory cytokines IL-1 and TNF-α [29–31,36]. NO may be involved in cartilage catabolism by inhibiting the synthesis of colla- gen and PG, enhancing...

Ngày tải lên: 09/08/2014, 01:21

... malignancy and serious infection? Commentary on the meta-analysis by Bongartz et al. Arthritis Res Ther 2006, 8:111. Letter Response to commentary by Dixon and Silman on the systematic review and ... practice and biologically plausible, but they also fulfill the dose-effect criterion for causality. The low risk in the comparison group may be real, the result of chance, o...

Ngày tải lên: 09/08/2014, 08:22

... citation purposes) cytotoxicity was primarily determined by the color of media and cell viability by trypan blue exclusion. Cells were counted for the number of living cells every 24–48 hrs. Subsequent ... Due to the presence of highly acti- vated NF-κB pathway and tightly controlled cell cycle pro- gression the infected cells rely on these two mechanisms for its surviva...

Ngày tải lên: 10/08/2014, 05:21

... peels, in the category of crops and crop by-products and were accessed by both tethering and hand feeding and by scavenging. Maize grains are pri- marily from farmers’ own production and peels ... sources. The quantity and quality of these feeds were not the subject of this study, but emp irical literature shows a wide var- iation in the crude protein (CP) content o...

Ngày tải lên: 10/08/2014, 09:21

... networks. The method the- oretically ensures the derivation of the most consistent network structure with respect to all of the datasets, thereby not only significantly alleviating the problem of data ... measuring the strength of the relationship between gene expression and the response variable. It uses repeated permutations ofthedatatodetermineiftheexpressionofa...

Ngày tải lên: 11/08/2014, 03:20

... networks. The method the- oretically ensures the derivation of the most consistent network structure with respect to all of the datasets, thereby not only significantly alleviating the problem of data ... construction and analysis of frontal cortex of HIV encephalitis (HIVE) is very useful to identify novel markers and potential targets for prognosis and therapy. M...

Ngày tải lên: 11/08/2014, 06:22

... the activation of macrophages and natural killer cell antibody dependent cellular cytotoxicity whereas IgG1 has very limited activity. In the present study the determination of contribution of individual ... such a way so that there is synergistic effect of both the domains, activa- tion of specific T cell help and neutralization of wild type isolates. The st...

Ngày tải lên: 11/08/2014, 10:23

... We therefore hypothesized that some of these cytokines may also be responsible for the induction of SYN expression. To test this hypothesis, we first examined the effects of proinflammatory cytokines ... mice. Induction of SYN expression by IL-1β and TNF-α in mouse synovial fibroblasts The production of proinflammatory cytokines by synovial mac- rophages and fib...

Ngày tải lên: 09/08/2014, 08:23

... mucous glands, resulting in the recruitment of activated immune and inflammatory cells to the site of inflammatory lesion, thereby amplify- ing and sustaining the inflammatory condition [8]. The pro-inflammatory ... stated otherwise. Results Effect of POMx on cell viability and pro-inflammatory cytokines expression in activated KU812 cells We first examined the cytot...

Ngày tải lên: 11/08/2014, 08:22