... ideally effective, safe, and well tolerated.NSAIDs have provided the mainstay of pain therapy, particu-larly in the early stages of disease, but are often associatedwith clinically relevant adverse ... gastrointestinal adverse events, we included an overallmeasure of gastrointestinal tolerability as well as individualgastrointestinal adverse events of nausea, vomiting, abdominalpain, dyspepsia, ... any pharmaceutical company.Authors' contributionsRAM was involved with planning the study, data extraction,analysis, and preparing the manuscript; SD with data extrac-tion, analysis, and...