Báo cáo y học: "Cartilage markers and their association with cartilage loss on magnetic resonance imaging in knee osteoarthritis: the Boston Osteoarthritis Knee Study" doc

... Biomarkers Network), AR47785, and AG18393. The study sponsor was not involved in the study design; in the collection, analysis, and interpretation of data; in the writing of the report; or in ... for age in analyses. The BOKS study assessed the local structural changes in the knees only and in only one knee (not both). It may be that other studies that...

Ngày tải lên: 09/08/2014, 10:21

... Member of the Hong Kong Pharmacology Society, International Conference on Ulcer Research, and the Gastrointestinal Pharmacology Section of International Union of Pharmacology. He serves on the editorial ... incubated with peroxidase-labeled streptavidin for 30 min and stained with diaminobenzidine-H 2 O 2 for 10 min. Finally, the sections were counterstained with Mayer...

Ngày tải lên: 08/08/2014, 18:20

... [17,18,23]. The high degree of primary structural variability of bradykinins in amphibian skin secretions, their differing spectra of bioactivity and the lack of information on bradykinin receptor subtypes ... variants of bradykinins, especially phyllokinin (bradykinyl-IYsulfate) and C-termin- ally extended forms in Rana frogs [12–15], would imply that the preprobradykinin o...

Ngày tải lên: 21/02/2014, 15:20

... Lanka. 3 Section of Epidemiology, Institute of Psychiatry, Kings College London, London, UK. 4 Goldsmiths, University of London, London, UK. 5 Sydney Medical School, University of Sydney, Sydney, Australia. 6 Department ... leaving was mainly influenced by A and C factors, with a small con- tribution from unique environmental influences. Stan- dard of living was heavily environmentally in...

Ngày tải lên: 11/08/2014, 16:22

... 0.05. The null hypothesis is that there is no differ- ence in the proportions of positive and negative studies analysing a determined polymorphisms be- tween the studies examining it within 1-3 ... genetic association studies is increasing exponentially. Nonetheless, genetic association reports are prone to potential biases which may influence the reported outcome. Aim: We...

Ngày tải lên: 25/10/2012, 10:51

... covering let- ter asking them to pass this to any relatives that they wouldbehappyforustoinviteandwhotheyfeelmay be interested in taking part. Care Coordinators will be informed about the study in a ... presentations given by the research team. They will be asked to discuss the study with relatives they are working with and to refer any relatives inter- ested in taking part...

Ngày tải lên: 11/08/2014, 15:22

... cross-competition for binding of erythropoietin and thrombopoietin to c-mpl and the erythropoietin receptor. On the other hand, it has been suggested that erythropoietin and thrombopoietin can synergistically ... under- lying polycythemia vera, chronic myelogenous leukemia, chronic idiopathic myelofibrosis, myelodysplastic syn- drome and other reasons for reactive thrombocytosis...

Ngày tải lên: 11/08/2014, 23:21

... previous study using the rab- bit anular puncture model, the injection of osteogenic protein- 1 into the NP induced an increased proteoglycan content of both the AF and the NP and the recovery of disc-height ... Hoyland JA, Freemont AJ: Interleukin-1 receptor antagonist delivered directly and by gene therapy inhibits matrix degradation in the intact degenerate human inte...

Ngày tải lên: 09/08/2014, 14:22

... lateral, and skyline views), and if on any of these views they had a definite osteophyte in the sympto- matic knee, then they were eligible for inclusion in the study. In addition, if they screened ... LaValley M, Bauer DC, Nevitt M, DeGroot J, Poole R, Eyre D, Guermazi A, Gale D, Felson DT: Cartilage markers and their association with cartilage loss on mag...

Ngày tải lên: 09/08/2014, 13:21

... fresh medium containing the same concentration of the glycosylation inhibitor w as added. Three days later, the conditioned medium was harvested and inspected by Western blotting for the presence ... were not detected in our recombinant glyco- protein. We demonstrate that t yrosine s ulfation and N-gly- cans individually affect heparin binding of the inhibitor. These findings m...

Ngày tải lên: 08/03/2014, 22:20