Báo cáo y học: "Correction: The PTPN22 1858C/T polymorphism is associated with anti-cyclic citrullinated peptide antibody-positive early rheumatoid arthritis in northern Sweden" pps

Báo cáo y học: " Presence and utility of IgA-class antibodies to cyclic citrullinated peptides in early rheumatoid arthritis: the Swedish TIRA project" docx

Báo cáo y học: " Presence and utility of IgA-class antibodies to cyclic citrullinated peptides in early rheumatoid arthritis: the Swedish TIRA project" docx

... implications. Introduction Rheumatoid arthritis (RA) is a chronic disabling inflammatory disease with increased risk of premature death, mainly due to coronary vascular disease [1], but modern therapeutic strate- gies in early ... 21:885-906. 2. Askling J, Dixon W: The safety of anti-tumour necrosis factor therapy in rheumatoid arthritis. Curr Opin Rheumatol 2008, 20:138-14...

Ngày tải lên: 09/08/2014, 10:23

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Báo cáo y học: "Relaxin''''s induction of metalloproteinases is associated with the loss of collagen and glycosaminoglycans in synovial joint" ppsx

Báo cáo y học: "Relaxin''''s induction of metalloproteinases is associated with the loss of collagen and glycosaminoglycans in synovial joint" ppsx

... sites, including the pubic symphysis and synovial joints. These findings also suggest that in fibrocartilaginous tissues, including the TMJ disc and possibly the pubic symphysis, relaxin decreases collagen ... and assessed the contribution of these proteinases to the changes in collagen and glycosaminoglycan (GAG) con- tent in fibrocartilaginous disc explants. Our findings are...

Ngày tải lên: 09/08/2014, 06:22

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Báo cáo y học: " High sensitivity C-reactive protein is associated with lower tibial cartilage volume but not lower patella cartilage volume in healthy women at mid-life" pdf

Báo cáo y học: " High sensitivity C-reactive protein is associated with lower tibial cartilage volume but not lower patella cartilage volume in healthy women at mid-life" pdf

... three-dimensional rendering. The volume of the particular cartilage plate was determined by summing the pertinent voxels within the result- ant binary volume. A trained researcher read each MRI. The intra-observer ... suggesting that subclinical inflammation may predispose to knee cartilage loss in the tibial compartment. This should be further assessed by a longitudinal study....

Ngày tải lên: 09/08/2014, 10:23

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Báo cáo y học: "High nuclear expression of STAT3 is associated with unfavorable prognosis in diffuse large B-cell lymphoma" doc

Báo cáo y học: "High nuclear expression of STAT3 is associated with unfavorable prognosis in diffuse large B-cell lymphoma" doc

... Hypermethylation silencing of SOCS (the Suppressor of Cytokine Signal- ing) genes leads to reactivation of STAT pathway, resulting in the resistance to ABT-869, a pr omising multi-targeted tyrosine kinase inhibitor [12]. ... zj@bjcancer.org 1 Department of Lymphoma, Peking University School of Oncology, Beijing Cancer Hospital & Institute; Key Laboratory of Carcinogenesis and Transla...

Ngày tải lên: 10/08/2014, 21:23

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Báo cáo y học: "Improving the delivery of care for patients with diabetes through understanding optimised team work and organisation in primary care" ppt

Báo cáo y học: "Improving the delivery of care for patients with diabetes through understanding optimised team work and organisation in primary care" ppt

... of the respondents. In addition to the main study analysis, the patient survey will be reported in its own right, including a comparison with the healthcare commission data (available from their website), ... measured, and their ability to predict quality of care over the subsequent 12 months is explored in the analysis. Participants and setting The study will be based...

Ngày tải lên: 11/08/2014, 05:21

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Báo cáo khoa học: N-Methylation in polylegionaminic acid is associated with the phase-variable epitope of Legionella pneumophila serogroup 1 lipopolysaccharide pptx

Báo cáo khoa học: N-Methylation in polylegionaminic acid is associated with the phase-variable epitope of Legionella pneumophila serogroup 1 lipopolysaccharide pptx

... Z would be s terically hindered b y interaction of one of the N-methyl groups at N 1 (that in cis orientation to N 2 )with the pyranose ring of legionaminic acid. The N-methyl signal in 3 gave strong ... bacterial polysaccharides in the wild-type strain, namely N-methylation of the 5-ace- timidoylamino group on a single legionaminic acid residue that is located, most lik...

Ngày tải lên: 08/03/2014, 10:20

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Báo cáo y học: "No evidence of major effects in several Toll-like receptor gene polymorphisms in rheumatoid arthritis" pdf

Báo cáo y học: "No evidence of major effects in several Toll-like receptor gene polymorphisms in rheumatoid arthritis" pdf

... and rheumatoid nodules), since these allow a definitive diagnosis early in the course of the disease. Our working hypothesis that TLR genes might be associated with greater disease severity by increasing ... to induce a T-helper type 1 isotypic switch in B lymphocytes, which may be involved in the pathogenesis of RA. Further evi- dence of the role for TLR9 comes from th...

Ngày tải lên: 09/08/2014, 01:22

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