Báo cáo khoa học: " The median non-prostate cancer survival is more than 10 years for men up to age 80 years who are selected and receive curative radiation treatment for prostate cancer" ppt

... survival is greater than 10 years for men aged up to 80 years at startof radiation treatment. The non -prostate cancer survival of men selected for radiation treatment is consistentlylonger than the ... median non -prostate cancer survival is more than 10 years for men up to age 80 years who are selected and receive curative radiation treatment for prostate cancer Paul A Blood*1 and Tom Pickles2Address: ... of radiation treatment. Median survival was found to be greater than 10 years in men aged up to 80 years at the start of their radiation treatment. This finding suggeststhat radiation oncologists...

báo cáo khoa học: " The health disparities cancer collaborative: a case study of practice registry measurement in a quality improvement collaborative" pot

... information from bill-ing data queried for age- appropriate groups to handentry.In 2000, HRSA supported the development and deploy-ment of electronic registry software. Over the next five years, ... ≥42 years) 16 100 .0%Women with pap test within last three years (age ≥21) 16 100 .0%Adults appropriately screened for colorectal cancer (age ≥51) 16 100 .0%Breast cancer follow -up and treatment Women ... access to the medical record datanecessary to report information related to diagnostic fol-low -up and treatment. There was no uniform workflow for data from institutions outside the HDCC, and...

Tài liệu Báo cáo khoa học: The splicing factor ASF/SF2 is associated with TIA-1-related/ TIA-1-containing ribonucleoproteic complexes and contributes to post-transcriptional repression of gene expression doc

... in the UTRs of the transcript and the trans-acting factors(RNA-binding proteins and noncoding regulatoryRNAs) that bind to these sequences. Among the beststudied regulatory sequences, the ... Interest-ingly, this phosphomimetic mutant was relocalized to the cytoplasm to the same extent as the wild-type pro-tein upon cycloheximide ⁄ actinomycin D treatment, demonstrating the ability of this mutant ... bothRRMs, whereas the RS domain is dispensable. More- over, RRM1 but not RRM2 is necessary and sufﬁcient to promote this cytoplasmic redistribution. However,in the context of the wild-type ASF⁄...

Báo cáo khoa học: The SWI⁄SNF protein BAF60b is ubiquitinated through a signalling process involving Rac GTPase and the RING ﬁnger protein Unkempt doc

... inhibitor of the nuclear exportprotein exportin 1 (Fig. 6B). This observation is strongevidence that UNK-ﬂ has the ability to shuttle between the nucleus and the cytoplasm and can therefore ... localized to the nuclear compart-ment (Fig. 6A). Conversely, UNK-ﬂ was detectedmostly in the cytosol; however, it was found to accu-mulate in the nucleus upon treatment of the cells withleptomycin ... localized in the cytoplasmiccompartment, but has the ability to shuttle between the nucleus and the cytoplasm, suggesting that the Rac- and Unkempt-dependent process lead-ing to BAF60b ubiquitination...

Báo cáo khoa học: The Vps4 C-terminal helix is a critical determinant for assembly and ATPase activity and has elements conserved in other members of the meiotic clade of AAA ATPases pdf

... sheets 7 and 8, the AAAdomain helix and the C-terminal helix). However, the majority of these proteins are likely to be other meioticclade AAA ATPases and have the AAA domain helix and the C-terminal ... Blackwell Publishing are not responsible for the content or functionality of any supplementarymaterials supplied by the authors. Any queries (other than missing material) should be directed to the corre-sponding ... destined for the cell surface is mediated bya receptor, Vps10p, which continuously recyclesbetween the late Golgi and the MVB [38]. Transportof Vps10p from the MVB to the late Golgi is indepen-dent...

Báo cáo khoa học: The modulation of metal bio-availability as a therapeutic strategy for the treatment of Alzheimer’s disease pptx

... social cost. There is no cure for AD, and the development of effective therapeutic strategies is hampered by a paucity of information on the biolo-gical mechanisms underlying the disease. The severityof ... research is to identify the up- stream biological mechanisms that trigger the development of AD. Identifying these mechanisms willsubstantially facilitate the development of more effect-ive therapeutic ... and NFTs may ameliorate some of the consequences of AD and no doubt lessen the bur-den of the disease, the biological mechanisms thatcaused them to develop will remain unchecked. The fundamental...

Báo cáo khoa học: The mouse Muc5b mucin gene is transcriptionally regulated by thyroid transcription factor-1 (TTF-1) and GATA-6 transcription factors pdf

... MUC5B by these transcriptionfactors is, however, unknown, and the development ofmurine models of lung diseases is necessary to gain aninsight into, and to understand, the regulation of the murine ... factors seems to be more gen-eral, and may affect the expression of other mucingenes, such as MUC2, MUC3 and MUC4, as theirpromoters also contain cis-elements for these tran-scription factors [6,13,42,43]. ... candidate to be a target gene of GATAsfactors in the primitive gut [8]. TTF-1 and GATA-6 are required for the formation and differentiation ofdistal epithelium [20,44,45]. In normal adult tissue,MUC4...

Báo cáo khoa học: "The Best of Both Worlds – A Graph-based Completion Model for Transition-based Parsers" pot

... removes the top element of the inputbuffer and pushes that element onto the stack. The reduce transition pops the top word from the stack. The swap changes the order of the two top el-ements on the ... ele-ment of the input buffer and pushes it to the stack. The left-arcltransition adds an edge with label lfrom the ﬁrst word in the buffer to the word ontop of the stack, removes the top element ... Syntactic and 85 and the outermost pair for the grand-siblings. Weuse the ﬁrst two siblings of the dependent from the left side of the head for the tri-siblings and the ﬁrst two dependents of the...

Báo cáo khoa học: The lipid translocase, ABCA4: seeing is believing Naomi Laura Pollock and Richard Callaghan ppt

... cause of disc ageing and what signiﬁcance it hasin the visual cycle is unclear. The investment in creat-ing the unique lipid composition of the OS discs, and the existence of other visual disorders ... The ECDs are locatedwithin the disc lumen (L) and substrate (ATR) is hypothesized to travel (arrow A) from the lumen into the cytoplasm. ABCA1 (B) is located in the plasma membrane and oriented ... onanalysis of the amino acid sequence and biochemicaldata, predicts that the ECDs are located in the disclumen, while the NBDs reside in the OS cytoplasm(Fig. 3A). There is good evidence to support...

Báo cáo khoa học: The C-terminus of viral vascular endothelial growth factor-E partially blocks binding to VEGF receptor-1 docx

... recruitment and pro-inﬂammatorygene expression. VEGFR-2 is bound by VEGF-A,VEGF-C and VEGF-D and is the primary signalingreceptor of VEGF-induced endothelial cell mitogenesis,angiogenesis and ... inﬂuence the orientation of loop 3 and the width of the groove, thereby affecting its ability to bind the VEGFRs [8]. The orientation of the receptor-bind-ing face of BPSVV660VEGF may therefore ... one of the ORFVNZ2VEGF monomers are missing, as they weredisordered due to their intrinsic ﬂexibility. The residues of VEGF-Athat form the groove implicated in VEGFR-1 binding, and the resi-dues...

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