... Sakai T, Sakaue H, Nakamura T, Okada M, MatsukiY, Watanabe E, Hiramatsu R, Nakayama K, Nakay-ama KI & Kasuga M (2007) Skp2 controls adipocyteproliferation during the development of obesity. ... mass. In addition, the mutants were also resistant to obesityinduced by the A ygene. Of particular note is the factthat the deficient mice showed a rate of weight gainand amount of food intake ... storage of the excess energy in the form of intracellular triacylglycerol droplets in adipose cells,leading to an increased fat mass and ultimately result-ing in obesity.Adipocyte hyperplasia (increase...