Báo cáo y học: "Elevated extracellular matrix production and degradation upon bone morphogenetic protein-2 (BMP-2) stimulation point toward a role for BMP-2 in cartilage repair and remodeling" pps
... was elevated on day 3 in tibial cartilage and on days 3 and 7 in patellar cartilage, but no longer was by day 21. Increased NITEGE staining (indicating aggrecanase activity) was found on days 7 and ... production and degradation upon bone morphogenetic protein-2 (BMP-2) stimulation point toward a role for BMP-2 in cartilage repair and remodel...
Ngày tải lên: 09/08/2014, 10:21
... directly but instead acts as a cofactor for the clea vage and activation of PAR4 [27]. Thrombin has been shown t o cleave and a ctivate PAR1, PAR3 and PAR4, whereas trypsin cleaves and activates PAR2. ... these pathways has a modulatory r ather than a mandatory role to play in mediating the proliferative response. In contrast, a recent report has shown that tryptase...
Ngày tải lên: 24/03/2014, 03:21
... report Variations in brachial plexus and the relationship of median nerve with the axillary artery: a case report Suruchi Singhal*, Vani Vijay Rao and Roopa Ravindranath Address: Department of Anatomy, ... Anatomy, St John's Medical College, Bangalore – 560034, India Email: Suruchi Singhal* - suruchisinghal@yahoo.com; Vani Vijay Rao - vanivijay03@yahoo.co .in; Roopa Ravindranath...
Ngày tải lên: 10/08/2014, 10:20
Báo cáo y học: "Elevated matrix metalloproteinase-9 in patients with systemic sclerosi" doc
... tissue characterized by microvacular damage and excessive fibrosis in the skin and internal organs, including the heart, lungs, and gastrointestinal tract. One of the major hallmarks of the disease ... measured by gel zymography We used gel zymography to study sera of 20 SSc patients and 10 healthy controls, all selected unsystematically, to ascertain the serum gelatinase activity o...
Ngày tải lên: 09/08/2014, 06:22
Báo cáo y học: "Elevated plasma homocysteine is positively associated with age independent of C677T mutation of the methylenetetrahydrofolate reductase gene in selected Egyptian subjects"
... Mukawa H, Tomida T, Suzuki T, Kamiya H, Matsui H, Hayakawa T. Relation of a common methylenetetrahydrofolate reductase mutation and plasma homocysteine with intimal hyperplasia after coronary ... were transformed logarithmically to approximate normal distribution, and such data were analysed statistically. Statistical analysis of the data analysis was carried out using the ANOVA t...
Ngày tải lên: 03/11/2012, 09:49
Báo cáo khoa học: D1 – Extracellular Matrix Proteins docx
... isoenzyme ADA1 and iso- enzyme ADA2. ADA1 and ADA2 differ in kinetic and immuno- chemical properties and probably are coded by separate genetic locus. ADA2 is a minor component of ADA activity in ... Biologicas, Madrid, Spain, 3 Vacular Pathology, Departament of de Physiology and Pharmacology, University of Salamanca, Salamanca, Spain, 4 Vas- cular Biology, Department of Bioqu...
Ngày tải lên: 23/03/2014, 15:20
Báo cáo y học: "Elevated expression of caspase-3 inhibitors, survivin and xIAP correlates with low levels of apoptosis in active rheumatoid synovium" potx
... have a role in maintaining active RA. The increase of both xIAP and survivin in active RA synovial tissue may be even more signifi- cant because of the known synergy of survivin and xIAP form- ing ... sections and formalin-fixed paraffin-embedded tissue were prepared from the synovial biopsies. When available, an additional synovial biopsy was placed into RNAlater (Ambion, Foste...
Ngày tải lên: 09/08/2014, 01:22
Báo cáo y học: "IL-17 induces production of IL-6 and IL-8 in rheumatoid arthritis κ synovial fibroblasts via NF-κB- and PI3-kinase/Akt-dependent pathways" doc
... Hata K, Andoh A, Shimada M, Fujino S, Bamba S, Araki Y, Okuno T, Fujiyama Y, Bamba T: IL-17 stimulates inflammatory responses via NF- κκ B and MAP kinase pathway in human colonic myofibroblasts. ... revealed that both synovial fibroblasts and T cells participate in the perpetuation of joint inflammation as dynamic partners in a mutual activation feedback, via secretion of cytok...
Ngày tải lên: 09/08/2014, 01:23
Báo cáo y học: "Lack of autoantibody production associated with cytomegalovirus infection" pdf
... or chi-square analysis. Regression analysis was performed using Sigma Plot (version 1.02; Jandel Corporation, San Rafael, CA, USA). Results Antibodies against Sm and RNP Using the manufacturer’s sera ... myosin: a model for the study of molecular mimicry in the pathogenesis of viral myocarditis. Immunology 1992, 75:513-519. 7. Toyoda M, Galfayan K, Galera OA, Petrosian A, Czer LS, Jo...
Ngày tải lên: 09/08/2014, 06:22
Báo cáo y học: "Tumor necrosis factor alpha and epidermal growth factor act additively to inhibit matrix gene expression by chondrocyte" pptx
... for some inflammatory mediators. Cell survival is essential for ensuring ongoing homeostatic maintenance of cartilage and for bringing about repair to damaged cartilage. Maintaining integrity of ... aggrecan and type II collagen mRNA by TNF-α and EGF individually, addi- tional signals beyond the MAPK pathway are probably involved when the factors are combined. The intracellul...
Ngày tải lên: 09/08/2014, 06:22