Báo cáo y học: "A case-control study of rheumatoid arthritis identifies an associated single nucleotide polymorphism in the NCF4 gene, supporting a role for the NADPH-oxidase complex in autoimmunity" doc

... frequencies of the SNPs are affected by the LD of the region, and the strati- fied analyses are based on the same SNPs and samples as the initial analysis and can therefore not be considered to be inde- pendent ... units in the study area and almost all of the (very few) private units participated in the study. The present study includes data from 1,842 RA p...

Ngày tải lên: 09/08/2014, 10:21

... contributions All authors read and approved the final manuscript. YO carried out the study design, Data analysis and writing, NK, NS, SK and HS performed data collection. Competing interests The authors ... Shigematsu Abstract We herein present a 60 yea rs old woman with Takayasu arteritis and an extensive thoracic aortic aneurysm who initially underwent a total aortic arch repl...

Ngày tải lên: 10/08/2014, 09:22

... polyarthritis at the time of treatment initiation. The fourth monkey was in a preclinical phase of the disease, as shown by elevation in serum acute phase reactants and synovial inflammation by arthroscopy. ... CNS parenchyma. The majority of these T cells are in an activated state [31]. Adhesion molecules on the BBB, such as ICAM-1 and VCAM-1, play important roles a...

Ngày tải lên: 09/08/2014, 01:21

... significantly decreases both the binding affinity and the blue shift, probably due to an increased rigidity of the unsaturated phospholipid acyl chains in the cholesterol-containing vesicles. In spite ... investigated the fluorescence properties of the W48 and W56 residues, either in combi- nation in the WT-penetratin, or separately in the W48F- and the W56F-pen...

Ngày tải lên: 31/03/2014, 23:20

... femoral condyles of rabbits 48 h post-injection and analyzed for GAG synthesis as described in Materials and methods. The results are shown as percentage change (mean ± standard error of the mean) ... of the synovial lin- ing. To evaluate cartilage structure damage, the shaved carti- lage under synovial lining was sectioned for histological analysis and TUNEL staining. H...

Ngày tải lên: 09/08/2014, 07:20

... evaluation of RA activity, and acute- phase reactants. The SDAI and CDAI also include the physician’s assessment of RA activity, and do not require transformation or weighting of the individual ... pooled indices for the assessment of rheumatoid arthritis disease activity are available to rheumatologists. Face and criterion validity of these instruments can be assessed...

Ngày tải lên: 09/08/2014, 07:20

... transcripts and 18 S rRNA probes were quantified by STORM and analysed separately. Data analysis revealed an important individual variation in both pen- 3a transcripts and 18 S rRNA signals with a decrease ... population involved in a phenomenon of lysis with a massive and early release of penaeidins; and (b) another population involved in phagocytosis of bacteria taking p...

Ngày tải lên: 18/03/2014, 01:20

... HLA-B27 Sanna Vähämiko, Markus A Penttinen and Kaisa Granfors Department of Bacterial and Inflammatory Diseases, National Public Health Institute, Turku, Finland Corresponding author: Kaisa Granfors, ... explanation of the association of HLA-B27 and SpA. Reactive arthritis (ReA) is an acute inflammatory joint disease belonging to the group of SpA. The term ReA was original...

Ngày tải lên: 09/08/2014, 06:23

... [68]. In many diseases strongly associated with EBV, such as nasopharyngeal carcinoma and Burkitt’s lymphoma, anti-EBV serologies are abnormal many years before the onset of disease. In nasopharyngeal carcinoma, ... Goodman M, Lanier AP, Huang AT, Hyams VJ, et al.: Application of Epstein-Barr virus serology to the diagnosis and staging of North American patients with nasophary...

Ngày tải lên: 09/08/2014, 07:20

... the assumption the relay phases stay constant not only for a single channel use, but for τ channel uses. Thus, they remain unchanged for the time it takes all relays to transmit their training ... channel estimates, the notion of “block phase noise” is introduced: the LO phases of the relays stay constant for a single channel use and change randomly afterwards...

Ngày tải lên: 21/06/2014, 17:20