Báo cáo y học: "IL-23 induces human osteoclastogenesis via IL-17 in vitro, and anti-IL-23 antibody attenuates collagen-induced arthritis in rats" ppt
Báo cáo y học: " A promoter haplotype of the interleukin-18 gene is associated with juvenile idiopathic arthritis in the Japanese population" pps
... chronic arthritis of child- hood and belongs to a group of clinically heterogeneous dis- orders including oligoarthritis, polyarthritis, systemic arthritis, secondary arthritis, and other arthritis ... func- tions. Interestingly, IL-18 is a unique cytokine that stimulates both T helper (Th)1- and Th2-type immune responses, depending on its cytokine milieu [3]. In combination wi...
Ngày tải lên: 09/08/2014, 07:20
Báo cáo y học: "The relationship between the rate of melatonin excretion and sleep consolidation for locomotive engineers in natural sleep setting" pptx
... periods in a sleep diary and collected urine samples during each day's main sleep period. The samples were subsequently assayed for the metabolite of melatonin in urine, 6- sulphatoxymelatonin ... self-rating of sleep quality on a scale of 1 (very poor) to 5 (very good). Production of melatonin during each day's main sleep period was inferred from urinary 6-sulphatoxymelatonin...
Ngày tải lên: 10/08/2014, 09:20
Báo cáo y học: "Expression of Human Globular Adiponectin-Glucagon-Like Peptide-1 Analog Fusion Protein and Its Assay of Glucose-Lowering Effect In Vivo"
... fusion protein exhibited significant glucose-lowering effect in diabetic mice and may be a promising agent that can treat type 2 daibetes by improving both insulin resistance and insulin secretion ... present in inclusion body. In order to recover its function, the fusion protein in inclusion body was refolded in urea gradient refolding buffer. And then, the refolded pro...
Ngày tải lên: 25/10/2012, 11:10
Báo cáo y học: "Characterization of Human Erythrocytes as Potential Carrier for Pravastatin: An In Vitro Study"
... pravastatin loaded erythrocytes Hematological Indices To determine the effect of loading process on erythrocytes, normal erythrocytes, erythrocytes sus- pended in PBS, and pravastatin-loaded erythrocytes ... Watanabe M, Sekine S, Yanagida Y, Kobayashi S. Orange juice increased the bioavailability of pravastatin, 3-hydroxy-3-methylglutaryl CoA reductase inhibi- tor, in rats and h...
Ngày tải lên: 25/10/2012, 11:10
Tài liệu Báo cáo Y học: Convulxin induces platelet shape change through myosin light chain kinase and Rho kinase ppt
... doi:10.1046/j.1432-1033.2002.03305.x substratum in many cell types [9,29]. Protein kinase A, once activated, phosphorylates myosin light chain kinase (MLCK), thus inhibiting its activity and causing a decrease in MLC phosphorylation ... 5883 Convulxin induces platelet shape change through myosin light chain kinase and Rho kinase Silvia Riondino, Pier P. Gazzaniga and Fabio M. Pulc...
Ngày tải lên: 21/02/2014, 01:21
Báo cáo Y học: Cold induces stress-activated protein kinase-mediated response in the fission yeast Schizosaccharomyces pombe pot
... shock induced a quick and transient phosphorylation of Sty1p that became dephosphorylated within 60–90 min. This is likely due to the activity of threonine-phosphatases Ptc1p and Ptc3p and tyrosine-phosphatase ... level only after 60 min (Fig. 1). Pyp1p and Pyp2p phosphatases appear to play a key role in the dephosphorylation of the osmotic stress-activated Sty1p [20]. Interestingly...
Ngày tải lên: 08/03/2014, 09:20
Báo cáo Y học: Monitoring the structural consequences of Phe12 fi D-Phe and Leu15 fi Aib substitution in human/rat corticotropin releasing hormone Implications for design of CRH antagonists pdf
... family of 40 structures and Table 1 contains a summary of statistical data indica- ting the quality of the 40 models and the average energy- minimized structure. The polypeptide chain of the human/ rat ... corticotropin- releasing factor receptors in anterior and intermediate lobes of pituitary and in brain following adrenalectomy in rats. Neurosci. Lett. 56, 121–128. 5. Perrin...
Ngày tải lên: 17/03/2014, 10:20
Báo cáo Y học: Structure of human immunodeficiency virus type 1 Vpr(34–51) peptide in micelle containing aqueous solution pptx
... IBI-2, Germany Human immunodeficiency virus type 1 protein R (HIV-1 Vpr) promotes nuclear entry of viral nucleic acids in nondividing cells, causes G 2 cell cycle arrest and is involved in cellular ... of Vpr plays an important role in Vpr oligomerization, contributes to cell cycle arrest activity, and is essential for virion incorporation and binding to HHR23A, a protein involve...
Ngày tải lên: 24/03/2014, 04:21
Báo cáo Y học: Association of human tumor necrosis factor-related apoptosis inducing ligand with membrane upon acidification pdf
... factor-related apoptosis inducing ligand with membrane upon acidification Gyu Hyun Nam and Kwan Yong Choi National Research Laboratory of Protein Folding and Engineering, Division of Molecular and Life Sciences, ... leakage induced by intrinsic membrane interaction using purified TRAIL and liposome systems. Release rate of liposome-entrapped dye induced by TRAIL as well as membrane bind...
Ngày tải lên: 31/03/2014, 08:20
Báo cáo Y học: Conformationally constrained human calcitonin (hCt) analogues reveal a critical role of sequence 17–21 for the oligomerization state and bioactivity of hCt ppt
... N,N¢-diisopropylethylamine; DMS, dimethylsulfide; EDT, ethanedithiol; hCt, human calcitonin; MBHA, 4-methyl benzhydryl- amine resin; Mtt, 4-methyltrityl; Pip, 2-phenylisopropyl; OFm, fluoren-9-yl methylester; ... obtained receptor binding d ata showed that (a) the introduction of the Asp17,Lys21-lactam bridge in hCt resulted in a significant increase in human Ct receptor binding affinit...
Ngày tải lên: 31/03/2014, 21:21