... (Bregs),regulatory DCs and suppressive macrophages on the onehand, and pro-inflammatory effector lymphocytes and monocyte-derived cells on the other, is likely to dictate the choice between tolerance and ... is an autoimmune disordercharacterized by chronic systemic and synovial tissueinflammation that, if not therapeutically tackled, ultimatelyleads to bone and cartilage destruction. Like other ... 2001,2:671-672.74. Alvarado-Sanchez B, Hernandez-Castro B, Portales-Perez D,Baranda L, Layseca-Espinosa E, Abud-Mendoza C, Cubillas-Tejeda AC, Gonzalez-Amaro R: Regulatory T cells in patientswith systemic...