Báo cáo y học: " Antipolymer antibody in Italian fibromyalgic patients" docx

... divided by the total number of tender points.Figure 1 Antipolymer antibody levels in fibromyalgia patients and in control individualsAntipolymer antibody levels in fibromyalgia patients and in control ... biotin-con-jugated monoclonal antibody directed to cytokine is addedand binds to cytokine captured by the first antibody. Streptavi-din–horseradish peroxidase is added and binds to the biotin-conjugated ... thepresence of antipolymer antibody (APA) seropositivity in 285 Italian patients affected by primary fibromyalgia (FM) and toverify whether APA levels correlate with disease severity andwith cytokine...

Báo cáo y học: " From antibody insult to fibrosis in neonatal lupus – the heart of the matter" pps

... CHB/myocarditiswith varying degrees of pathology parallel the resultsobtained exploiting in vitro coculturing systems. Physiologicapoptosis may initiate an inflammatory process via antibody binding and ingestion ... tissue may be unique to heart blockacquired in utero following autoantibody-initiated inflam-mation. Other inflammatory stimuli, as in Lyme disease,induce transient block [26], arguing against ... Macrophages that have ingested apoptotic cells in vitroinhibit proinflammatory cytokine production throughautocrine/paracrine mechanisms involving TGF-ββ, PGE2 andPAF. J Clin Invest 1998, 101:890-898.22....

Báo cáo y học: "Antiphospholipid antibody profiles in lupus nephritis with glomerular microthrombosis: a prospective study of 124 cases" pot

... may influence the dynamic equilibriumbetween hemostasis and fibrinolysis by cross-reacting withsome hemostatic and fibrinolytic proteases (e.g., plasmin,thrombin, t-PA, protein C, protein ... indices of renal tissue injuryRenal tissue injury was evaluated using activity and chronicityindices as previously reported by Austin and colleagues [34].The activity index was the sum of the ... homologousenzymatic domains. Autoantibodies to these proteases,including thrombin, plasmin, tissue plasminogen activator (t-PA), prothrombin, protein C, protein S, annexin II (A2), annexinV, and...

Báo cáo y học: " Regional coordination in medical emergencies and major incidents; plan, execute and teach"

... planning, teaching and training responsibilitiesoffers possibilities for planning, teaching and training disaster medicine by giving immediate feed-back based on real incidents.BackgroundIntroductionTo ... be included in the riskassessment regarding possible major incidents in thisregion. The purpose of this study was to find whether thisinstitution has achieved its primary tasks by analyzing ... long-lasting missions have been a visit by NATOmilitary ships (15 days), storm with flooding (12 days),European Championship in track and field sports (10days) as well as a bus crash (10 days). Since...

Báo cáo y học: "Special considerations in the treatment of patients with bipolar disorder and medical co-morbidities"

... family history, ethnicity, increasing age, centralobesity, physical inactivity, low HDL/high triglycerides,fasting glucose of 110 mg/dL or greater, gestational diabe-tes, hypertension, and polycystic ... Angiotensin Converting Enzyme CYP = Cytochrome P450 + Not all agents are appropriate for monotherapy. Inclusion in this table does not necessarily imply efficacy. * Currently FDA approved for use in ... portacaval shunting, thereby decreasing first passmetabolism; decrease in quantities and affinity of plasmaproteins, thereby increasing free-drug levels; increase in volume of distribution in patients...

Báo cáo y học: "Two-year Outcome of Turkish Patients Treated with Zotarolimus Versus Paclitaxel Eluting Stents in an Unselected Population with Coronary Artery Disease in the Real World: A Prospective Non-randomized Registry in Southern Turk

... clinical end points, clinical trials comparing the safety and efficacy between these DES types and BMSs have yielded inconsistent results. In the ENDEAVOR I, II,II Continued Access Registry ... CABG: coronary artery binding graft; CK: creatine kinase; MACE: major ad-verse cardiac events; MI: myocardial infarction; PES: paclitaxel-eluting stent; ZES: zotarolimus-eluting stent; ST: ... undergoing their initial and final angiograms. The glycoprotein IIb/IIIa inhibitor (Tirofiban) was administered at the operator’s discretion. All patients maintained an-ti-platelet therapy following...

Báo cáo y học: "Technical Considerations in Decompressive Craniectomy in the Treatment of Traumatic Brain Injury"

... craniectomy in decreasing ICP and improving pr o g n o sis in patients wi th refractory in- tracranial hypertension after TBI.2-8 Presently, th e European Brain Injury Consortium and Brain Trauma ... Nerv Syst 2005;21:1014-1015. 48. Taylor A, Butt W, Rosenfeld J, et al. A randomized trial of very early decompressive craniectomy in children with traumatic brain injury and sustained intracranial ... brain injury: evaluation of effects at one year. Crit Care Med 2003;31:2535-2538. 46. Josan VA, Sogouros S. Early decompressive craniectomy may be effective in the treatment of refractory intracranial...

Báo cáo y học: "Pathogenic organisms in hip joint infections"

... a large number of different binding molecules. Espe-cially fibrinogen, extracellular matrix proteins and glycosaminoglycans, including fibronectin and laminin, are components of the blood ... Teicoplanin and Vancomycin are used. Ex-tending this repertoire with newer antibiotics, espe-cially Linezolid, Daptomycin and Tigecyclin were introduced for PJI therapy. A valid rating for ... 237Microbiologic procedures in joint infections A differentiation of arthritis is practicable by examination of typical laboratory medicine and mi-crobiology characteristics in joint fluid. In addition to...

Báo cáo y học: "Genetic polymorphisms in the nucleotide excision repair pathway and lung cancer risk: A meta-analysis"

... common polymorphisms in DNA repair genes are continuously being identified, and these polymorphisms may play a pivotal role in sporadic carcinogenesis. A growing body of literature, including observations ... important for maintaining DNA integrity and preventing carcinogenesis. Recent lung cancer studies have focused on identifying the effects of single nucleotide polymorphisms (SNPs) in candidate ... their inability to repair UV-induced DNA lesions. These clinical findings are associated with cellular defects, including hypersensitivity to killing and the mutagenic effects of UV and the inability...

Báo cáo y học: "Prion propagation in vitro: are we there yet"

... following lengthy incubation periods. However, synthetic prions were not able to transmit disease directly to wild type mice. To obtain infectivity in wild type mice, synthetic prions were Int. ... produc-ing infectious amyloid fibrils, infectivity remained the most controversial characteristic of the amyloid fibrils generated by this assay. Prusiner and colleagues in- duced amyloid fibrils ... propagation of infectivity.23 Cell-Lysate Conversion Assay Saborio et al. introduced a system termed the cell-lysate conversion assay.24 This method describes incubating lysate of Chinese hamster...

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