Báo cáo khoa học: " Neoadjuvant radiochemotherapy in the treatment of fixed and semi-fixed rectal tumors Analysis of results and prognostic factors" pptx

Báo cáo khoa học: " Neoadjuvant radiochemotherapy in the treatment of fixed and semi-fixed rectal tumors. Analysis of results and prognostic factors" pptx

... Johnson D: Post- treatment TNM staging is a prognostic indicator of survival and recurrence in tethered or fixed rectal carcinoma afterproperative chemotherapy and radiotherapy. Int J Radiat OncolBiol ... compromise the local con-trol. In the management of distal rectal cancer, sphincter-spar-ing surgery is nowadays the main subject of controversy.One of the most important controversies is whether the degree ... J, Grandjean JP, Partensky C,Souquet JC, Adeleine P, Gerard JP: Influence of the intervalbetween preoperative radiation therapy and surgery ondownstaging and on the rate of sphincter-sparing...

Báo cáo khoa học: "Helical tomotherapy in the treatment of pediatric malignancies: a preliminary report of feasibility and acute toxicitty" doc

... HT at the Tomotherapy Unit of the Grupo IMO in the context of multidisci plinary national and international treatment protocols. All the patients were treated with curativeintent, including those ... to the Tomotherapy treatment planning system (Tomotherapy Inc., Madison, WI) toperform inverse treatment planning. The planning goalwas to deliver the prescription dose to at least 95% of the ... comparingdiff erent conventional photon, electron and IMRT tech-niques in the treatment of intraocular retinoblastoma.IMRT plans achieved best sparing of the bony orbit. The mean volume of bony...

Báo cáo khoa học: " CyberKnife® radiosurgery in the treatment of complex skull base tumors: analysis of treatment planning parameters" potx

... by the treating neurosurgeon. The treatingneurosurgeon and radiation oncologist determined the minimal tumor margin dose of the target volume and the treatment isodose. This discussion was influenced ... physicist input the specific treatment criteria, limiting the maximum dose tostructures such as the optic chiasm and brainstem. The majority of the treatments were given in five fractions. In general, ... parameters and the tumor volume, simplelinear regressions on tumor volume for each of the threeindices were performed. The estimates of the slopes and their 95% confidence intervals were determined....

báo cáo khoa học: "Angiogenesis inhibitors in the treatment of prostate cancer" pdf

... multi-tyrosine kinase inhibitor with anti-PDGFR activity. It is used clinically in the setting of chronic myelogenous leukemia and GI stromal tumors, where inhibition of the bcr-abl and c-kit tyrosine ... tumstatin and canstatin. The balance of pro and anti-angiogenic factors is what ultimately determines the state of the angiogenic switch.VEGF-A remains the best under stood, and perhaps the most ... PSAdeclines of less than 50%. There were no objectiveresponses at day 70. The study was thus interpreted as anegative s tudy and highlights some of the difficulties in designing and interpreting the...

Báo cáo khoa học: "Intravenous colistin in the treatment of sepsis from multiresistant Gram-negative bacilli in critically ill patient" ppsx

... patients died within 48 hours of the initiation of colistin;these patients were not included in the analysis because theywere not considered true therapeutic failures. Data on the remaining 24 patients ... of patients, the concomitant use of β-lactams, and the absence of a control group in the study do not allow for aclear verdict on the clinical effectiveness of colistin. On the other hand, the ... colistin, intravenous colistin sulfomethate sodium (Col-istin; Norma, Athens, Greece) was initiated at the discretion of the attending physician. The dosage of colistin, adminis-tered intravenously,...

Tài liệu Báo cáo khoa học: Nuclear receptors in the mosquito Aedes aegypti Annotation, hormonal regulation and expression proﬁling ppt

... blocked. The presence of 20E,however, favors the formation of the AaEcR⁄ AaUSPheterodimer [13], indicating that the regulation of the activity of these proteins occurs through protein–pro-tein interactions, ... reorganization of the follicular epithelium in the resulting adults [40]. DmE75A and DmE75Bhave been implicated in deﬁning the transition stages8 and 9 of the egg chambers through either inducingor ... well as the sequences of the humanorthologs. When different isoforms were recovered,only the longest amino acid sequences that included the DNA binding, hinge and ligand-binding domainswere...

Tài liệu Báo cáo khoa học: Electrostatic contacts in the activator protein-1 coiled coil enhance stability predominantly by decreasing the unfolding rate docx

... synthesized for analysis, extending the number of interactions from 10to 45, permitting a rigid interpretation in distinguish-ing interacting from noninteracting proteins. OneFig. 1. Schematics of library ... ellipticity in the initial 5 ms of instrument deadtime.Again, the inset shows two-state and three-state ﬁts to the ﬁrst2 seconds of the transient, with the latter clearly providing the bet-ter ... displayed biphasic kinetics in the foldingdirection, indicating the existence of a folding interme-diate. In this study, it was ascertained that the ﬁrstreaction phase was fast and concentration...

Tài liệu Báo cáo khoa học: Final steps in the catabolism of nicotine Deamination versus demethylation of c-N-methylaminobutyrate doc

... expression of these genesdepends on the presence of nicotine in the growthmedium and we have determined the enzyme activities of the proteins. Our results demonstrate the presence of two pathways of ... pyridine ring and of c-N-methyl-aminobutyrate (CH3-4-aminobutyrate) from the pyrrolidine ring of the molecule. Surprisingly, two alternative pathways for the ﬁnal steps in the catabolism of ... pyrrolidine moiety of nicotine.Expression of the genes of these enzymes was dependent on the presence of nicotine in the growth medium. Thus, two enzymes of the nicotine regulon,c-N-methylaminobutyrate...

Tài liệu Báo cáo khoa học: Isochore structures in the chicken genome ppt

... the ﬁrst pointoccurring during the course of segmentation, and l and r denotethat the point occurs in the left and right subsequence, respect-ively. The integer denotes the times of segmentation. ... shown in Fig. 2, the domains obtained can delineate the variations of the cumulative GC proﬁle and the density distribution of CpG islands more and more accurately withdecreasing t0. On the other ... monotonously increasing (decreasing) linearfunction of n. To amplify the deviations of zn, the curve of zn$ n is ﬁtted by a straight line using the leastsquares technique,Isochores in the chicken...

Tài liệu Báo cáo khoa học: Oxidative stress in the hippocampus after pilocarpineinduced status epilepticus in Wistar rats doc

... investigate the develop-ment of neuropathology in SE [6]. Despite numerousstudies clearly indicating the importance of enzymeactivity in the epileptic phenomenon, the mechanismsby which these ... remained unaltered. These results show evi-dence of neuronal damage in the hippocampus due to a decrease in GSHconcentration and an increase in lipid peroxidation and nitrite content.GSH and ... 1307inefﬁciency of the electron-carrying components of the mitochondrial transport chain, monoamine degradation,xanthine oxidase reaction, and metabolism of arachidon-ic acid. However, the...

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