Báo cáo y học: "Glucosamine prevents in vitro collagen degra

Báo cáo y học: "Glucosamine prevents in vitro collagen degradation in chondrocytes by inhibiting advanced lipoxidation reactions and protein oxidation" pdf

... article Glucosamine prevents in vitro collagen degradation in chondrocytes by inhibiting advanced lipoxidation reactions and protein oxidation Moti L Tiku, Haritha Narla, Mohit Jain and Praveen Yalamanchili Department ... which collagen degradation induced by activated chondrocytes is mediated by lipid peroxidation reaction, glucosamine decreases colla...

Ngày tải lên : 09/08/2014, 10:20

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Báo cáo y học: "Apigenin, a non-mutagenic dietary flavonoid, suppresses lupus by inhibiting autoantigen presentation for expansion of autoreactive Th1 and Th17 cells" potx

... OH, Gavrilin MA, Wewers MD, Guttridge DC, Grotewold E, Doseff AI: Apigenin blocks lipopolysaccharide-induced lethality in vivo and proinflammatory cytokines expression by inactivating NF-kappaB ... phosphorylation. J Immunol 2007, 179:7121-7127. 36. Liang YC, Huang YT, Tsai SH, Lin-Shiau SY, Chen CF, Lin JK: Suppression of inducible cyclooxygenase and inducible nitric oxide synthase...

Ngày tải lên : 09/08/2014, 14:20

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Báo cáo y học: " Substantial deletion overlap among divergent Arabidopsis genomes revealed by intersection of short reads and tiling arrays" ppt

... spaced by typically 10 bp, but always less than 40 bp, and are characterized by hav- ing no short read coverage and a tile signal ratio below an arbitrary threshold. According to the analysis of ... 144 loci by dideoxy sequencing [12]. Mapping with three mis- matches allowed in the 5', 28 bp of each 35- to 36-bp read to account for sequencing errors using MAQ (Mapping and A...

Ngày tải lên : 09/08/2014, 20:21

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Báo cáo y học: "Substantial deletion overlap among divergent Arabidopsis genomes revealed by intersection of short reads and tiling arrays" pps

... spaced by typically 10 bp, but always less than 40 bp, and are characterized by hav- ing no short read coverage and a tile signal ratio below an arbitrary threshold. According to the analysis of ... 144 loci by dideoxy sequencing [12]. Mapping with three mis- matches allowed in the 5', 28 bp of each 35- to 36-bp read to account for sequencing errors using MAQ (Mapping and A...

Ngày tải lên : 09/08/2014, 20:21

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Báo cáo Y học: The presence of a helix breaker in the hydrophobic core of signal sequences of secretory proteins prevents recognition by the signal-recognition particle in Escherichia coli doc

... and the preprotein is translocated by an insertion–deinsertion cycle of SecA into the SecYEG translocon [8]. Energy for the translocation process is provided by ATP hydrolysis by SecA [8,9] and ... cycling at SecYEG is driven by distinct ATP binding and hydrolysis events and is regulated by SecD and SecF. Cell 83, 1171–1181. 9. Duong, F. & Wickner, W. (1997) The SecDFy...

Ngày tải lên : 08/03/2014, 09:20

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Báo cáo y học: "Glucosamine affects intracellular signalling through inhibition of mitogen-activated protein kinase phosphorylation in human chondrocytes" pps

... glucosamine was inef- fective in preventing phosphorylation of this kinase. JNK and p38 are involved in cellular stress; they are phosphorylated in response to proinflammatory cytokines, resulting in activation of ... classical markers of inflamma- tion and cartilage degradation in OA joints. It achieved this by affecting phosphorylation of JNK and p38 MAPKs and conse- q...

Ngày tải lên : 09/08/2014, 10:21

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Báo cáo y học: "Key regulatory molecules of cartilage destruction in rheumatoid arthritis: an in vitro study" docx

... metalloproteinases and suppressed extracellular matrix synthesis, induction of catabolic cytokines/chemokines and proinflammatory inducible enzymes, and activation of NF-κB signaling pathway. Thus, ... followed by a third washing step. Proteins were detected by enhanced chemiluminescence and the membranes were briefly exposed to X-ray films (Amersham, Munich, Germany) for 30 s, 1...

Ngày tải lên : 09/08/2014, 10:22

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Báo cáo y học: "Intervertebral disc cells as competent phagocytes in vitro: implications for cell death in disc degeneration" pptx

... (derived from murine macro- phages, kindly donated by Robin May, University of Birming- ham, UK) was maintained in DMEM/F-12 supplemented with 10% FBS. HeLa cells (donated by Mann Nguyen, Robert Jones ... within cell clusters). Introduction Cells are the vital machinery for synthesising and maintaining the functioning matrix in all tissues and the intervertebral disc within the sp...

Ngày tải lên : 09/08/2014, 10:23

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Báo cáo y học: "Antiretroviral therapy at a district hospital in Ethiopia prevents death and tuberculosis in a cohort of HIV patients." ppt

... anaemia and total lymphocyte count (TLC) in predicting mortality in both the pre-HAART and the HAART groups. Anaemia, history of prolonged fever, history of easy fatigability, history of tuberculosis, ... suggested strategies include: early introduction of HAART, isoniazid (INH) prophylaxis and immune boosting mechanisms [15]. In the resource-limited settings such as in south Et...

Ngày tải lên : 10/08/2014, 05:20

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Báo cáo y học: "Suppression of nitric oxide production from nasal fibroblasts by metabolized clarithromycin in vitro" potx

... that CAM administered orally and M-4 synthetized from CAM cause a decrease in iNOS expression in cytosol after inflammatory stimu- lation, inhibiting superoxide generation and resulting in prevention ... treatment of airway inflammatory diseases, since M-4 does not show any antimicrobial activity [17]. NO is primarily derived from a cationic amino acid, L-arginine, and oxygen b...

Ngày tải lên : 11/08/2014, 03:20

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