... primary and hospital care. The ultimate clinical utility of a biomarker is defined by the degree it improves clinical decision making and adds timely information beyond that of readily available information ... 14 distress syndrome within 30 days following inclusion. The secondary endpoint was overall survival within 30 days following study inclusion. Outcomes were assessed during hos...
Ngày tải lên: 25/10/2012, 10:02
... SDS/polyacrylamide gel and stained with Coomassie Blue. In vitro kinase assay In this study, mainly two types of in vitro kinase assay were performed. First, we examined whether MAPK phosphory- lates ... noteworthy that these B-type cyclins are strictly regulated in terms of protein amounts during cell cycling by transcription and ubiquitin-mediated proteolysis [11]. Second, t...
Ngày tải lên: 17/03/2014, 23:20
báo cáo hóa học: " Expression profiles for macrophage alternative activation genes in AD and in mouse models of AD" pptx
... cells in the vicinity of amyloid deposits in AD express mRNA and proteins for pro-inflammatory cytokines, leading to the hypothesis that microglia demonstrate classical (Th-1) immune activation in ... factors including the type of phagocytic ligands, the types of non- phagocytic adhesion interactions, the extracellular matrix and the cytokine environment [6,42]. Multiple, di...
Ngày tải lên: 19/06/2014, 22:20
Báo cáo y học: "The differential contribution of tumour necrosis factor to thermal and mechanical hyperalgesia during chronic inflammation" pps
... mechanism leading to the infiltration and the resulting functional role that DRG macrophages might play in hyperalgesic responses in models of inflammatory disease. Traditionally, macrophage infiltration into ... 3a), ris- ing to four times the initial level by 7 days after induction of inflammation. In contrast to TNFR1, TNFR2 mRNA was pre- dominantly increased in the ipsilater...
Ngày tải lên: 09/08/2014, 06:23
Báo cáo y học: "Intra-articular injection of recombinant TRAIL induces synovial apoptosis and reduces inflammation in a rabbit knee model of arthri" pdf
... corresponding to the microscopic findings in hematoxylin and eosin staining. In addition, leukocyte infiltration into the synovial fluid of the inflamed knee joints following rTRAIL treatment was reduced ... estimate the degree of TUNEL staining in synovial tissue sections. Investigators blindly reviewed primarily two areas: synovial lining and subsynovial regions. The extent...
Ngày tải lên: 09/08/2014, 07:20
Báo cáo y học: : A new classification of HLA-DRB1 alleles differentiates predisposing and protective alleles for autoantibody production in rheumatoid arthritis" pptx
... modifications of several proteins by deimination of arginine residues by peptidy- larginine deiminases [3,4]. The citrulline moiety is the true determinant in proteins recognized by antiperinuclear ... such as RA, in light of the amino acid alignment of a protein encoded by a candidate gene remains a challenging task. In fact, the interac- tions between HLA-DRB1 molecules and...
Ngày tải lên: 09/08/2014, 10:20
Báo cáo y học: "A prospective study of androgen levels, hormone-related genes and risk of rheumatoid arthritis" pptx
... can trigger inflammatory cytokines such as TNFα and IL-6, key cytokines responsible for the inflammatory response in RA [25]. Alternatively, androgens may influence RA risk indirectly through conversion ... participated in the study design and interpretation of the data. JB participated in the study design and interpretation of the data. IDV partici- pated in the study desig...
Ngày tải lên: 09/08/2014, 14:22
Báo cáo y học: " Chylothorax after surgery on congenital heart disease in newborns and infants – risk factors and efficacy of MCT-diet" pot
... the duration of drainage, the day of maximum loss of chy- lou s and the type and duration of treatment (fatty acid- free MCT-enriched diet, TPN, octreotide, recanalisation of thrombosed veins by lysis, ... may appear due to injury of the thoracic duct, due to venous or lymphatic cong estion, central vein thrombosis, or diffuse injury of mediastinal lymphatic tissue in asso...
Ngày tải lên: 10/08/2014, 09:23
Báo cáo y học: "The evolving story of medical emergency teams in quality improvement"
... distinct career pathway. Involving such physicians in medical emergency teams will likely facilitate the dual roles of these as a clinical outreach arm of the intensive care unit and in identifying problems ... the study consisted of only a 5-minute debriefing to fill out the standardized MET form on each patient and a weekly 1-hour Commentary The evolving story of medical eme...
Ngày tải lên: 25/10/2012, 10:06
Tài liệu Báo cáo Y học: Exploring the role of a glycine cluster in cold adaptation of an alkaline phosphatase pdf
... were residues Gly261 and Gly262. The replacement of Gly262 by Ala resulted in an inactive enzyme. Substitution of Gly261 by Ala resulted to an enzyme with lower stability and increased energy of activation. ... Bouriotis 1,2 1 Department of Biology, Division of Applied Biology and Biotechnology, University of Crete, Greece; 2 Institute of Molecular Biology and Biotechn...
Ngày tải lên: 22/02/2014, 04:20