Báo cáo y học: "Regulation of the JNK pathway by TGF-beta activated kinase 1 in rheumatoid arthritis synoviocytes" pps

Báo cáo y học: "Regulation of the JNK pathway by TGF-beta activated kinase 1 in rheumatoid arthritis synoviocytes" pps

Báo cáo y học: "Regulation of the JNK pathway by TGF-beta activated kinase 1 in rheumatoid arthritis synoviocytes" pps

... of c-Jun N-terminal kinase by MEKK-2 and mitogen-acti- vated protein kinase kinase kinases in rheumatoid arthritis. J Immunol 2004, 17 2 :16 12 -16 18. 21. Huang Q, Yang J, Lin Y, Walker C, Cheng J, ... and TAK1 are especially important activators of the JNK pathway in FLSs. In the present study, we examined the hierarchy of these pro- teins in IL -1 -media...
Ngày tải lên : 09/08/2014, 10:20
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Báo cáo y học: "Extension of the PNA world by functionalized PNA monomers eligible candidates for inverse Diels Alder Click Chemistyr"

Báo cáo y học: "Extension of the PNA world by functionalized PNA monomers eligible candidates for inverse Diels Alder Click Chemistyr"

... illustrated in scheme 1/ Figure 1. Synthesis of the PNA building block backbone In the next step, the synthesis of the PNA back- bone monomer using the fluorenylmethoxycarbonyl (Fmoc) protection ... described by Atherton and Sheppard.[40] Synthesis of the Fmoc-C2-glycine-tert-butyl ester The synthesis of the peptide nucleic acid back- bone requires the in...
Ngày tải lên : 26/10/2012, 08:57
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Báo cáo Y học: Characterization of the exopolysaccharide produced by Streptococcus thermophilus 8S containing an open chain nononic acid doc

Báo cáo Y học: Characterization of the exopolysaccharide produced by Streptococcus thermophilus 8S containing an open chain nononic acid doc

... ÔheptaÕsaccharide HexfiPentfiHexfiHexfiSugfianhydro-Hex-ol -1- d .In addition to the B n and Y n ions, a secondary fragment ion was observed at m/z 4 21 originating from the loss of anhydro-Hex-ol -1- d from the Y 2 ion (586 16 5). In the 1D 1 H NMR spectrum of the isolated ... conformation, are the main factors in uencing their physical properties [27], the presence...
Ngày tải lên : 08/03/2014, 09:20
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Báo cáo Y học: Regulation of mammalian translation factors by nutrients pot

Báo cáo Y học: Regulation of mammalian translation factors by nutrients pot

... a small inhibitory effect on the rate of protein synthesis [10 ]. In skeletal muscle, the activation of protein synthesis elicited by leucine is inhibited by rapamycin, but only partially [ 91] . This ... protein synthesis by amino acids [92]. In isolated rat heart cells (ventricular myocytes), protein synthesis is acutely activated by insulin [70] and this is blocked b...
Ngày tải lên : 23/03/2014, 21:20
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Báo cáo khoa học: Regulation of the muscle-specific AMP-activated protein kinase a2b2c3 complexes by AMP and implications of the mutations in the c3-subunit for the AMP dependence of the enzyme docx

Báo cáo khoa học: Regulation of the muscle-specific AMP-activated protein kinase a2b2c3 complexes by AMP and implications of the mutations in the c3-subunit for the AMP dependence of the enzyme docx

... activation or the A 0.5 values for AMP. Importantly, we did not detect any increase in phosphorylation of Thr172 of a2 by the upstream kinases in the presence of increasing con- centrations of AMP. ... varying AMP concentra- tions (Fig. 1D). In line with this, we did not detect any increase in the activity of the AMPK a2b2c3 com- plexes in the presence of A...
Ngày tải lên : 30/03/2014, 08:20
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Báo cáo y học: "Atrophy of the brachialis muscle after a displaced clavicle fracture in an Ironman triathlete: case report" docx

Báo cáo y học: "Atrophy of the brachialis muscle after a displaced clavicle fracture in an Ironman triathlete: case report" docx

... part of the musculocutaneous nerve explains the atrophy of the brachialis muscle the athlete observed. A hyposensitivity in the region of the deltoid muscle is the result of a lesion in the sensible ... He continued his training of indoor cycling and running and had no problems. Two weeks later b efore starting his swim training he continued to feel pain in his...
Ngày tải lên : 10/08/2014, 10:20
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Báo cáo y học: "Is there an association between anti-TNF monoclonal antibody therapy in rheumatoid arthritis and risk of malignancy and serious infection" ppt

Báo cáo y học: "Is there an association between anti-TNF monoclonal antibody therapy in rheumatoid arthritis and risk of malignancy and serious infection" ppt

... antibody trials. Summary of methods and findings The meta-analysis identified nine trials of the use of infliximab or adalimumab in RA. The authors did not include trials of etanercept because they ... within 6 weeks of starting therapy. Even excluding these cases, the increased risk compared with the comparison arms was still present, especially because there was only s...
Ngày tải lên : 09/08/2014, 08:22
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Tài liệu Báo cáo Y học: Regulation of transcription of the Dnmt1 gene by Sp1 and Sp3 zinc finger proteins doc

Tài liệu Báo cáo Y học: Regulation of transcription of the Dnmt1 gene by Sp1 and Sp3 zinc finger proteins doc

... play a critical role in progression of the cell cycle and the differentiation of cells [11 ,12 ]. The methylation of DNA plays a role in the regulation of gene expression [13 ,14 ], genomic imprinting ... Dnmt1 is enhanced during the S phase and then declines with the approach of the M phase. In a preliminary study, we found that levels of expression of Sp1 a...
Ngày tải lên : 22/02/2014, 07:20
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Báo cáo Y học: Elucidation of the role of fructose 2,6-bisphosphate in the regulation of glucose fluxes in mice usingin vivo 13 C NMR measurements of hepatic carbohydrate metabolism docx

Báo cáo Y học: Elucidation of the role of fructose 2,6-bisphosphate in the regulation of glucose fluxes in mice usingin vivo 13 C NMR measurements of hepatic carbohydrate metabolism docx

... follows: ½ 13 Glc6P 6  ½ 13 Glc6P 1  ¼ d½ 13 Glyc 6  dt d½ 13 Glyc 1  dt ffi ½D 13 Glyc 6  ½D 13 Glyc 1  % ½ 13 Glyc 6  ½ 13 Glyc 1  ð7Þ Eqn (7) implies that the initial rate of label incorporation into ... likely that the increased rate of 13 C label incorporation into the C6 position of glycogen in the ADM group is indicative of activated...
Ngày tải lên : 17/03/2014, 17:20
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Báo cáo y học: "κ Regulation of NFκB signalling during inflammation: the role of hydroxylases" potx

Báo cáo y học: "κ Regulation of NFκB signalling during inflammation: the role of hydroxylases" potx

... through studies involving the depletion of a component of the NFκB signalling pathway. Using mice lacking IKKβ (the key catalytic subunit in inflammatory signalling) in a variety of cell types, NFκB ... is at the level of the IKK complex. NFκB is also activated by ultraviolet light [14 ,15 ], by oxidative stress [16 ], by shear stress [17 ] and by other mechani...
Ngày tải lên : 09/08/2014, 01:22
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