Báo cáo y học: "The PTPN22 1858C/T polymorphism is associated with anti-cyclic citrullinated peptide antibody-positive early rheumatoid arthritis in northern Sweden" pdf
Báo cáo y học: "Estrogen receptor-α gene haplotype is associated with primary knee osteoarthritis in Korean population" docx
... primary knee OA, and genetic variations in the ER-α gene may be involved in OA. Keywords: estrogen receptor, haplotype, knee osteoarthritis, polymorphism Introduction Osteoarthritis (OA) is a ... association study in patients with primary knee OA (n = 151) and healthy individuals (n = 397) in the Korean population. Haplotyping analysis was used to determine the relationship betw...
Ngày tải lên: 09/08/2014, 01:23
Báo cáo y học: "Natural killer cell dysfunction is a distinguishing feature of systemic onset juvenile rheumatoid arthritis and macrophage activation syndrome" pot
... been reported in association with many rheumatic diseases, most commonly in systemic juvenile rheumatoid arthritis (sJRA). Clinically, MAS is similar to hemophagocytic lymphohistiocytosis (HLH), ... joints involved), polyarticular (five or more joints), and systemic. The systemic onset form, with its markedly febrile presentation, is certainly the most distinct clinical subtyp...
Ngày tải lên: 09/08/2014, 06:22
Báo cáo y học: "Mannose-binding lectin deficiency is associated with early onset of polyarticular juvenile rheumatoid arthritis: a cohort study" pdf
... article Mannose-binding lectin deficiency is associated with early onset of polyarticular juvenile rheumatoid arthritis: a cohort study Koert M Dolman 1,2 , Nannette Brouwer 2 , Florine NJ Frakking 1 , ... Jacobsen S: Genetically determined high serum levels of mannose-binding lectin and agalactosyl IgG are associated with ischemic heart disease in rheumatoid arthritis....
Ngày tải lên: 09/08/2014, 10:23
Báo cáo y học: "Interferon-induced protein IFIT4 is associated with systemic lupus erythematosus and promotes differentiation of monocytes into dendritic cell-like cells" pdf
... Erythematosus Disease Activity Index-2,000 (SLEDAI-2000) and analyzed usingy Spear- man's test. IFIT4, interferon-induced protein with tetratricopeptide repeats 4. Available online http:/ /arthritis- research.com/content/10/4/R91 Page ... Taylor M, Brahn E, Hahn BH, Tsao BP: Association of increased interferon-inducible gene expression with dis- ease activity and lupus nephritis in...
Ngày tải lên: 09/08/2014, 10:23
Báo cáo y học: "The PTPN22 1858C/T polymorphism is associated with anti-cyclic citrullinated peptide antibody-positive early rheumatoid arthritis in northern Sweden" pdf
... Rantapaa-Dahlqvist S: PTPN22 polymorphism and anti-cyclic citrullinated peptide antibodies in combination strongly predicts future onset of rheumatoid arthritis and has a specificity of 100% for the disease. ... stratified according to autoantibody Table 2 Frequency distribution of the 1858 C/T polymorphism of PTPN22 in patients with early rheumatoid arthritis an...
Ngày tải lên: 09/08/2014, 10:20
Tài liệu Báo cáo Y học: The Ikaros family protein Eos associates with C-terminal-binding protein corepressors pptx
... be involved in the interaction. In this way, it seems likely that proteins such as Eos may be able to bind to CtBP that is already associated with another PXDLS motif-containing protein. For instance, ... analysis of Ikaros has indicated that it contains distinct domains that are implicated in activating or repressing transcription [4,5,19,33]. One discrete domain within the N-ter...
Ngày tải lên: 21/02/2014, 01:21
Báo cáo Y học: The proximal cis-acting elements Sp1, Sp3 and E2F regulate mouse mer gene transcription in Sertoli cells potx
... determined by spectrophotometry at 260 nm, and its integrity was assessed by agarose gel electrophoresis. Polyadenylated RNA was prepared by oligo(dT) affinity chromatography using the PolyATract System ... Mer. Keywords:E2F;Mer gene; receptor tyrosine kinases; Sertoli cells; Sp1 and Sp3. Receptor tyrosine kinases (RTKs) are cell surface receptors that contain intrinsic protein tyrosine kinase...
Ngày tải lên: 08/03/2014, 23:20
Báo cáo Y học: The Emery–Dreifuss muscular dystrophy associated-protein emerin is phosphorylated on serine 49 by protein kinase A pptx
... phosphorylation at resi- due S49 is unlikely to directly regulate emerin-lamin A ⁄ C interaction in vivo. Protein kinase A-dependent phosphorylation of serine 49 Computer prediction analysis using ... Expressing emerin 1– 220 in our insect cell expression system resulted in very low yields with 50% of the protein insoluble, but mul- tiple bands were apparent from immunoblotting wit...
Ngày tải lên: 17/03/2014, 17:20
Báo cáo Y học: The solution structure of gomesin, an antimicrobial cysteine-rich peptide from the spider pptx
... of the hydrophobic-hydro philic balance in those highly cationic peptides is the key point for activity. This viewpoint has to be t aken with cau tion; in some cases, as with tachyplesins, the ... Brazil Gomesin is the first peptide isolated from s pider exhibiting antimicrobial activities. This highly cationic peptide is composed of 18 amino-acid residues including four cyst...
Ngày tải lên: 17/03/2014, 23:20
Báo cáo y học: "Weight loss, leukopenia and thrombocytopenia associated with sustained virologic response to Hepatitis C treatmen"
... level of leptin, insulin and cytokines but findings are not con- sistent (21-24). Alternatively, several studies showed that TNF levels were not increased during interferon therapy and postulated ... (57%) with the mean age of 52.5 years (Table 1). Fifty six percent were infected with genotype 1, 16% with genotype 2 and 28% with genotype 3. Clinical char- acteristics, relevant l...
Ngày tải lên: 26/10/2012, 09:39