Báo cáo y học: "Hypoxic conditions increase hypoxia-inducible transcription factor 2α and enhance chondrogenesis in stem cells from the infrapatellar fat pad of osteoarthritis patients" pps
Báo cáo y học: "Hypoxic conditions increase hypoxia-inducible transcription factor 2α and enhance chondrogenesis in stem cells from the infrapatellar fat pad of osteoarthritis patients" pps
... important role in regulat- ing the synthesis and assembly of matrix by IPFP-derived stem cells as they undergo chondrogenesis and that this has impor- tant implications for the use of the IPFP in cartilage ... 4-hydroxylase and pro- collagen lysyl-hydroxylase [45-47]. Through these actions, HIF1α affects the rate of synthesis of procollagen chains in vivo an...
Ngày tải lên: 09/08/2014, 10:20
Báo cáo y học: "Prevalence of Overactive Bladder, its Under-Diagnosis, and Risk Factors in a Male Urologic Veterans Population"
... Questions on LUTS included urinary frequency (2 questions), urgency (2), nocturia (1), incontinence (2) and emptying (1). The questionnaire also included medical and surgical history, demographic ... Our study found that 95% reported urinary frequency and 85% nocturia. The increase in our study is consistent with Irwin et al.’s epidemiologic study. Although a higher prev...
Ngày tải lên: 25/10/2012, 11:35
Báo cáo y học: "A k2A-positive Klebsiella pneumoniae causes liver and brain abscess in a Saint Kitt’s ma"
... ampicillin and intermediate to ampicillin/sulbactam. It was sensitive to the cephalosporins (cefazolin, cefotaxime, and cefepime), the fluoroquinolones (ciprofloxacin, levofloxacin), the aminoglycosides ... found in a man from Saint Kitts, a Caribbean island. Case Report A 49 year-old Afro-Caribbean man from the is- land of Saint Kitts presented to a Saint Kitts hosp...
Ngày tải lên: 26/10/2012, 09:53
Báo cáo Y học: Proteasome-driven turnover of tryptophan hydroxylase is triggered by phosphorylation in RBL2H3 cells, a serotonin producing mast cell line pptx
... ubiquitinylation of TPH protein was involved in the process, presumably by providing the targeting tag. In search for any connection between protein phosphorylation and TPH turnover, we examined the ... and 38 min in the presence and absence of okadaic acid, respectively (Fig. 1A, OA), suggesting an involvement of TPH phosphorylation in recognition of the enzym...
Ngày tải lên: 08/03/2014, 16:20
Báo cáo Y học: DAP kinase activity is critical for C2-ceramide-induced apoptosis in PC12 cells ppt
... phosphorylates the regulatory light chain of myosin II the phosphorylation sites being threonine 18 and serine 1 9 [22]. In this study, the synthetic peptide, skeletal myosin light chain kinase substrate ... (pro line 277 to leucine 323) containing the calmodulin-binding domain. In the K42A-DK mutant, a lysine residue at position 42 in t he kinase domain (asterisk) is repl...
Ngày tải lên: 24/03/2014, 00:21
Báo cáo y học: "IL-17 induces production of IL-6 and IL-8 in rheumatoid arthritis κ synovial fibroblasts via NF-κB- and PI3-kinase/Akt-dependent pathways" doc
... signaling in FLS from two patients with RA. Treating the cells with 20 µM LY294002, a chemical inhibitor of PI3-kinase, abolished the IL-17-induced increase in the production of IL-6 and IL-8 from ... are coincubated with antigen-stimulated T cells from RA patients [17], a likely hypothesis is that induction of IL-15 requires the combined influence of other p...
Ngày tải lên: 09/08/2014, 01:23
Báo cáo y học: "Decreased levels of soluble amyloid β-protein precursor and β-amyloid protein in cerebrospinal fluid of patients with systemic lupus erythematosus" ppsx
... from the central nervous system (CNS) frequently occur in patients with systemic lupus erythematosus (SLE). These symptoms are extremely diverse, including a state of dementia. The aim of this ... Yu CL: Cerebrospinal fluid interleukin-6, prostaglandin E2 and autoantibodies in patients with neuropsychiatric systemic lupus erythematosus and central nervous system infections....
Ngày tải lên: 09/08/2014, 01:23
Báo cáo y học: "Taurine chloramine differentially inhibits matrix metalloproteinase 1 and 13 synthesis in interleukin-1β stimulated fibroblast-like synoviocytes" doc
... immunostaining in both the cytoplasm and the nucleus. This may indicate that signalling pathways other than the MAPK and IκB pathways are involved in the stimulation of MMP-1 and MMP-13. In support of this ... subsiding to the basal levels of nonstimu- lated cells by 60 min. The activation of these pathways led to the activation of a number of transcrip...
Ngày tải lên: 09/08/2014, 10:20
Báo cáo y học: "Induction of HLA-B27 heavy chain homodimer formation after activation in dendritic cells" ppsx
... multiple bands in the 80 kDa region were visible (Figure 3a), and at 72 hours in KG-1.B27.H114D.D11 6Y cells, in which the higher of the bands detected in KG-1.B27 cells was only weakly vis- ible. The ... implying that these novel structures may not be displayed to the immune system at all times. Our data suggests that the behaviour of HLA-B27 on dendritic cells...
Ngày tải lên: 09/08/2014, 13:21
Báo cáo y học: " Elevated risks of death for diabetes mellitus and cardiovascular diseases in Italian AIDS cases" pps
... immunode- ficiency, given that these people are at risk of dying from a multitude of other causes. From a statistical viewpoint, the stratified analyses suffered from the small numbers of observed deaths in ... shown). DM and cardiovascular diseases were the underlying cause of death of 43 PWA (i.e., they cause 1.4% of all deaths): 14 deaths were caused by DM, 17 b...
Ngày tải lên: 10/08/2014, 05:21