Báo cáo y học: " Inhibition of indoleamine 2,3-dioxygenase-m

Báo cáo y học: " Inhibition of indoleamine 2,3-dioxygenase-mediated tryptophan catabolism accelerates collagen-induced arthritis in mice" doc

... 1 of 7 (page number not for citation purposes) Vol 9 No 3 Research article Inhibition of indoleamine 2,3-dioxygenase-mediated tryptophan catabolism accelerates collagen-induced arthritis in ... work is properly cited. Abstract Indoleamine 2,3-dioxygenase (IDO) is one of the initial and rate- limiting enzymes involved in the catabolism of the essential amino aci...

Ngày tải lên : 09/08/2014, 10:20

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Báo cáo y học: "Inhibition of antithrombin by hyaluronic acid may be involved in the pathogenesis of rheumatoid arthritis" potx

... pathogenesis of RA. The principal plasma inhibitor of thrombin is antithrombin, a single-chain 51 kDa glycoprotein that is synthesized in liver. The inhibitory activity of antithrombin on thrombin is ... heparin-binding region of antithrombin. However, such binding did not stimulate the activity of antithrombin as did heparin and heparan; in fact, it blocked the ability of ant...

Ngày tải lên : 09/08/2014, 06:22

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Báo cáo y học: "Effect of phospholipase A2 inhibitory peptide on inflammatory arthritis in a TNF transgenic mouse model: a time-course ultrastructural study" pptx

... role in the inflammatory response, inhibition of sPLA 2 is a target for the treatment of inflammatory diseases. Inhibition of sPLA 2 AA = arachidonic acid; ANOVA = analysis of variance; AS = arthritis ... RA by blocking the formation of proin- flammatory cytokines. A significant reduction of the inflammatory response has been reported in animals injected with natural...

Ngày tải lên : 09/08/2014, 01:23

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Tài liệu Báo cáo Y học: Inhibition of the MEK/ERK signaling pathway by the novel antimetastatic agent NAMI-A down regulates c-myc gene expression and endothelial cell proliferation ppt

... urokinase expression and Invasiveness by urinary trypsin inhibitor is mediated through inhibition of protein kinase C- and MEK/ERK/c-Jun – dependent signaling pathways. J. Biol. Chem. 276, 2015–2022. 6. ... inhibition of ERK1/2 phosphorylation may be lying upstream of ERK1/2. Using a serine/threonine kinase SPA assay kit, the capability of NAMI-A to affect the ERK1/2 phosphoryla-...

Ngày tải lên : 21/02/2014, 01:21

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Tài liệu Báo cáo Y học: Inhibition of nuclear pre-mRNA splicing by antibiotics in vitro pot

... splicing apparatus. The inhibitory effect of erythromycin and Cl-tetracycline were not allevi- ated by Mg 2+ (Fig. 3). Kinetic analyses using increasing concentrations of erythromycin, Cl-tetracycline ... was reduced by 60% in the presence of 500 l M Cl-tetracycline and by 95% in t he presence of 500 l M erythromycin and streptomycin (Fig. 2B,C). Tetracycline at 500 l M inhibited...

Ngày tải lên : 21/02/2014, 15:20

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Báo cáo Y học: Inhibition of hyaluronan synthesis in Streptococcus equi FM100 by 4-methylumbelliferone doc

... little involvement of MU-meta- bolites in the inhibition of HA synthesis by MU in FM100 cells. These above results indicate that something required for a fully functional HA synthesis system is ... (1983) Monensin inhibition of hyaluronate synthesis in rat ﬁbrosarcoma cells. J. Biol. Chem. 258, 7041–7046. 20. Smith, T.J. (1990) Retinoic acid inhibition of hyaluronate syn-...

Ngày tải lên : 08/03/2014, 09:20

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Báo cáo Y học: Inhibition of the SERCA Ca21 pumps by curcumin Curcumin putatively stabilizes the interaction between the nucleotide-binding and phosphorylation domains in the absence of ATP pot

... processes including: activation of apoptosis in Jurkat T-cells [5], inhibition of platelet aggregation [6,7] and inhibition of in ammatory cytokine production in macrophages [8]. Curcumin has also ... activity of a number of key enzymes such as cyclooxygenase [9], protein kinase C [10], protein tyrosine kinases [11] and a Ca 2þ -dependent endonuclease [12]. Many of these...

Ngày tải lên : 08/03/2014, 23:20

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Báo cáo Y học: Inhibition of glycosyl-phosphatidylinositol biosynthesis in Plasmodium falciparum by C-2 substituted mannose analogues pot

... transduction in macrophages by glycosylphosphatidylinositols of Plasmodium, Trypanosoma, and Leishmania: activation of protein tyrosine kinases and protein kinase C by inositolglycan and diacylglycerol moieties. ... organisms. In all systems investigated so far, mannosamine was able to inhibit GPtdIns biosynthesis. In T. brucei, mannosamine inhibits the incorporation of ethanolami...

Ngày tải lên : 31/03/2014, 23:20

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Báo cáo Y học: Inhibition of SERCA Ca2+ pumps by 2-aminoethoxydiphenyl borate (2-APB) 2-APB reduces both Ca2+ binding and phosphoryl transfer from ATP, by interfering with the pathway leading to the Ca2+-binding sites ppt

... FEBS 2002 Inhibition of SERCA Ca 2+ pumps by 2-aminoethoxydiphenyl borate (2-APB) 2-APB reduces both Ca 2+ binding and phosphoryl transfer from ATP, by interfering with the pathway leading to the ... Ca 2+ bindingbyboth reducing the rate constant for binding as well as increasing therateconstantforCa 2+ dissociation, could be explained by 2-APB binding to either one or both of these sit...

Ngày tải lên : 31/03/2014, 23:20

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Báo cáo y học: "Inhibition of macropinocytosis blocks antigen presentation of type II collagen in vitro and in vivo in HLA-DR1 transgenic mice" docx

... purposes) effect of amiloride and cytochalasin D was independent of NF- κB inhibition. Dose-response data obtained in the absence of inhibitors presented in Figures 5 and 6 were also analyzed by the four ... differential effect of the inhibition of uptake on presentation of the glycosylated and non-glycosylated CII 259–273 epitope was observed. In a previous report we...

Ngày tải lên : 09/08/2014, 08:22

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