Báo cáo y học: "Pro-apoptotic Bid is required for the resolution of the effector phase of inflammatory arthritis" pdf

... we profiled laminin chain expres- sion in cultured myocytes. Under serum-fed conditions, characterised by the presence of HASM cells of the prolif- erative/synthetic phenotype, the profile of laminin ... coating of laminin isoforms following 7-day serum deprivationFigure 4 Phase contrast images of ASM cells in the presence and absence of different coating of laminin is...

Ngày tải lên: 12/08/2014, 16:20

... [18]. Much of the existing knowledge of the importance of pro- tein methylation has been gained through the use of methylation inhibitors which result in the accumulation of proteins in their hypomethylated ... cytokine signaling [16]. The recent discovery of the enzyme family of the protein arginine methyltransferases (PRMTs), as well as technical advances that al...

Ngày tải lên: 13/08/2014, 09:20

... translocation is crucial for its function in the ␤-catenin pathway To determine whether nuclear localization of Dsh is required for its activity, we compared the abilities of DsNLSm and wild-type Dsh ... in embryo lysates at similar levels (Figure 5c). Thus, these find- ings indicate that the nuclear localization of Dsh is critical for its functional activity in th...

Ngày tải lên: 06/08/2014, 18:21

... Immunoblotting assay. LMC and WKC performed cell motility assay. JMH and FJT performed integrity of the data and the accuracy of the data analysis. CJL performed study concept and design, and wrote the manuscript. ... inhibitor (SP600125) for 48 h. Subsequently, we observed the ability of motil ity in LoVo cells by migration assay. Because DNA synth- esis was completely inhi...

Ngày tải lên: 10/08/2014, 10:20

... responsible for carrying out the experiments, for data analysis, and for drafted this manuscript; KYK was responsible for the analysis and design for the histologic study; OS oversaw the animal ... groups. For quantitat ive analysis of the airway mucous secretion, all histological slides of the left lung were randomly sorted and masked b efore observation. The qu...

Ngày tải lên: 12/08/2014, 13:22

... reflect distinct molecular scenarios (see Discussion). To exclude the influence of a potential compensatory functional redundancy of the two b-TrCP isoforms in cells in which only one of the isoforms ... oliver.keppler@med. uni-heidelberg.de 1 Department of Infectious Diseases, Virology, University of Heidelberg, Heidelberg, Germany Full list of author information is avail...

Ngày tải lên: 13/08/2014, 01:20

Ngày tải lên: 13/08/2014, 20:21

... elusive. The impact of AF on mortality is not clearly demonstrated in the ICU, with AF re ecting essentially the severity of the underlying disease. © 2010 BioMed Central Ltd Atrial  brillation is ... before the occurrence of AF, corroborating previous fi ndings on the hypothesis of an infl ammatory substrate in AF onset [2]. AF is the most signifi cant arrhythm...

Ngày tải lên: 13/08/2014, 21:20

... (Aptivus®, the latest entry to the PI class in 2005 quarter 3). (Neither of these drugs is featured individually but contributes to the category "Other PIs.") Similarly to the NRTIS, the later ... most of the rise can be explained by rising utilization, some is due to rising prices of both newer medications and those already established in the market. Medicai...

Ngày tải lên: 10/08/2014, 05:20

... USA. 15 Department of Medicine, University of California San Francisco, 50 Beale St, San Francisco, CA, 94105, USA. 16 Department of Epidemiology and Biostatistics, University of California San Francisco, ... individuals ≥50 years of age is rapidly increasing [4, 5], yet there is evidence that this older age group may not be as aware of HIV infection and the need for preve...

Ngày tải lên: 10/08/2014, 05:21