Báo cáo y học: "Falling into TRAPS – receptor misfolding in the TNF receptor 1-associated periodic fever syndrome" ppsx
Báo cáo y học: "Falling into TRAPS – receptor misfolding in the TNF receptor 1-associated periodic fever syndrome" ppsx
... having
TRAPS [11-13]. TNFR1 is the archetypal proinflammatory
receptor and a member of the TNF receptor superfamily – a
Review
Falling into TRAPS – receptor misfolding in the
TNF receptor 1-associated ... occur in the extracellular domain of TNFR1. In the
present review we discuss new findings describing aberrant
trafficking and function of TNFR1...
Báo cáo Y học: Probing intermolecular protein–protein interactions in the calcium-sensing receptor homodimer using bioluminescence resonance energy transfer (BRET) potx
... or AT1aD359-EYFP) the following day. The day
after transfection, the cells were split into poly
D
-lysine
coated 3.5 cm wells containing a glass slide (MatTek
Corp., Ashland, MA) in DMEM with ... is that the translation of
agonist binding to the ATDs of the family C GPCR
homodimer into G-protein coupling of the 7TM)7TM
moiety is mediated by another mechanism than that
prop...
Báo cáo y học: " Insights into endocrine-immunological disturbances in autoimmunity and their impact on treatment" doc
... [7].
Suppression of the hypothalamic–pituitary–adrenal axis,
however – especially in polymyalgia rheumatica, an inflam-
matory syndrome affecting older people – plays an important
pathogenetic role [8]. In fact, ... addition, mild exercise and training and a
decrease in the proinflammatory load – as obtained also by
the use of anticytokine therapy – can normalize s...
Báo cáo y học: "Transition into daylight saving time influences the fragmentation of the rest-activity cycle" potx
... the study and in the
drafting of the manuscript.
JL participated in the planning of the study and in the
drafting of the manuscript.
TP participated in the planning of the study, in the analy-
sis ... average by only 5 min 48
sec.
Some interesting findings emerged from subgroup analy-
sis. Here, our main finding was that transition into DST
enhanced the fragm...
Báo cáo y học: "nsights into female sperm storage from the spermathecal fluid proteome of the honeybee Apis mellifera" ppsx
... well-connected single
metabolic entity. It contains 5 of the 14 enzyme nodes present
in the seminal fluid, but also an extra 23 enzyme nodes that
combine the 6 clusters in the seminal fluid into a single ... concluded that the spermathecal glands are the main contributors to the
spermathecal fluid proteome. A detailed analysis of the spermathecal fluid proteins indicate...
Báo cáo y học: "An unusual case of gout in the wrist: the importance of monitoring medication dosage and interaction. A case report"
... a clinical syndrome caused by the deposition of
monosodium urate monohydrate crystals into synovial,
bursal, and cartilaginous tissue. The underlying metabolic
disorder is hyperuricemia. The ... in
any joint including the ankle, knee, hand, wrist, elbow,
sacroiliac joint and other joints of the spine, however
most commonly occurs in the lower extremity. In this
case, altho...
Tài liệu Báo cáo Y học: Soluble silk-like organic matrix in the nacreous layer of the bivalve Pinctada maxima A new insight in the biomineralization field pptx
... and
consequently the EDTA-IM. Hydroxyproline, hydroxy-
lysine and phosphoserine were not detected in WSM, WIM,
EDTA-SM and EDTA-IM.
The comparison of the amino acid composition of the
main peak obtained ... revealed the
predominance of two amino acids: alanine (39.2%) and
glycine (30%). Interestingly, the proportions are very similar
to those found in WSM for alanine and glyci...
Báo cáo y học: "Nature of Regulatory T Cells in the Context of Allergic Disease." ppsx
... activity by blocking of IgE binding. IL-10
reduces release of proinflammatory cytokines by mast cells.
The role of IL-10 in costimulatory pathways on B cells is
by blocking B7/CD28. Also, IL-10 inhibits ... 1993;92:64 4–5 1.
24. Durham SR, Ying S, Varney VA, et al. Grass pollen immunother-
apy inhibits allergen-induced infiltration of CD4+ T lymphocytes
and eosinophils in the nasal...
Báo cáo y học: "Efficacy and safety of aripiprazole in the treatment of bipolar disorder: a systematic review" pdf
... (dehydro-
genation, hydroxylation, and N-dealkylation), mainly by
cytochrome P450 2D6 (CYP2D6) and cytochrome P450
3A4 (CYP3A4) [60]. The parenteral drug is excreted only
in traces. There is only a minor effect ... (7-(4-[4-(2,3-dichlorophenyl)-1-piperazi-
nyl]butyloxy)-3,4-dihydro-2 (1H)-quinolinone (OPC-
14597), is a derivative of the dopamine autoreceptor ago-
nist 7-(3-[4-(2,3-dimet...
Báo cáo y học: " Chemokine blockade: a new era in the treatment of rheumatoid arthritis" ppsx
... by redundant
recruitment mechanisms is supported by the observation
that monocytes were still present within the inflammatory
infiltrates in the joints of the CCR2
–/ –
mice [19].
Data from the ... toward the synovial
compartment in RA [ 7–1 0].
Although these studies might suggest therapeutic
potential for chemokine and chemokine receptor blockade
in inhibiting chr...