Báo cáo y học: "CTLA4 polymorphism and primary Sjögren’s syndrome" doc

Ngày tải lên: 09/08/2014, 10:20

Ngày tải lên: 09/08/2014, 10:20

... the lymphoid protein tyrosine phosphatase (Lyp) has recently been found to be associated with several autoimmune disorders. The PTPN22 1858C/T polymorphism was origi- nally associated with type ... 1 Research article PTPN22 polymorphism and anti-cyclic citrullinated peptide antibodies in combination strongly predicts future onset of rheumatoid arthritis and has a specificity of 100%...

Ngày tải lên: 09/08/2014, 07:20

... population: a family-based study. Arthritis Res Ther 2007, 9:R63. 2. Friedlander M, Brooks PC, Shaffer RW, Kincaid CM, Varner JA, Cheresh DA: Definition of two angiogenic pathways by distinct alpha ... study [1] = 1.94, frequency of rs3738919-A allele in the controls = 0.078, significance level = 0.05). However, when the odds ratio is under 1.67, the power is limited to below 0.8, and this...

Ngày tải lên: 09/08/2014, 10:21

... epigenetic yield. Demethylating agents namely 5-azacytidine ( 5-aza-CR) and 5-aza-2’-deoxycytidine (5-Aza-CdR) are the only cytidine analogues that have been approved by the U.S. Food and Drug ... results from a RORa4-andRORg-dependent activation, which is rhythmically repressed by REV-ERBa and REV-ERBb. As p21 negatively regulates cell cycle progression by inhibiting the activity of CY...

Ngày tải lên: 10/08/2014, 09:20

... disease and vestibuloauditory symptoms. Systemic vasculitis is found in about 10% of cases. Case presentation: A 46-year-old female with Cogans’s syndrome and a history of arterial hypertension ... vascular matrix integrity and expression of the major matrix molecules was characterized by elastolysis and collagenolysis and thus a dramatic loss of structural integrity. Remarkably, ex...

Ngày tải lên: 10/08/2014, 09:22

... Minocycline treatment and pseudotumor cerebri syndrome. Am J Ophthalmol 1998, 126(1):116-121. 10. Friedman DI, Gordon LK, Egan RA, Jacobson DM, Pomeranz H, Harrison AR, Goldhammer Y: Doxycycline and ... patients may experience chronic disabling headache and visual disturbances. Early intervention is necessary to prevent permanent visual defects from ischemic optic neuropathy. The patho...

Ngày tải lên: 11/08/2014, 00:23

... proliferation Asthma Airway epithelium, Myofibroblasts, Airway smooth muscle Create an anti-inflammatory environment Inhibit airway wall remodeling Inhibit smooth muscle hypertrophy and hyperplasia Cystic fibrosis ... embryogenesis and generation of pluripotent embryonic cellsFigure 1 Cell lineage determination during embryogenesis and generation of pluripotent embryonic cells. The th...

Ngày tải lên: 12/08/2014, 18:21

... annum, and has high mortality. Current understanding of sepsis is predominately observational and correlational, with only a partial and incomplete understanding of the physiological dynamics ... circulation should play an essential role in disease origin and progression. For example, blood and lymphatic circulatory systems play important roles in the life of T-lymphocytes, as they...

Ngày tải lên: 13/08/2014, 23:20

... may help in revealing the pathophysiology of this probably underdiagnosed syndrome. Appendix • Diagnostic criteria for classical Sweet’ssyndrome (originally proposed by Su and Liu in 1986 and ... acute lymphoblastic leukemia, m yelodysplastic syndrome, Fanconi’s aplastic anaemia, congenital dyserythro- poietic anaemia, aseptic meningitis, Behchet’s disease, Takayasu arteriitis, systemic ....

Ngày tải lên: 11/08/2014, 03:21