... N-terminus of m5C-DNA methyltransferase Msp I is involved in its topoisomerase activity Sanjoy K. Bhattacharya* and Ashok K. Dubey† Department of Biochemical Engineering and Biotechnology, Indian Institute ... Equally intriguing is the fact that topoisomer- ase activity is associated with the methylase/endonuclease with a 5Â-CG-3Â in the recognition seq...
Ngày tải lên: 24/03/2014, 00:21
... citation purposes) Annals of General Psychiatry Open Access Primary research The relationship between antipsychotic medication adherence and patient outcomes among individuals diagnosed with bipolar ... pre- scribed medication and hospitalization. An analysis of factors leading to hospitalization among elderly patients with bipolar mania found lack of adhe...
Ngày tải lên: 08/08/2014, 23:21
Báo cáo y học: "The Inventory of Personality Organisation: its psychometric properties among student and clinical populations in Japan" pptx
... of 21 (page number not for citation purposes) Annals of General Psychiatry Open Access Primary research The Inventory of Personality Organisation: its psychometric properties among student and ... Japanese, in Japanese non-clini- cal (undergraduate student) and clinical populations. We examined the factor structure of the inventory by both exploratory and...
Ngày tải lên: 08/08/2014, 23:21
Báo cáo y học: "The angiogenesis inhibitor protease-activated kringles 1–5 reduces the severity of murine collagen-induced arthritis" ppsx
... Research and Therapy Vol 5 No 1 Sumariwalla et al. Research article The angiogenesis inhibitor protease-activated kringles 1–5 reduces the severity of murine collagen-induced arthritis Percy F Sumariwalla 1 , ... increased cellularity of the synovial lining of joints, before invasion by the synovium of the underlying cartilage and bone. This increased tissu...
Ngày tải lên: 09/08/2014, 01:21
Báo cáo y học: "Gene expression induced by interleukin-17 in fibroblast-like synoviocytes of patients with rheumatoid arthritis: upregulation of hyaluronan-binding protein TSG-6" doc
... K: Elevation of interleukin-8 (IL-8) levels in joint fluids of patients with rheumatoid arthritis and the induction by IL-8 of leuko- cyte infiltration and synovitis in rabbit joints. Lymphokine Cytokine ... separately with cell-permeable inhibitors of MAP kinase/ERK kinase-1/2 (PD98059), p38 (SB203580), protein kinase C (calphostin C), and tyrosine kinase (genistein),...
Ngày tải lên: 09/08/2014, 01:22
Báo cáo y học: "The induction of CCN2 by TGFβ1 involves Ets-1" ppsx
... addition of Ets-1 potentiates the TGFβ1 induction of CCN2 promoter activity (*p < 0.05), Fli-1 limits the TGFβ induction of CCN2 promoter activity relative to the induction of CCN2 promoter ... observed for CCN2, TGFβ induction of tenascin-C is potentiated by Ets- 1; however, the TGFβ -induction of type I collagen is impaired by Ets-1 [30,34,42]. Given t...
Ngày tải lên: 09/08/2014, 07:20
Báo cáo y học: "The matrix-forming phenotype of cultured human meniscus cells is enhanced after culture with fibroblast growth factor 2 and is further stimulated by hypoxia" pdf
... phenotype of cultured human meniscus cells is enhanced after culture with fibroblast growth factor 2 and is further stimulated by hypoxia Adetola B Adesida, Lisa M Grady, Wasim S Khan and Timothy ... times of P1 and P2 human meniscus cells were obtained by plating P1 and P2 meniscus cells at 5 ì 10 5 cells in 75 cm 2 tissue cul...
Ngày tải lên: 09/08/2014, 07:20
Báo cáo y học: "The spliceosomal autoantigen heterogeneous nuclear ribonucleoprotein A2 (hnRNP-A2) is a major T cell autoantigen in patients with systemic lupus erythematosus" potx
... hnRNP -A2 in patients with RA [27]. We observed that approximately half of the RA patients harbor T cells against hnRNP -A2 . In accordance with the perception of RA as an inflammatory, Th1 type systemic ... hnRNP -A2 may constitute an important T cell autoantigen in patients with SLE, indicating a potential role for it in the pathogenesis of this disorder...
Ngày tải lên: 09/08/2014, 08:22
Báo cáo y học: "The interferon induced with helicase domain 1 A946T polymorphism is not associated with rheumatoid arthritis" pptx
... [17 ]. We did not detect Table 1 Genotype frequencies of the interferon induced with helicase domain 1 A946T polymorphism Genotype frequency GG AG AA Rheumatoid arthritis Patients 12 6 (13 .7%) 446 ... role of the interferon induced with helicase domain 1 (IFIH1) A946T (rs1990760 A>G) variant in rheumatoid arthritis (RA), as this was recently associa...
Ngày tải lên: 09/08/2014, 10:20
Báo cáo y học: "The Ras guanine nucleotide exchange factor RasGRF1 promotes matrix metalloproteinase-3 production in rheumatoid arthritis synovial tissue" doc
... article The Ras guanine nucleotide exchange factor RasGRF1 promotes matrix metalloproteinase-3 production in rheumatoid arthritis synovial tissue Joana RF Abreu*, Daphne de Launay*, Marjolein E Sanders, ... 100. Figure 3 RasGRF1 is expressed as a truncated protein in synovial tissueRasGRF1 is expressed as a truncated protein in synovial tissue. Immu- nobl...
Ngày tải lên: 09/08/2014, 14:22
Báo cáo y học: "The role of a pseudocapsula in thymic epithelial tumors: outcome and correlation with established prognostic parameters. Results of a 20-year single centre retrospective analysis" pptx
... year experience in clinical treatment of thymomas as a result of a retrospective single centre analysis done within a Euro- pean university setting. The role of a pseudocapsula and its clinical significance ... metasta- sis in the liver. Recurrence was only seen in one case each in patients with an incomplete encapsulated thymoma or a missing capsula. Neo...
Ngày tải lên: 10/08/2014, 10:20
Báo cáo y học: " The MATISSE study: a randomised trial of group art therapy for people with schizophrenia" pdf
... criteria Exclusion criteria Aged 18 years or over Already receiving Art Therapy or another arts therapy (Music Therapy, Drama Therapy, or Dance/Movement Therapy) Clinical diagnosis of schizophrenia ... them [8]. The key ingredients of Art Therapy are considered to be the p rocess of making art, and the relationship that develops between the therapist and the par...
Ngày tải lên: 11/08/2014, 16:22
Báo cáo y học: "The anti-cyclic citrullinated peptide response in tuberculosis patients is not citrulline-dependent and sensitive to treatment" ppsx
... with citrullinated and corresponding arginine-containing peptides Figure 1 Reactivity of TB and healthy control sera with citrullinated and corresponding arginine-containing peptides. a) ELISA ... original work is properly cited. Research article The anti-cyclic citrullinated peptide response in tuberculosis patients is not citrulline-dependent and sensitive...
Ngày tải lên: 12/08/2014, 11:22
Báo cáo y học: "Selected amino acid mutations in HIV-1 B subtype gp41 are Associated with Specific gp120V3 signatures in the regulation of CoReceptor usag" pot
... extracellular domain of gp41 is consistent with the idea that gp41 may act as a scaffold in < /b> order to maintain the stability of the gp120 /gp41 complex, and therefore finally influencing the viral tropism ... likely that the principal driving force in < /b> the evolution of the V3 region of HIV-1 < /b> is the cell receptor usage, the escape from host i...
Ngày tải lên: 13/08/2014, 01:20
Báo cáo y học: "The interferon-inducible p47 (IRG) GTPases in vertebrates: loss of the cell autonomous resistance mechanism in the human lineage" docx
... in Extended phylogeny of the G domains of IRG and related proteinsFigure 5 Extended phylogeny of the G domains of IRG and related proteins. The phylogeny relates all of the IRG sequences described in this ... autoimmunity and allergy, arising from the adaptive immune system and many others arising from innate immu- nity [42-46]. Indeed, the interferon-inducible dy...
Ngày tải lên: 14/08/2014, 15:20