Báo cáo y học: "Vaccination response to tetanus toxoid and 23-valent pneumococcal vaccines following administration of a single dose of abatacept: a randomized, open-label, parallel group study in healthy subjects" pot

... for citation purposes) Vol 9 No 2 Research article Vaccination response to tetanus toxoid and 23-valent pneumococcal vaccines following administration of a single dose of abatacept: a randomized, ... tet- anus toxoid and 23-valent pneumococcal vaccines. Serum samples were obtained for subjects of Groups A and B at study days 14 and 28, f...

Ngày tải lên: 09/08/2014, 10:20

... Natl Acad Sci USA 1994, 91:8562-8566. 12. Morita Y, Yamamura M, Kawashima M, Harada S, Tsuji K, Shibuya K, Maruyama K, Makino H: Flow cytometric single- cell analysis of cytokine production by ... Ezawa K, Yamamura M, Matsui H, Ota Z, Makino H: Comparative analysis of CD45RA- and CD45RO-positive CD4+T cells in peripheral blood, synovial fluid, and synovial tissue in patients wit...

Ngày tải lên: 09/08/2014, 01:23

... methods Healthy premenopausal and postmenopausal women Fifty healthy premenopausal women (age 30 to 40 years, mean age 35 years) and 50 healthy untreated postmenopau- sal women (age 48 to 73 years, ... examples of immunostainigs of CTX-II and PIIANP and in situ hybridisations of type IIA collagen mRNAIllustrative examples of immunostainigs of CTX-II and PIIANP...

Ngày tải lên: 09/08/2014, 01:22

... pathophysiologic actions of NO in human chondro- cytes may be mediated via p38 MAPK activation has not been evaluated, and thus remains a potential point of therapy by inhibitors of p38 MAPK in cytokine-activated human ... p38 mitogen-activated protein kinase (MAPK) diminish inflammatory arthritis in experimental animals. This may be effected by diminishing the production of...

Ngày tải lên: 09/08/2014, 01:23

... for daily practice, since discontinuation of therapy at certain intervals, such as after 1 or 2 years of therapy, may become a standard approach. Payers and patients may want to make sure that further ... reimbursements and fees from the Centocor Amgen, and Wyeth and Abbott. Authors’ contributions XB: Preparation of data analysis, preparation of the manu- script, study c...

Ngày tải lên: 09/08/2014, 06:22

... 142:5371-5378. 38. Mano H, Yuasa T, Kameda T, Miyazawa K, Nakamaru Y, Shiokawa M, Mori Y, Yamada T, Miyata K, Shindo H, Azuma H, Hakeda Y, Kumegawa M: Mammalian mature osteoclasts as estrogen tar- get cells. ... methods Healthy premenopausal and postmenopausal women Fifty healthy premenopausal women (age 30 to 40 years, mean age 35 years) and 50 healthy untreated postmenopau-...

Ngày tải lên: 09/08/2014, 13:22

... EUSTAR and DNSS for the assessment of patients. In general, 26 clinical and laboratory findings were assessed and analyzed as described [12-14]. Briefly, for the evaluation of fibrotic skin changes ... Molecular characterization of an autoantigen of PM-Scl in the polymyositis/scleroderma overlap syndrome: a unique and complete human cDNA encoding an apparent 75-kD acidic...

Ngày tải lên: 09/08/2014, 01:22

... this study are listed as follows: anti-b-actin, anti-actin regulatory protein (CAPG) and anti-cathepsin D (CATD) antibodies (Santa Cruz Biotechnology, Santa Cruz, CA); anti-GFAP and anti-GAPDH antibodies ... were injected post surgery. Animal care was provided in accordance with the Laboratory Animal Welfare Act and Guide for the Care a nd Use of Laboratory Animals approved by I...

Ngày tải lên: 10/08/2014, 05:21

... cells Downstream signal transduction pathways were analyzed by studying the activation level of JAK/STAT and MAP kinase signaling components known to be mainly tyrosine phosphorylated in response to IL-6 ... CNTF (even at high concentrations) alone were able to activate the MAPK pathway. MAP kinases and STAT3 are rapidly activated within 10 min in response to Hyper-CNTF,...

Ngày tải lên: 22/02/2014, 07:20

... cause of disability that affects diarthrodial joints, being characterized by cartilage degradation, accompa- nied by local inflammation and changes in the subchondral bone. Increasing age, excessive ... [19], and to alter the regulation of tran- scription factors such as activator protein-1 [20] and NF-κB [21] that are involved in cartilage degradation and joint inflam- mati...

Ngày tải lên: 09/08/2014, 14:21