Báo cáo y học: " Replication of the genetic effects of IFN regulatory factor 5 (IRF5) on systemic lupus erythematosus in a Korean population" doc

... substantial contributions to study design, acquisition of data, drafting the manuscript, and analysis and interpretation of data. YK Sung and CB Choi have been involved in drafting the manuscript ... that IFN regulatory factor 5 (IRF5) gene polymorphisms are significantly associated with systemic lupus erythematosus (SLE) in several white populations. To replicat...

Ngày tải lên: 09/08/2014, 10:20

... out the x-ray evaluation using the SvdH method. VLA, MA, and MAA- T participated in the statistical analysis and helped to draft the manuscript. HC participated in the clinical data collection and helped ... the manufacturer's instructions. A 300-ng aliquot of DNA template and the inter- nal overlap primers F2: 5& apos;-TGTGACCACAGCAATGGG- TAGG-3', F3: 5& apo...

Ngày tải lên: 09/08/2014, 10:20

... syndrome). The proportion of genetic origin is estimated about 25 % of total congenital abnormalities. Mainly two conditions may contribute to a higher total prevalence of congenital abnormalities ... completeness of ascertainment, the diagnostic skill of experts, demographic and genetic characteristics of the study population, etc. In Hungary the total pre...

Ngày tải lên: 02/11/2012, 11:12

... fertilisation (IVF) or artificial insemination (AI), ‘washed’ sperm cells are simply incubated in a DNA-containing solution. As a potential tool for genetically manipulating animals, sperm-mediated ... MACs can be used, via pronuclear microinjection, to create transgenic animals in which the MACs are maintained autonomously [81]. In the context of human germline gene therapy...

Ngày tải lên: 03/11/2012, 10:01

... extension, in the case of E. coli agmatinase, of the loop indicated by the letter a. Fig. 5. Scheme of the binuclear manganese cluster and the localization of the side-chains of Asp 153 and Asn 153 in ... investigation in our laboratory. In any case, despite the structural differences between agmatinase and arginase, agmatine and arginine were fixed in esse...

Ngày tải lên: 21/02/2014, 01:21

... dis- ease. At entry to the study, 78% had active disease, and the median Ritchie Articular Index was 5 (range 0– 25) . The median age at onset was 45 years (range 15 77), and the median duration of ... [36]. These observations, including the C5 activation analyses, provide persuasive evidence that cartilage-bound anti-CII can participate in the initiation or perpetuation o...

Ngày tải lên: 09/08/2014, 01:23

... City, CA, USA), and association was examined in 308 SLE patients and 306 healthy individuals. Statistical analysis Association of each SNP was analyzed by chi-square test. Because of the replicative ... Shimane K, Nakamura Y, Toyama Y, Mochizuki T, Tsukahara S, Kawaguchi Y, Terai C, Hara M, Tomatsu T, Yamanaka H, Horiuchi T, Tao K, Yas- utomo K, Hamada D, Yasui N, Inoue H, Itakura...

Ngày tải lên: 09/08/2014, 13:22

... and acetyl-CoA synthetase (6.2.1.1) as well as enzymes involved in the conversion of acetyl-CoA to L-valine and the conversion of serine to cysteine. Annotation of metabolic enzymes and flux balance metabolic ... denotes the standard activity without IQ-143. A value of 0 .5 indicates that the activity of this enzyme was halved after administration of IQ-143, a value...

Ngày tải lên: 09/08/2014, 22:24

... article as: Moreno et al.: Longitudinal evaluation the pulmonary function of the pre and postoperative periods in the coronary artery bypass graft surgery of patients treated with a physiotherapy protocol. ... channel antagonists 4 1 CABG = coronary artery bypass graft; CAD = coronary artery disease; BMI = body mass index; AC = aortic clamping; ACE = angiotensin-converting enzym...

Ngày tải lên: 10/08/2014, 09:21

... Peptides analysed in this study. Protein Peptide Sequence Cardin motifs AKK24 AKKARAAKKARAAKKARAAKKARA ARK24 ARKKAAKAARKKAAKAARKKAAKA AHH24:1 AHHAHAAHHAHAAHHAHAAHHAHA AHH24:2 AHHHAAHAAHHHAAHAAHHHAAHA HMW kininogen KHN20 ... peptidoglycans, leading to the induction of an a- helical conformation, which in turn facilitates membrane interactions, membrane destabilization and finally, bact...

Ngày tải lên: 23/03/2014, 11:20